SG11202103790WA - Viral inactivation methods for continuous manufacturing of antibodies - Google Patents

Viral inactivation methods for continuous manufacturing of antibodies

Info

Publication number
SG11202103790WA
SG11202103790WA SG11202103790WA SG11202103790WA SG11202103790WA SG 11202103790W A SG11202103790W A SG 11202103790WA SG 11202103790W A SG11202103790W A SG 11202103790WA SG 11202103790W A SG11202103790W A SG 11202103790WA SG 11202103790W A SG11202103790W A SG 11202103790WA
Authority
SG
Singapore
Prior art keywords
antibodies
continuous manufacturing
viral inactivation
inactivation methods
methods
Prior art date
Application number
SG11202103790WA
Inventor
Janice Hsiu Mei Lee
Shengjiang Liu
June Zou
Original Assignee
Bayer Healthcare Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc
Publication of SG11202103790WA publication Critical patent/SG11202103790WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
    • C12N7/06Inactivation or attenuation by chemical treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16761Methods of inactivation or attenuation
    • C12N2710/16763Methods of inactivation or attenuation by chemical treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/13011Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13061Methods of inactivation or attenuation
    • C12N2740/13063Methods of inactivation or attenuation by chemical treatment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Detergent Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202103790WA 2018-11-15 2019-11-14 Viral inactivation methods for continuous manufacturing of antibodies SG11202103790WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862767652P 2018-11-15 2018-11-15
PCT/US2019/061436 WO2020102505A1 (en) 2018-11-15 2019-11-14 Viral inactivation methods for continuous manufacturing of antibodies

Publications (1)

Publication Number Publication Date
SG11202103790WA true SG11202103790WA (en) 2021-05-28

Family

ID=69024584

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202103790WA SG11202103790WA (en) 2018-11-15 2019-11-14 Viral inactivation methods for continuous manufacturing of antibodies

Country Status (14)

Country Link
EP (1) EP3880806A1 (en)
JP (1) JP7518825B2 (en)
KR (1) KR20210091709A (en)
CN (1) CN113015795B (en)
AR (1) AR117081A1 (en)
AU (1) AU2019380308A1 (en)
BR (1) BR112021006498A2 (en)
CA (1) CA3119629A1 (en)
IL (1) IL282944A (en)
MX (1) MX2021005685A (en)
PE (1) PE20211140A1 (en)
SG (1) SG11202103790WA (en)
WO (1) WO2020102505A1 (en)
ZA (1) ZA202104083B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115873810B (en) * 2022-12-26 2024-02-09 苏州良辰生物医药科技有限公司 Purification method of murine leukemia virus

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994013329A1 (en) * 1992-12-16 1994-06-23 Immuno Aktiengesellschaft Process for preparing a virus-safe biological composition
IL136552A (en) * 2000-06-05 2005-05-17 Omrix Biopharmaceuticals Ltd Method for the inactivation of viruses by a solvent - detergent combination and by nanofiltration
WO2008076371A2 (en) 2006-12-15 2008-06-26 Schering-Plough Ltd. Method for replicating influenza virus in culture
CA2808116C (en) * 2010-07-30 2016-06-07 Pfizer Inc. Tandem purification of proteins
EP3981873A1 (en) * 2012-06-29 2022-04-13 EMD Millipore Corporation Methods for inactivating viruses during a protein purification process
US10188732B2 (en) 2012-08-06 2019-01-29 Biogen Ma Inc. Methods and compositions for inactivating enveloped viruses
CN105722523B (en) 2013-11-15 2022-06-14 豪夫迈·罗氏有限公司 Virus inactivation method using environment-friendly detergent
EP4234569A3 (en) * 2014-04-15 2023-10-18 Boehringer Ingelheim International GmbH Method and use for continuously inactivating a virus during manufacture of a biological product
WO2016207328A1 (en) * 2015-06-24 2016-12-29 Glycotope Gmbh PROCESS FOR THE PURIFICATION OF γ-CARBOXYLATED POLYPEPTIDES

Also Published As

Publication number Publication date
TW202039836A (en) 2020-11-01
JP2022507369A (en) 2022-01-18
EP3880806A1 (en) 2021-09-22
CN113015795A (en) 2021-06-22
CA3119629A1 (en) 2020-05-22
CN113015795B (en) 2024-10-01
MX2021005685A (en) 2021-07-07
AR117081A1 (en) 2021-07-07
PE20211140A1 (en) 2021-06-25
ZA202104083B (en) 2023-01-25
JP7518825B2 (en) 2024-07-18
IL282944A (en) 2021-06-30
US20220002679A1 (en) 2022-01-06
BR112021006498A2 (en) 2021-07-06
KR20210091709A (en) 2021-07-22
WO2020102505A1 (en) 2020-05-22
AU2019380308A1 (en) 2021-05-13

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