SG11202106392RA - Combination of dextromethorphan and bupropion for treating depression - Google Patents

Combination of dextromethorphan and bupropion for treating depression

Info

Publication number
SG11202106392RA
SG11202106392RA SG11202106392RA SG11202106392RA SG11202106392RA SG 11202106392R A SG11202106392R A SG 11202106392RA SG 11202106392R A SG11202106392R A SG 11202106392RA SG 11202106392R A SG11202106392R A SG 11202106392RA SG 11202106392R A SG11202106392R A SG 11202106392RA
Authority
SG
Singapore
Prior art keywords
dextromethorphan
bupropion
combination
treating depression
depression
Prior art date
Application number
SG11202106392RA
Inventor
Herriot Tabuteau
Original Assignee
Antecip Bioventures Ii Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antecip Bioventures Ii Llc filed Critical Antecip Bioventures Ii Llc
Publication of SG11202106392RA publication Critical patent/SG11202106392RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11202106392RA 2019-01-07 2020-01-07 Combination of dextromethorphan and bupropion for treating depression SG11202106392RA (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962789451P 2019-01-07 2019-01-07
US201962789431P 2019-01-07 2019-01-07
US201962789446P 2019-01-07 2019-01-07
US201962789488P 2019-01-07 2019-01-07
PCT/US2020/012612 WO2020146412A1 (en) 2019-01-07 2020-01-07 Combination of dextromethorphan and bupropion for treating depression

Publications (1)

Publication Number Publication Date
SG11202106392RA true SG11202106392RA (en) 2021-07-29

Family

ID=71521902

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202106392RA SG11202106392RA (en) 2019-01-07 2020-01-07 Combination of dextromethorphan and bupropion for treating depression

Country Status (16)

Country Link
EP (1) EP3908270A4 (en)
JP (1) JP2022516361A (en)
KR (1) KR20210110654A (en)
CN (4) CN114712356A (en)
AU (2) AU2020207261B2 (en)
BR (1) BR112020025902A2 (en)
CA (2) CA3223187A1 (en)
CL (1) CL2021001810A1 (en)
CO (1) CO2021008988A2 (en)
CR (1) CR20210368A (en)
EC (1) ECSP21051833A (en)
IL (1) IL284663A (en)
MX (1) MX2021008247A (en)
PE (1) PE20212249A1 (en)
SG (1) SG11202106392RA (en)
WO (1) WO2020146412A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11433067B2 (en) 2013-11-05 2022-09-06 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11969421B2 (en) 2013-11-05 2024-04-30 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
JP2022516361A (en) * 2019-01-07 2022-02-25 アンテシップ バイオベンチャーズ トゥー エルエルシー A combination of dextromethorphan and bupropion for the treatment of depression
EP4255433A4 (en) 2020-12-01 2024-05-29 Antecip Bioventures II LLC Bupropion and dextromethrophan for reduction of suicide risk in depression patients
CN117693336A (en) * 2021-07-21 2024-03-12 安泰赛普生物风投二代有限责任公司 Treatment of depression
WO2023225511A1 (en) * 2022-05-17 2023-11-23 Antecip Bioventures Ii Llc Treatment of depression
WO2024006853A1 (en) 2022-06-30 2024-01-04 Antecip Bioventures Ii Llc Treatment of poor metabolizers of dextromethorphan with a combination of bupropion and dextromethorphan
US11717518B1 (en) * 2022-06-30 2023-08-08 Antecip Bioventures Ii Llc Bupropion dosage forms with reduced food and alcohol dosing effects
US11844797B1 (en) 2023-04-20 2023-12-19 Antecip Bioventures Ii Llc Combination of dextromethorphan and bupropion for treating depression
US11730706B1 (en) 2022-07-07 2023-08-22 Antecip Bioventures Ii Llc Treatment of depression in certain patient populations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009525343A (en) * 2006-02-03 2009-07-09 アバニール・ファーマシューティカルズ Pharmaceutical composition comprising dextromethorphan and quinidine for the treatment of depression, anxiety and neurodegenerative diseases
JP2015533155A (en) * 2012-10-11 2015-11-19 アイエックス バイオファーマ リミテッド Solid dosage form
EP2950799B1 (en) * 2013-01-30 2019-12-04 Pharmorx Therapeutics, Inc. Treatments for depression and other diseases with a low dose agent
US10512643B2 (en) * 2013-11-05 2019-12-24 Antecip Bioventures Ii Llc Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic effects
NZ758432A (en) * 2013-11-05 2021-07-30 Antecip Bioventures Ii Llc Compositions and methods comprising bupropion or related compounds and dextromethorphan
US9402843B2 (en) * 2013-11-05 2016-08-02 Antecip Bioventures Ii Llc Compositions and methods of using threohydroxybupropion for therapeutic purposes
RU2020116666A (en) * 2014-09-14 2020-07-31 Аванир Фармасьютикалз, Инк. PHARMACEUTICAL COMPOSITIONS CONTAINING A DEXTROMETORPHANE COMPOUND AND QUINIDINE FOR THE TREATMENT OF EXCITATION IN DEMENSE
KR102524253B1 (en) * 2014-11-21 2023-04-20 안테씨프 바이오벤쳐스 투 엘엘씨 Methods of modulating drug plasma levels using erythrohydroxybupropion
JP2022516361A (en) * 2019-01-07 2022-02-25 アンテシップ バイオベンチャーズ トゥー エルエルシー A combination of dextromethorphan and bupropion for the treatment of depression

Also Published As

Publication number Publication date
BR112020025902A2 (en) 2021-07-13
PE20212249A1 (en) 2021-11-24
CN114712356A (en) 2022-07-08
EP3908270A4 (en) 2022-02-16
CL2021001810A1 (en) 2022-03-04
CA3223187A1 (en) 2020-07-16
AU2020207261B2 (en) 2023-04-13
JP2022516361A (en) 2022-02-25
ECSP21051833A (en) 2021-11-18
AU2023204348A1 (en) 2023-07-27
CA3126062C (en) 2024-02-06
WO2020146412A1 (en) 2020-07-16
IL284663A (en) 2021-08-31
AU2020207261A1 (en) 2021-07-08
CN112437659B (en) 2022-04-12
CO2021008988A2 (en) 2021-09-09
KR20210110654A (en) 2021-09-08
EP3908270A1 (en) 2021-11-17
CR20210368A (en) 2021-12-10
CN114712357A (en) 2022-07-08
CA3126062A1 (en) 2020-07-16
CN112437659A (en) 2021-03-02
CN114712358A (en) 2022-07-08
MX2021008247A (en) 2021-08-16

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