SG11202104463YA - Anti-human fn14 antibody - Google Patents

Anti-human fn14 antibody

Info

Publication number
SG11202104463YA
SG11202104463YA SG11202104463YA SG11202104463YA SG11202104463YA SG 11202104463Y A SG11202104463Y A SG 11202104463YA SG 11202104463Y A SG11202104463Y A SG 11202104463YA SG 11202104463Y A SG11202104463Y A SG 11202104463YA SG 11202104463Y A SG11202104463Y A SG 11202104463YA
Authority
SG
Singapore
Prior art keywords
antibody
human
Prior art date
Application number
SG11202104463YA
Inventor
Misato Ito
Risa Kashiwagi
Masakatsu Kawakami
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of SG11202104463YA publication Critical patent/SG11202104463YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11202104463YA 2018-10-31 2019-10-30 Anti-human fn14 antibody SG11202104463YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018205995 2018-10-31
PCT/JP2019/042587 WO2020090892A1 (en) 2018-10-31 2019-10-30 Anti-human fn14 antibody

Publications (1)

Publication Number Publication Date
SG11202104463YA true SG11202104463YA (en) 2021-05-28

Family

ID=70464144

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104463YA SG11202104463YA (en) 2018-10-31 2019-10-30 Anti-human fn14 antibody

Country Status (18)

Country Link
US (1) US20210388096A1 (en)
EP (1) EP3875114A4 (en)
JP (1) JP7415939B2 (en)
KR (1) KR20210084473A (en)
CN (1) CN112930195B (en)
AR (1) AR123671A1 (en)
AU (1) AU2019369771A1 (en)
BR (1) BR112021008424A2 (en)
CA (1) CA3117930A1 (en)
CO (1) CO2021005768A2 (en)
IL (1) IL282650B2 (en)
JO (1) JOP20210093A1 (en)
MA (1) MA54097A (en)
MX (1) MX2021004976A (en)
SG (1) SG11202104463YA (en)
TW (1) TWI843763B (en)
WO (1) WO2020090892A1 (en)
ZA (1) ZA202102879B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116802298A (en) 2021-01-13 2023-09-22 安斯泰来制药株式会社 Multispecific antibodies that bind to ActRIIA, actRIIB and Fn14
WO2023062848A1 (en) * 2021-10-14 2023-04-20 Astellas Pharma Inc. Pharmaceutical composition comprising anti-human fnl4 antibody or antigen-binding fragment thereof for preventing or treating cancer

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US6114143A (en) 1993-03-11 2000-09-05 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Anti-HIV monoclonal antibody
EP2298334A3 (en) 1999-12-20 2012-04-04 Immunex Corporation Tweak receptor
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
BRPI0608012A2 (en) * 2005-03-07 2009-11-03 Genentech Inc cancer treatment method, nk cell activity increase method, innate th1 response or activity increase method, method of treatment of a th2-mediated dysfunction, method of treatment of an immune disease, uses of an antagonist molecule and use of an agonist molecule
SI2460831T1 (en) * 2005-05-27 2017-01-31 Biogen Ma Inc. Tweak binding antibodies
KR20100053607A (en) 2007-08-03 2010-05-20 패시트 바이오테크 코포레이션 Therapeutic use of anti-tweak receptor antibodies
JP2011523414A (en) * 2008-05-15 2011-08-11 バイオジェン・アイデック・エムエイ・インコーポレイテッド Anti-FN14 antibodies and uses thereof
US8093006B2 (en) * 2009-04-02 2012-01-10 Hoffmann-La Roche Inc. Antibodies against human tweak and uses thereof
WO2012122513A2 (en) * 2011-03-10 2012-09-13 Omeros Corporation Generation of anti-fn14 monoclonal antibodies by ex-vivo accelerated antibody evolution
SG2014010334A (en) * 2011-08-23 2014-06-27 Transbio Ltd Fn14 binding proteins and uses thereof
JP2016000003A (en) * 2013-04-19 2016-01-07 アステラス製薬株式会社 Novel anti-human tweak antibodies
RU2016100892A (en) * 2013-06-14 2017-07-19 Байер Фарма Акциенгезельшафт ANTIBODIES AGAINST TWEAKR AND THEIR APPLICATION
EP3019874B1 (en) * 2013-07-09 2019-08-21 The Translational Genomics Research Institute Compositions and methods of screening for compounds that modulate activity at a tweak binding site on a crd of fn14

Also Published As

Publication number Publication date
EP3875114A4 (en) 2022-08-10
MA54097A (en) 2022-02-09
AR123671A1 (en) 2023-01-04
CA3117930A1 (en) 2020-05-07
JPWO2020090892A1 (en) 2021-09-24
IL282650A (en) 2021-06-30
CN112930195B (en) 2024-03-19
KR20210084473A (en) 2021-07-07
WO2020090892A1 (en) 2020-05-07
CO2021005768A2 (en) 2021-05-10
ZA202102879B (en) 2022-10-26
BR112021008424A2 (en) 2021-09-28
AU2019369771A1 (en) 2021-06-03
TWI843763B (en) 2024-06-01
JP7415939B2 (en) 2024-01-17
US20210388096A1 (en) 2021-12-16
JOP20210093A1 (en) 2023-01-30
IL282650B2 (en) 2024-09-01
IL282650B1 (en) 2024-05-01
EP3875114A1 (en) 2021-09-08
TW202035459A (en) 2020-10-01
MX2021004976A (en) 2021-06-15
CN112930195A (en) 2021-06-08

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