SG11202104463YA - Anti-human fn14 antibody - Google Patents

Anti-human fn14 antibody

Info

Publication number
SG11202104463YA
SG11202104463YA SG11202104463YA SG11202104463YA SG11202104463YA SG 11202104463Y A SG11202104463Y A SG 11202104463YA SG 11202104463Y A SG11202104463Y A SG 11202104463YA SG 11202104463Y A SG11202104463Y A SG 11202104463YA SG 11202104463Y A SG11202104463Y A SG 11202104463YA
Authority
SG
Singapore
Prior art keywords
antibody
human
Prior art date
Application number
SG11202104463YA
Inventor
Misato Ito
Risa Kashiwagi
Masakatsu Kawakami
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of SG11202104463YA publication Critical patent/SG11202104463YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11202104463YA 2018-10-31 2019-10-30 Anti-human fn14 antibody SG11202104463YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018205995 2018-10-31
PCT/JP2019/042587 WO2020090892A1 (en) 2018-10-31 2019-10-30 Anti-human fn14 antibody

Publications (1)

Publication Number Publication Date
SG11202104463YA true SG11202104463YA (en) 2021-05-28

Family

ID=70464144

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104463YA SG11202104463YA (en) 2018-10-31 2019-10-30 Anti-human fn14 antibody

Country Status (17)

Country Link
US (1) US20210388096A1 (en)
EP (1) EP3875114A4 (en)
JP (1) JP7415939B2 (en)
KR (1) KR20210084473A (en)
CN (1) CN112930195B (en)
AR (1) AR123671A1 (en)
AU (1) AU2019369771A1 (en)
BR (1) BR112021008424A2 (en)
CA (1) CA3117930A1 (en)
CO (1) CO2021005768A2 (en)
IL (1) IL282650B1 (en)
JO (1) JOP20210093A1 (en)
MA (1) MA54097A (en)
MX (1) MX2021004976A (en)
SG (1) SG11202104463YA (en)
WO (1) WO2020090892A1 (en)
ZA (1) ZA202102879B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022153997A1 (en) * 2021-01-13 2022-07-21 アステラス製薬株式会社 MULTISPECIFIC ANTIBODY BONDING TO ActRIIA, ActRIIB, AND Fn14
WO2023062848A1 (en) * 2021-10-14 2023-04-20 Astellas Pharma Inc. Pharmaceutical composition comprising anti-human fnl4 antibody or antigen-binding fragment thereof for preventing or treating cancer

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
AU681633B2 (en) 1993-03-11 1997-09-04 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Anti-HIV monoclonal antibody
US6824773B2 (en) * 1999-12-20 2004-11-30 Immunex Corporation TWEAK receptor
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
CN102225200A (en) * 2005-03-07 2011-10-26 健泰科生物技术公司 Methods and compositions for modulating TWEAK and FN14 activity
PL1888113T3 (en) * 2005-05-27 2014-11-28 Biogen Ma Inc Tweak binding antibodies
CN102006886A (en) * 2007-08-03 2011-04-06 菲赛特生物技术公司 Therapeutic use of anti-tweak receptor antibodies
AU2009246640A1 (en) * 2008-05-15 2009-11-19 Biogen Idec Ma Inc. Anti-Fn14 antibodies and uses thereof
US8093006B2 (en) * 2009-04-02 2012-01-10 Hoffmann-La Roche Inc. Antibodies against human tweak and uses thereof
EP2683740B1 (en) * 2011-03-10 2018-07-04 Omeros Corporation Generation of anti-fn14 monoclonal antibodies by ex-vivo accelerated antibody evolution
ES2748021T3 (en) * 2011-08-23 2020-03-12 Univ La Trobe Fn14 binding proteins and uses thereof
JP2016000003A (en) * 2013-04-19 2016-01-07 アステラス製薬株式会社 Novel anti-human tweak antibodies
SG11201509116VA (en) * 2013-06-14 2015-12-30 Bayer Pharma AG Anti-tweakr antibodies and uses thereof
US9238034B2 (en) * 2013-07-09 2016-01-19 The Translational Genomics Research Institute FN14 antagonists and therapeutic uses thereof

Also Published As

Publication number Publication date
IL282650A (en) 2021-06-30
US20210388096A1 (en) 2021-12-16
TW202035459A (en) 2020-10-01
CN112930195B (en) 2024-03-19
JP7415939B2 (en) 2024-01-17
IL282650B1 (en) 2024-05-01
CN112930195A (en) 2021-06-08
EP3875114A4 (en) 2022-08-10
AU2019369771A1 (en) 2021-06-03
AR123671A1 (en) 2023-01-04
ZA202102879B (en) 2022-10-26
WO2020090892A1 (en) 2020-05-07
CA3117930A1 (en) 2020-05-07
EP3875114A1 (en) 2021-09-08
MX2021004976A (en) 2021-06-15
MA54097A (en) 2022-02-09
JPWO2020090892A1 (en) 2021-09-24
CO2021005768A2 (en) 2021-05-10
BR112021008424A2 (en) 2021-09-28
KR20210084473A (en) 2021-07-07
JOP20210093A1 (en) 2023-01-30

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