SG11202103191QA - Benzimidazole derivative for use in the treatment of inflammatory disorders - Google Patents

Benzimidazole derivative for use in the treatment of inflammatory disorders

Info

Publication number
SG11202103191QA
SG11202103191QA SG11202103191QA SG11202103191QA SG11202103191QA SG 11202103191Q A SG11202103191Q A SG 11202103191QA SG 11202103191Q A SG11202103191Q A SG 11202103191QA SG 11202103191Q A SG11202103191Q A SG 11202103191QA SG 11202103191Q A SG11202103191Q A SG 11202103191QA
Authority
SG
Singapore
Prior art keywords
treatment
inflammatory disorders
benzimidazole derivative
benzimidazole
derivative
Prior art date
Application number
SG11202103191QA
Inventor
Michael Rabinowitz
Hariharan Venkatesan
Mark D Rosen
Original Assignee
Akebia Therapeutics Inc
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akebia Therapeutics Inc, Janssen Pharmaceutica Nv filed Critical Akebia Therapeutics Inc
Publication of SG11202103191QA publication Critical patent/SG11202103191QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG11202103191QA 2018-10-03 2019-10-02 Benzimidazole derivative for use in the treatment of inflammatory disorders SG11202103191QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862740748P 2018-10-03 2018-10-03
PCT/US2019/054293 WO2020072645A1 (en) 2018-10-03 2019-10-02 Benzimidazole derivative for use in the treatment of inflammatory disorders

Publications (1)

Publication Number Publication Date
SG11202103191QA true SG11202103191QA (en) 2021-04-29

Family

ID=68468802

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202103191QA SG11202103191QA (en) 2018-10-03 2019-10-02 Benzimidazole derivative for use in the treatment of inflammatory disorders

Country Status (11)

Country Link
US (1) US20210369678A1 (en)
EP (1) EP3860593A1 (en)
JP (1) JP2022504293A (en)
KR (1) KR20210100594A (en)
CN (1) CN113382729A (en)
AU (1) AU2019355097A1 (en)
CA (1) CA3114592A1 (en)
MX (1) MX2021003681A (en)
SG (1) SG11202103191QA (en)
TW (1) TW202027745A (en)
WO (1) WO2020072645A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11857543B2 (en) 2013-06-13 2024-01-02 Akebia Therapeutics, Inc. Compositions and methods for treating anemia
WO2021216530A1 (en) 2020-04-20 2021-10-28 Akebia Therapeutics, Inc. Treatment of viral infections, of organ injury, and of related conditions using a hif prolyl hydroxylase inhibitor or a hif-alpha stabilizer
WO2022150623A1 (en) 2021-01-08 2022-07-14 Akebia Therapeutics, Inc. Compounds and composition for the treatment of anemia
WO2022251563A1 (en) 2021-05-27 2022-12-01 Keryx Biopharmaceuticals, Inc. Pediatric formulations of ferric citrate
KR20230146812A (en) 2022-04-13 2023-10-20 재단법인 대구경북첨단의료산업진흥재단 Composition for treating inflammatory bowel disease comprising an arylethene derivative as an active ingredient

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0911444B8 (en) 2008-04-28 2021-05-25 Janssen Pharmaceutica Nv benzoimidazoles as prolyl hydroxylase inhibitors and pharmaceutical composition comprising them

Also Published As

Publication number Publication date
EP3860593A1 (en) 2021-08-11
CA3114592A1 (en) 2020-04-09
CN113382729A (en) 2021-09-10
TW202027745A (en) 2020-08-01
WO2020072645A1 (en) 2020-04-09
JP2022504293A (en) 2022-01-13
MX2021003681A (en) 2021-08-19
US20210369678A1 (en) 2021-12-02
KR20210100594A (en) 2021-08-17
AU2019355097A1 (en) 2021-05-27

Similar Documents

Publication Publication Date Title
IL273693A (en) Treatment of inflammatory disorders
IL268211A (en) Cannabinoid-containing complex mixtures for the treatment of mast cell-associated or basophil-mediated inflammatory disorders
MX2018005694A (en) 2-(1h-indazol-3-yl)-3h-imidazo[4,5-c]pyridines and their anti-inflammatory uses thereof.
SG11202103191QA (en) Benzimidazole derivative for use in the treatment of inflammatory disorders
HK1258914A1 (en) Use of 2-substituted indazoles for the treatment and prophylaxis of autoimmune diseases
HRP20181332T1 (en) Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
GB201402070D0 (en) Pharmaceutical compositions for the treatment of inflammatory disorders
IL284125A (en) Quinoline derivatives for use in the treatment of inflammation diseases
HK1257169A1 (en) Indolin-2-one derivatives for use in the treatment of cns and related disorders
SG11201708181RA (en) Methods for the treatment of inflammatory disorders
IL246855A0 (en) Agents for use in the treatment of retinal inflammation
IL292690A (en) Mrgprx2 antagonists for the treatment of inflammatory disorders
IL275349A (en) Use of hm4di in the treatment of seizure disorders
IL260987A (en) Treatment and diagnosis of inflammatory disorders
ZA202006886B (en) R-fadrozole for use in the treatment of aldostonerism
ZA201806894B (en) (+)-azasetron for use in the treatment of ear disorders
EP3371154A4 (en) Heterocycle derivatives and their use for the treatment of cns disorders
IL276697A (en) 3beta-(4-methoxybenzyloxy)pregn-5-en-20-one for use in the treatment of cannabinoids-related disorders
PT3442537T (en) (+)-azasetron for use in the treatment of ear disorders
GB201521543D0 (en) Methods for the treatment of inflammatory disorders
PT3370727T (en) Non-bioconvertible c3-substituted pregnenolone derivatives for use in the treatment of substance use disorders
GB201513993D0 (en) Methods for the treatment of inflammatory disorders
GB201513345D0 (en) Methods for the treatment of Inflammatory disorders
GB201507113D0 (en) Methods for the treatment of inflammatory disorders
GB201506419D0 (en) Methods for the treatment of inflammatory disorders