SG11202104051VA - Miniaturized dystrophins and uses thereof - Google Patents
Miniaturized dystrophins and uses thereofInfo
- Publication number
- SG11202104051VA SG11202104051VA SG11202104051VA SG11202104051VA SG11202104051VA SG 11202104051V A SG11202104051V A SG 11202104051VA SG 11202104051V A SG11202104051V A SG 11202104051VA SG 11202104051V A SG11202104051V A SG 11202104051VA SG 11202104051V A SG11202104051V A SG 11202104051VA
- Authority
- SG
- Singapore
- Prior art keywords
- dystrophins
- miniaturized
- miniaturized dystrophins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862749982P | 2018-10-24 | 2018-10-24 | |
| PCT/US2019/057855 WO2020086844A1 (en) | 2018-10-24 | 2019-10-24 | Miniaturized dystrophins and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202104051VA true SG11202104051VA (en) | 2021-05-28 |
Family
ID=68582390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202104051VA SG11202104051VA (en) | 2018-10-24 | 2019-10-24 | Miniaturized dystrophins and uses thereof |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20210403947A1 (en) |
| EP (1) | EP3870202A1 (en) |
| JP (1) | JP2022505816A (en) |
| KR (1) | KR20210082193A (en) |
| CN (1) | CN113613668A (en) |
| AU (1) | AU2019368307A1 (en) |
| BR (1) | BR112021007480A2 (en) |
| CA (1) | CA3117738A1 (en) |
| CL (1) | CL2021000994A1 (en) |
| CO (1) | CO2021005083A2 (en) |
| EA (1) | EA202191123A1 (en) |
| IL (1) | IL282547A (en) |
| MX (1) | MX2021004688A (en) |
| PE (1) | PE20211110A1 (en) |
| SG (1) | SG11202104051VA (en) |
| WO (1) | WO2020086844A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021222332A1 (en) | 2020-04-29 | 2021-11-04 | Bristol-Myers Squibb Company | Miniaturized dystrophins having spectrin fusion domains and uses thereof |
| WO2022023284A1 (en) | 2020-07-27 | 2022-02-03 | Anjarium Biosciences Ag | Compositions of dna molecules, methods of making therefor, and methods of use thereof |
| US20240003898A1 (en) * | 2020-10-30 | 2024-01-04 | Pfizer Inc. | Methods for measuring dystrophin in tissue samples |
| WO2022241030A1 (en) * | 2021-05-11 | 2022-11-17 | Regenxbio Inc. | Treatment of duchenne muscular dystrophy and combinations thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| EP1366160B1 (en) | 2000-10-06 | 2008-07-09 | The Regents Of The University Of Michigan | Mini-dystrophin nucleic acid and peptide sequences |
| TWI290174B (en) | 2002-11-04 | 2007-11-21 | Advisys Inc | Synthetic muscle promoters with activities exceeding naturally occurring regulatory sequences in cardiac cells |
| US10479821B2 (en) * | 2015-01-16 | 2019-11-19 | University Of Washington | Micro-dystrophins and related methods of use |
| CA2971303A1 (en) * | 2016-06-21 | 2017-12-21 | Bamboo Therapeutics, Inc. | Optimized mini-dystrophin genes and expression cassettes and their use |
-
2019
- 2019-10-24 CA CA3117738A patent/CA3117738A1/en active Pending
- 2019-10-24 EP EP19804968.6A patent/EP3870202A1/en active Pending
- 2019-10-24 MX MX2021004688A patent/MX2021004688A/en unknown
- 2019-10-24 WO PCT/US2019/057855 patent/WO2020086844A1/en unknown
- 2019-10-24 JP JP2021522489A patent/JP2022505816A/en active Pending
- 2019-10-24 CN CN201980085325.5A patent/CN113613668A/en active Pending
- 2019-10-24 BR BR112021007480-5A patent/BR112021007480A2/en unknown
- 2019-10-24 US US17/288,029 patent/US20210403947A1/en active Pending
- 2019-10-24 SG SG11202104051VA patent/SG11202104051VA/en unknown
- 2019-10-24 AU AU2019368307A patent/AU2019368307A1/en not_active Abandoned
- 2019-10-24 EA EA202191123A patent/EA202191123A1/en unknown
- 2019-10-24 KR KR1020217015030A patent/KR20210082193A/en unknown
- 2019-10-24 PE PE2021000549A patent/PE20211110A1/en unknown
-
2021
- 2021-04-20 CL CL2021000994A patent/CL2021000994A1/en unknown
- 2021-04-21 IL IL282547A patent/IL282547A/en unknown
- 2021-04-21 CO CONC2021/0005083A patent/CO2021005083A2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2022505816A (en) | 2022-01-14 |
| CO2021005083A2 (en) | 2021-04-30 |
| IL282547A (en) | 2021-06-30 |
| CN113613668A (en) | 2021-11-05 |
| EP3870202A1 (en) | 2021-09-01 |
| AU2019368307A1 (en) | 2021-06-10 |
| CA3117738A1 (en) | 2020-04-30 |
| US20210403947A1 (en) | 2021-12-30 |
| MX2021004688A (en) | 2021-06-04 |
| KR20210082193A (en) | 2021-07-02 |
| WO2020086844A1 (en) | 2020-04-30 |
| BR112021007480A2 (en) | 2021-08-10 |
| PE20211110A1 (en) | 2021-06-17 |
| EA202191123A1 (en) | 2022-03-29 |
| CL2021000994A1 (en) | 2021-09-20 |
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