SG11202104743WA - Modified closed-ended dna (cedna) comprising symmetrical modified inverted terminal repeats - Google Patents
Modified closed-ended dna (cedna) comprising symmetrical modified inverted terminal repeatsInfo
- Publication number
- SG11202104743WA SG11202104743WA SG11202104743WA SG11202104743WA SG11202104743WA SG 11202104743W A SG11202104743W A SG 11202104743WA SG 11202104743W A SG11202104743W A SG 11202104743WA SG 11202104743W A SG11202104743W A SG 11202104743WA SG 11202104743W A SG11202104743W A SG 11202104743WA
- Authority
- SG
- Singapore
- Prior art keywords
- modified
- cedna
- inverted terminal
- terminal repeats
- symmetrical
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0091—Purification or manufacturing processes for gene therapy compositions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/106—Plasmid DNA for vertebrates
- C12N2800/107—Plasmid DNA for vertebrates for mammalian
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862757872P | 2018-11-09 | 2018-11-09 | |
US201862757892P | 2018-11-09 | 2018-11-09 | |
PCT/US2019/060395 WO2020097417A1 (en) | 2018-11-09 | 2019-11-08 | Modified closed-ended dna (cedna) comprising symmetrical modified inverted terminal repeats |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202104743WA true SG11202104743WA (en) | 2021-06-29 |
Family
ID=70612486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202104743WA SG11202104743WA (en) | 2018-11-09 | 2019-11-08 | Modified closed-ended dna (cedna) comprising symmetrical modified inverted terminal repeats |
Country Status (13)
Country | Link |
---|---|
US (1) | US20210388379A1 (en) |
EP (1) | EP3877528A4 (en) |
JP (1) | JP2022506771A (en) |
KR (1) | KR20210090619A (en) |
CN (1) | CN113316640A (en) |
AU (1) | AU2019376663A1 (en) |
BR (1) | BR112021007102A2 (en) |
CA (1) | CA3119310A1 (en) |
IL (1) | IL282925A (en) |
MA (1) | MA54188A (en) |
MX (1) | MX2021004842A (en) |
SG (1) | SG11202104743WA (en) |
WO (1) | WO2020097417A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3999646A4 (en) * | 2019-07-17 | 2023-08-30 | Generation Bio Co. | Compositions and production of nicked closed-ended dna vectors |
WO2021011842A1 (en) * | 2019-07-17 | 2021-01-21 | Generation Bio Co. | Synthetic production of single-stranded adeno associated viral dna vectors |
AU2021314809A1 (en) | 2020-07-27 | 2023-02-23 | Anjarium Biosciences Ag | Compositions of DNA molecules, methods of making therefor, and methods of use thereof |
CN117802161A (en) * | 2022-06-30 | 2024-04-02 | 苏州吉恒基因科技有限公司 | Accurate recombinant adeno-associated virus vector and application thereof |
CN116110602B (en) * | 2023-04-13 | 2023-06-20 | 云南医无界医疗网络科技有限公司 | Information processing method and system applied to medical community |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2500434A1 (en) * | 2011-03-12 | 2012-09-19 | Association Institut de Myologie | Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery |
MX2018000307A (en) * | 2015-06-23 | 2018-05-02 | Childrens Hospital Philadelphia | Modified factor ix, and compositions, methods and uses for gene transfer to cells, organs and tissues. |
CN109195636B (en) * | 2016-03-03 | 2022-07-05 | 马萨诸塞大学 | End-blocked linear duplex DNA for non-viral gene transfer |
JP2021511047A (en) * | 2018-01-19 | 2021-05-06 | ジェネレーション バイオ カンパニー | Process for obtaining closed-ended DNA vectors and ceDNA vectors that can be obtained from cell-free synthesis |
MX2020008676A (en) * | 2018-02-22 | 2020-09-25 | Generation Bio Co | Controlled expression of transgenes using close-ended dna (cedna) vectors. |
-
2019
- 2019-11-08 CA CA3119310A patent/CA3119310A1/en active Pending
- 2019-11-08 WO PCT/US2019/060395 patent/WO2020097417A1/en active Application Filing
- 2019-11-08 AU AU2019376663A patent/AU2019376663A1/en active Pending
- 2019-11-08 BR BR112021007102-4A patent/BR112021007102A2/en unknown
- 2019-11-08 EP EP19881504.5A patent/EP3877528A4/en active Pending
- 2019-11-08 US US17/290,787 patent/US20210388379A1/en active Pending
- 2019-11-08 KR KR1020217012806A patent/KR20210090619A/en active Search and Examination
- 2019-11-08 SG SG11202104743WA patent/SG11202104743WA/en unknown
- 2019-11-08 CN CN201980073843.5A patent/CN113316640A/en active Pending
- 2019-11-08 JP JP2021524359A patent/JP2022506771A/en active Pending
- 2019-11-08 MA MA054188A patent/MA54188A/en unknown
- 2019-11-08 MX MX2021004842A patent/MX2021004842A/en unknown
-
2021
- 2021-05-04 IL IL282925A patent/IL282925A/en unknown
Also Published As
Publication number | Publication date |
---|---|
BR112021007102A2 (en) | 2021-08-03 |
WO2020097417A9 (en) | 2020-06-18 |
EP3877528A1 (en) | 2021-09-15 |
JP2022506771A (en) | 2022-01-17 |
AU2019376663A1 (en) | 2021-06-24 |
CA3119310A1 (en) | 2020-05-14 |
MX2021004842A (en) | 2021-06-08 |
MA54188A (en) | 2021-09-15 |
WO2020097417A1 (en) | 2020-05-14 |
KR20210090619A (en) | 2021-07-20 |
EP3877528A4 (en) | 2022-11-30 |
IL282925A (en) | 2021-06-30 |
US20210388379A1 (en) | 2021-12-16 |
CN113316640A (en) | 2021-08-27 |
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