SG11202105645PA - Ancestry-specific genetic risk scores - Google Patents
Ancestry-specific genetic risk scoresInfo
- Publication number
- SG11202105645PA SG11202105645PA SG11202105645PA SG11202105645PA SG11202105645PA SG 11202105645P A SG11202105645P A SG 11202105645PA SG 11202105645P A SG11202105645P A SG 11202105645PA SG 11202105645P A SG11202105645P A SG 11202105645PA SG 11202105645P A SG11202105645P A SG 11202105645PA
- Authority
- SG
- Singapore
- Prior art keywords
- ancestry
- risk scores
- specific genetic
- genetic risk
- scores
- Prior art date
Links
Classifications
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B10/00—ICT specially adapted for evolutionary bioinformatics, e.g. phylogenetic tree construction or analysis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
- G06F17/10—Complex mathematical operations
- G06F17/15—Correlation function computation including computation of convolution operations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/40—Population genetics; Linkage disequilibrium
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/30—Unsupervised data analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H15/00—ICT specially adapted for medical reports, e.g. generation or transmission thereof
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/30—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H70/00—ICT specially adapted for the handling or processing of medical references
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Theoretical Computer Science (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Data Mining & Analysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Databases & Information Systems (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Primary Health Care (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Physiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Bioethics (AREA)
- Microbiology (AREA)
- Software Systems (AREA)
- Mathematical Analysis (AREA)
- Mathematical Optimization (AREA)
- Pure & Applied Mathematics (AREA)
- Computational Mathematics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862772565P | 2018-11-28 | 2018-11-28 | |
| US16/216,940 US10468141B1 (en) | 2018-11-28 | 2018-12-11 | Ancestry-specific genetic risk scores |
| PCT/IB2019/001179 WO2020109858A1 (en) | 2018-11-28 | 2019-10-31 | Ancestry-specific genetic risk scores |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202105645PA true SG11202105645PA (en) | 2021-06-29 |
Family
ID=68391819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202105645PA SG11202105645PA (en) | 2018-11-28 | 2019-10-31 | Ancestry-specific genetic risk scores |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10468141B1 (en) |
| EP (1) | EP3888092A1 (en) |
| JP (1) | JP2022511765A (en) |
| KR (1) | KR20210100650A (en) |
| CN (1) | CN113614833B (en) |
| AU (1) | AU2019387560A1 (en) |
| BR (1) | BR112021010323A2 (en) |
| CA (1) | CA3121118A1 (en) |
| GB (1) | GB2595373A (en) |
| MX (1) | MX2021006266A (en) |
| SG (1) | SG11202105645PA (en) |
| TW (1) | TWI816927B (en) |
| WO (1) | WO2020109858A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7844609B2 (en) | 2007-03-16 | 2010-11-30 | Expanse Networks, Inc. | Attribute combination discovery |
| EP3276526A1 (en) | 2008-12-31 | 2018-01-31 | 23Andme, Inc. | Finding relatives in a database |
| US10777302B2 (en) * | 2012-06-04 | 2020-09-15 | 23Andme, Inc. | Identifying variants of interest by imputation |
| CN111394441B (en) * | 2020-04-30 | 2022-11-15 | 北京和合医学诊断技术股份有限公司 | Primer group, kit and method for amplification of vitamin A related genes |
| US20230207053A1 (en) * | 2020-05-15 | 2023-06-29 | The Scripps Research Institute | Adjusted Polygenic Risk Score Calculation Algorithm and Process |
| US20220101945A1 (en) * | 2020-09-28 | 2022-03-31 | Ut-Battelle, Llc | Specific structural variants discovered with non-mendelian inheritance |
| CN113201593B (en) * | 2021-05-25 | 2024-01-23 | 广州盛世中豪运动科技有限公司 | Primer probe combination product for detecting ACTN3 genotype |
| CN113337597B (en) * | 2021-07-02 | 2022-10-04 | 厦门市妇幼保健院（厦门市计划生育服务中心） | Detection kit for pregnancy vitamin A deficiency risk assessment and application method |
| TWI795139B (en) * | 2021-12-23 | 2023-03-01 | 國立陽明交通大學 | Automated pathogenic mutation classifier and classification method thereof |
