SG11202104161RA - Protein tyrosine-tyrosine analogs and methods of using the same - Google Patents

Protein tyrosine-tyrosine analogs and methods of using the same

Info

Publication number
SG11202104161RA
SG11202104161RA SG11202104161RA SG11202104161RA SG11202104161RA SG 11202104161R A SG11202104161R A SG 11202104161RA SG 11202104161R A SG11202104161R A SG 11202104161RA SG 11202104161R A SG11202104161R A SG 11202104161RA SG 11202104161R A SG11202104161R A SG 11202104161RA
Authority
SG
Singapore
Prior art keywords
tyrosine
methods
same
analogs
protein
Prior art date
Application number
SG11202104161RA
Inventor
Daniel Anthony Briere
Daniel Christopher Lopes
Avinash Muppidi
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SG11202104161RA publication Critical patent/SG11202104161RA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57545Neuropeptide Y
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542Carboxylic acids, e.g. a fatty acid or an amino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG11202104161RA 2018-11-01 2019-10-28 Protein tyrosine-tyrosine analogs and methods of using the same SG11202104161RA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862754244P 2018-11-01 2018-11-01
US201962793544P 2019-01-17 2019-01-17
PCT/US2019/058259 WO2020092191A1 (en) 2018-11-01 2019-10-28 Protein tyrosine-tyrosine analogs and methods of using the same

Publications (1)

Publication Number Publication Date
SG11202104161RA true SG11202104161RA (en) 2021-05-28

Family

ID=68582448

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104161RA SG11202104161RA (en) 2018-11-01 2019-10-28 Protein tyrosine-tyrosine analogs and methods of using the same

Country Status (20)

Country Link
US (2) US11155592B2 (en)
EP (1) EP3873924A1 (en)
JP (2) JP7280949B2 (en)
CN (1) CN112888705A (en)
AU (2) AU2019371232B2 (en)
BR (1) BR112021006782A2 (en)
CA (1) CA3118002A1 (en)
CL (1) CL2021001073A1 (en)
CO (1) CO2021005514A2 (en)
CR (1) CR20210192A (en)
DO (1) DOP2021000072A (en)
EC (1) ECSP21030933A (en)
IL (1) IL282177A (en)
MX (1) MX2021004930A (en)
MY (1) MY197530A (en)
PE (1) PE20211466A1 (en)
PH (1) PH12021550964A1 (en)
SG (1) SG11202104161RA (en)
TW (2) TWI749381B (en)
WO (1) WO2020092191A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI749381B (en) * 2018-11-01 2021-12-11 美商美國禮來大藥廠 Protein tyrosine-tyrosine analogs and methods of using the same
MX2022005661A (en) 2019-11-11 2022-09-07 Boehringer Ingelheim Int Npy2 receptor agonists.
CA3185637A1 (en) 2020-08-07 2022-02-10 Boehringer Ingelheim International Gmbh Soluble npy2 receptor agonists
WO2022159395A1 (en) 2021-01-20 2022-07-28 Viking Therapeutics, Inc. Compositions and methods for the treatment of metabolic and liver disorders
WO2024038067A1 (en) 2022-08-18 2024-02-22 Boehringer Ingelheim International Gmbh Combination therapy comprising long acting glp-1/glucagon and npy2 receptor agonists
WO2024050289A1 (en) 2022-08-29 2024-03-07 Eli Lilly And Company Compositions for oral delivery
CN117603364A (en) * 2022-09-30 2024-02-27 广西医科大学附属肿瘤医院 GLP-1/glucon/Y 2 Receptor triple agonists and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004515533A (en) 2000-12-14 2004-05-27 アミリン・ファーマシューティカルズ,インコーポレイテッド Peptide YY and peptide YY agonist for treating metabolic disorders
AU2003201998C1 (en) * 2002-01-10 2012-10-25 Imperial Innovations Limited Modification of feeding behavior
US20070027073A1 (en) 2003-04-08 2007-02-01 Menachem Rubinstein Long-acting derivatives of pyy agonists
CA2723855A1 (en) 2008-05-16 2009-11-19 Novo Nordisk A/S Long-acting y2 and/or y4 receptor agonists
WO2011033068A1 (en) * 2009-09-18 2011-03-24 Novo Nordisk A/S Long-acting y2 receptor agonists
WO2011058165A1 (en) * 2009-11-13 2011-05-19 Novo Nordisk A/S Long-acting y2 receptor agonists
TW201534616A (en) * 2013-05-02 2015-09-16 Glaxosmithkline Ip Dev Ltd Therapeutic peptides
MX369818B (en) * 2013-11-15 2019-11-22 Novo Nordisk As Selective pyy compounds and uses thereof.
AR104984A1 (en) 2015-06-12 2017-08-30 Novo Nordisk As SELECTIVE COMPOUNDS FOR PYY AND ITS USES
TWI749381B (en) * 2018-11-01 2021-12-11 美商美國禮來大藥廠 Protein tyrosine-tyrosine analogs and methods of using the same

Also Published As

Publication number Publication date
PH12021550964A1 (en) 2021-11-29
US20200140514A1 (en) 2020-05-07
US11820803B2 (en) 2023-11-21
AU2019371232B2 (en) 2022-07-14
US11155592B2 (en) 2021-10-26
JP7280949B2 (en) 2023-05-24
TW202208410A (en) 2022-03-01
MY197530A (en) 2023-06-21
TW202033544A (en) 2020-09-16
CN112888705A (en) 2021-06-01
KR20210071038A (en) 2021-06-15
CL2021001073A1 (en) 2021-11-12
IL282177A (en) 2021-05-31
US20220025009A1 (en) 2022-01-27
BR112021006782A2 (en) 2021-07-13
PE20211466A1 (en) 2021-08-05
AU2022231763A1 (en) 2022-10-06
AU2022231763B2 (en) 2024-05-09
CR20210192A (en) 2021-05-18
MX2021004930A (en) 2021-06-08
DOP2021000072A (en) 2021-05-31
CO2021005514A2 (en) 2021-05-10
JP2023082013A (en) 2023-06-13
WO2020092191A1 (en) 2020-05-07
EP3873924A1 (en) 2021-09-08
TWI749381B (en) 2021-12-11
CA3118002A1 (en) 2020-05-07
ECSP21030933A (en) 2021-05-31
AU2019371232A1 (en) 2021-05-20
JP2022506070A (en) 2022-01-17

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