SG11202103111TA - Ssi cells with predictable and stable transgene expression and methods of formation - Google Patents
Ssi cells with predictable and stable transgene expression and methods of formationInfo
- Publication number
- SG11202103111TA SG11202103111TA SG11202103111TA SG11202103111TA SG11202103111TA SG 11202103111T A SG11202103111T A SG 11202103111TA SG 11202103111T A SG11202103111T A SG 11202103111TA SG 11202103111T A SG11202103111T A SG 11202103111TA SG 11202103111T A SG11202103111T A SG 11202103111TA
- Authority
- SG
- Singapore
- Prior art keywords
- predictable
- formation
- methods
- transgene expression
- stable transgene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862739546P | 2018-10-01 | 2018-10-01 | |
| PCT/US2019/054045 WO2020072480A1 (en) | 2018-10-01 | 2019-10-01 | Ssi cells with predictable and stable transgene expression and methods of formation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202103111TA true SG11202103111TA (en) | 2021-04-29 |
Family
ID=68290359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202103111TA SG11202103111TA (en) | 2018-10-01 | 2019-10-01 | Ssi cells with predictable and stable transgene expression and methods of formation |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220049275A1 (en) |
| EP (1) | EP3844288A1 (en) |
| JP (1) | JP2022513319A (en) |
| CN (1) | CN113227388A (en) |
| SG (1) | SG11202103111TA (en) |
| WO (1) | WO2020072480A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112365920B (en) * | 2020-09-30 | 2024-04-02 | 中国农业科学院蜜蜂研究所 | Method for identifying bee differentiation key genes, identified genes and application |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1258959B (en) | 1992-06-09 | 1996-03-11 | MOBILE MODULES PLANT FOR THE DEVELOPMENT AND PRODUCTION OF BIOTECHNOLOGICAL PRODUCTS ON A PILOT SCALE | |
| WO1998041645A1 (en) * | 1997-03-14 | 1998-09-24 | Idec Pharmaceuticals Corporation | Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same |
| EP1276865B1 (en) * | 2000-04-28 | 2014-05-21 | Sangamo BioSciences, Inc. | Methods for binding an exogenous molecule to cellular chromatin |
| CN1942840B (en) | 2004-02-03 | 2012-08-22 | 艾克塞勒雷克斯公司 | System and method for manufacturing |
| US7629167B2 (en) | 2004-06-04 | 2009-12-08 | Xcellerex, Inc. | Disposable bioreactor systems and methods |
| WO2007067656A2 (en) | 2005-12-05 | 2007-06-14 | Hope Ernest G | Prevalidated, modular good manufacturing practice-compliant facility |
| PL2137655T3 (en) | 2007-04-16 | 2012-12-31 | Momenta Pharmaceuticals Inc | Defined glycoprotein products and related methods |
| EP3176263A1 (en) * | 2007-08-10 | 2017-06-07 | Toto Ltd. | Method of producing recombinant mammalian cells |
| WO2011139708A2 (en) | 2010-04-26 | 2011-11-10 | Toyota Motor Engineering & Manufacturing North America, Inc. | Improved hydrogen release from complex metal hydrides by solvation in ionic liquids |
| BR112012030522A2 (en) * | 2010-05-27 | 2020-10-13 | Heinrich-Pette-Institut Leibniz-Institut Fur Experimentelle Virologie - Stiftung Burgerlichen Rechts | METHOD FOR THE PREPARATION OF AN EXPRESSION VECTOR THAT CODES A CONFIGURED RECOMBINASE, METHOD FOR THE PREPARATION OF A TRANSFORMED CELL, NUCLEIC ACID, CONFIGURED RECOMBINASE ENCODED BY NUCLEIC ACID, TRANSFORMED COMMODIC CYCLE "EFFECT" |
| US10371394B2 (en) | 2010-09-20 | 2019-08-06 | Biologics Modular Llc | Mobile, modular cleanroom facility |
| US9388373B2 (en) | 2011-03-08 | 2016-07-12 | University Of Maryland Baltimore County | Microscale bioprocessing system and method for protein manufacturing |
| EP2711428A1 (en) * | 2012-09-21 | 2014-03-26 | Lonza Biologics plc. | Site-specific integration |
| CN104884467A (en) * | 2012-12-18 | 2015-09-02 | 诺华股份有限公司 | Production of therapeutic proteins in genetically modified mammalian cells |
| EP4321628A2 (en) | 2013-05-23 | 2024-02-14 | The Board of Trustees of the Leland Stanford Junior University | Transposition into native chromatin for personal epigenomics |
| GB2517936B (en) | 2013-09-05 | 2016-10-19 | Babraham Inst | Chromosome conformation capture method including selection and enrichment steps |
| US20170130247A1 (en) * | 2015-09-30 | 2017-05-11 | Whitehead Institute For Biomedical Research | Compositions and methods for altering gene expression |
| MX2019008227A (en) * | 2017-01-10 | 2020-08-17 | Juno Therapeutics Inc | Epigenetic analysis of cell therapy and related methods. |
| CN110914413A (en) * | 2017-02-17 | 2020-03-24 | 隆萨有限公司 | Mammalian cell producing adeno-associated virus |
| EP3583121A1 (en) * | 2017-02-17 | 2019-12-25 | Lonza Ltd | Multi-site specific integration cells for difficult to express proteins |
-
2019
- 2019-10-01 CN CN201980064770.3A patent/CN113227388A/en active Pending
- 2019-10-01 WO PCT/US2019/054045 patent/WO2020072480A1/en unknown
- 2019-10-01 EP EP19790369.3A patent/EP3844288A1/en active Pending
- 2019-10-01 US US17/278,866 patent/US20220049275A1/en active Pending
- 2019-10-01 SG SG11202103111TA patent/SG11202103111TA/en unknown
- 2019-10-01 JP JP2021542082A patent/JP2022513319A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3844288A1 (en) | 2021-07-07 |
| US20220049275A1 (en) | 2022-02-17 |
| WO2020072480A1 (en) | 2020-04-09 |
| CN113227388A (en) | 2021-08-06 |
| JP2022513319A (en) | 2022-02-07 |
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