| CN115206420B (en) * | 2022-06-27 | 2023-05-23 | 南方医科大学南方医院 | Construction method and application of schizophrenia abnormal gene-metabolism regulation network |
| CN117711488B (en) * | 2023-11-29 | 2024-07-02 | 东莞博奥木华基因科技有限公司 | Gene haplotype detection method based on long-reading long-sequencing and application thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2362533A1 (en) * | 1999-02-22 | 2000-08-31 | Variagenics, Inc. | Gene sequence variations with utility in determining the treatment of disease |
| FI116468B (en) * | 2002-04-04 | 2005-11-30 | Licentia Oy | Gene mapping method from genotype and phenotype data and computer readable memory means and computer systems to perform the method |
| US7645575B2 (en) * | 2004-09-08 | 2010-01-12 | Xdx, Inc. | Genes useful for diagnosing and monitoring inflammation related disorders |
| EP2437191B1 (en) * | 2005-11-26 | 2017-04-26 | Natera, Inc. | Method and system for detecting chromosomal abnormalities |
| BRPI0807927A2 (en) | 2007-02-21 | 2014-06-24 | Decode Genetics Ehf | METHODS FOR DETERMINING CARDIOVASCULAR DISEASE SUSTAINABILITY IN A HUMAN INDIVIDUAL, IDENTIFICATION OF A BOOKMARK FOR USE TO ASSESS CARDIOVASCULAR DISEASE, FOR GENOTIPAYING A SAMPLE OF A PREPARATILE FOR NUCLEAR PROBABLE ACTIVITY PROGNOSIS OF A DIAGNOSTIC INDIVIDUAL WITH CARDIOVASCULAR DISEASE, AND TO MONITOR PROGRESS OF TREATMENT OF AN INDIVIDUAL GOING TO TREATMENT FOR CARDIOVASCULAR DISEASE, A HUMAN DEVELOPMENT, CARDIOVASCULAR DISEASE , DEVICE FOR DETERMINING A GENETIC INDICATOR FOR CARDIOVASCULAR DISEASE IN A HUMAN GUY |
| EP2215253B1 (en) * | 2007-09-26 | 2016-04-27 | Navigenics, Inc. | Method and computer system for correlating genotype to phenotype using population data |
| US20100036720A1 (en) * | 2008-04-11 | 2010-02-11 | Microsoft Corporation | Ubiquitous intent-based customer incentive scheme |
| US9218451B2 (en) | 2008-08-26 | 2015-12-22 | 23Andme, Inc. | Processing data from genotyping chips |
| US8428886B2 (en) | 2008-08-26 | 2013-04-23 | 23Andme, Inc. | Genotype calling |
| US8594700B2 (en) * | 2010-02-04 | 2013-11-26 | Jan Nabbefeld | Location-determining system and method |
| EP2773954B1 (en) * | 2011-10-31 | 2018-04-11 | The Scripps Research Institute | Systems and methods for genomic annotation and distributed variant interpretation |
| US9213944B1 (en) | 2012-11-08 | 2015-12-15 | 23Andme, Inc. | Trio-based phasing using a dynamic Bayesian network |
| US9213947B1 (en) | 2012-11-08 | 2015-12-15 | 23Andme, Inc. | Scalable pipeline for local ancestry inference |
| US9910962B1 (en) | 2013-01-22 | 2018-03-06 | Basehealth, Inc. | Genetic and environmental risk engine and methods thereof |
| KR20180086264A (en) * | 2015-12-23 | 2018-07-30 | 테크놀로지안 투트키무스케스쿠스 브이티티 오와이 | How to get an indicator signal from a cell |
| ES2967443T3 (en) * | 2016-07-06 | 2024-04-30 | Guardant Health Inc | Cell-Free Nucleic Acid Fragmentome Profiling Procedures |
-
2018
- 2018-12-11 US US16/216,940 patent/US10468141B1/en active Active
-
2019
- 2019-10-31 SG SG11202105645PA patent/SG11202105645PA/en unknown
- 2019-10-31 GB GB2109153.3A patent/GB2595373A/en not_active Withdrawn
- 2019-10-31 EP EP19836510.8A patent/EP3888092A1/en active Pending
- 2019-10-31 TW TW108139510A patent/TWI816927B/en active
- 2019-10-31 BR BR112021010323-6A patent/BR112021010323A2/en unknown
- 2019-10-31 KR KR1020217019839A patent/KR20210100650A/en unknown
- 2019-10-31 JP JP2021529690A patent/JP2022511765A/en active Pending
- 2019-10-31 MX MX2021006266A patent/MX2021006266A/en unknown
- 2019-10-31 CN CN201980090481.0A patent/CN113614833B/en active Active
- 2019-10-31 CA CA3121118A patent/CA3121118A1/en active Pending
- 2019-10-31 WO PCT/IB2019/001179 patent/WO2020109858A1/en unknown
- 2019-10-31 AU AU2019387560A patent/AU2019387560A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20210100650A (en) | 2021-08-17 |
| TWI816927B (en) | 2023-10-01 |
| GB202109153D0 (en) | 2021-08-11 |
| BR112021010323A2 (en) | 2021-08-24 |
| MX2021006266A (en) | 2021-09-10 |
| CA3121118A1 (en) | 2020-06-04 |
| EP3888092A1 (en) | 2021-10-06 |
| CN113614833B (en) | 2024-04-23 |
| CN113614833A (en) | 2021-11-05 |
| WO2020109858A1 (en) | 2020-06-04 |
| GB2595373A (en) | 2021-11-24 |
| US10468141B1 (en) | 2019-11-05 |
| AU2019387560A1 (en) | 2021-07-15 |
| TW202036583A (en) | 2020-10-01 |
| JP2022511765A (en) | 2022-02-01 |
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