SG11202102689UA - Methods for differentiating mesenchymal stem cells - Google Patents
Methods for differentiating mesenchymal stem cellsInfo
- Publication number
- SG11202102689UA SG11202102689UA SG11202102689UA SG11202102689UA SG11202102689UA SG 11202102689U A SG11202102689U A SG 11202102689UA SG 11202102689U A SG11202102689U A SG 11202102689UA SG 11202102689U A SG11202102689U A SG 11202102689UA SG 11202102689U A SG11202102689U A SG 11202102689UA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- stem cells
- mesenchymal stem
- differentiating mesenchymal
- differentiating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/90—Polysaccharides
- C12N2501/91—Heparin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1353—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from bone marrow mesenchymal stem cells (BM-MSC)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18196717 | 2018-09-25 | ||
EP19169084 | 2019-04-12 | ||
PCT/EP2019/075790 WO2020064791A1 (en) | 2018-09-25 | 2019-09-25 | Methods for differentiating mesenchymal stem cells |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202102689UA true SG11202102689UA (en) | 2021-04-29 |
Family
ID=68172158
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202102689UA SG11202102689UA (en) | 2018-09-25 | 2019-09-25 | Methods for differentiating mesenchymal stem cells |
Country Status (13)
Country | Link |
---|---|
US (1) | US20210395686A1 (en) |
EP (1) | EP3856894B1 (en) |
JP (1) | JP2022501053A (en) |
KR (1) | KR20210074303A (en) |
CN (1) | CN113056557A (en) |
AU (1) | AU2019345976A1 (en) |
BE (1) | BE1026595B9 (en) |
BR (1) | BR112021005697A2 (en) |
CA (1) | CA3112636A1 (en) |
IL (1) | IL281751A (en) |
MX (1) | MX2021003383A (en) |
SG (1) | SG11202102689UA (en) |
WO (1) | WO2020064791A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3202264A1 (en) * | 2020-10-08 | 2022-04-14 | Hyun Sook Park | Osteoblasts differentiated from mesenchymal stem cells and composition for treating bone disease comprising the same |
CN113789333B (en) * | 2021-09-07 | 2023-07-14 | 中国人民解放军军事科学院军事医学研究院 | Application of Chi3l1 in regulating and controlling hUC-MSCs to inhibit Th17 differentiation-mediated immunoregulation |
CN115349515A (en) * | 2022-08-02 | 2022-11-18 | 华院计算技术(上海)股份有限公司 | Cell preservation solution and cell preservation method |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4764369A (en) | 1983-07-14 | 1988-08-16 | New York Blood Center Inc. | Undenatured virus-free biologically active protein derivatives |
US5837539A (en) | 1990-11-16 | 1998-11-17 | Osiris Therapeutics, Inc. | Monoclonal antibodies for human mesenchymal stem cells |
US5811094A (en) | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
US5972703A (en) | 1994-08-12 | 1999-10-26 | The Regents Of The University Of Michigan | Bone precursor cells: compositions and methods |
US5736396A (en) | 1995-01-24 | 1998-04-07 | Case Western Reserve University | Lineage-directed induction of human mesenchymal stem cell differentiation |
US5827740A (en) | 1996-07-30 | 1998-10-27 | Osiris Therapeutics, Inc. | Adipogenic differentiation of human mesenchymal stem cells |
WO2000007639A1 (en) | 1998-08-07 | 2000-02-17 | Tissue Engineering, Inc. | Bone precursor compositions |
US7687505B2 (en) * | 2002-01-14 | 2010-03-30 | Board Of Trustees Of The University Of Illinois | Use of modified pyrimidine compounds to promote stem cell migration and proliferation |
KR20080109726A (en) | 2006-02-16 | 2008-12-17 | 유니베르시테 리브레 드 브룩크젤즈 | A method for osteogenic differentiation of bone marrow stem cells (bmsc) and uses thereof |
WO2008129563A2 (en) * | 2007-04-23 | 2008-10-30 | Stempeutics Research Private Limited, | Human mesenchymal stem cells and preparation thereof |
US20100278788A1 (en) | 2008-01-11 | 2010-11-04 | Bone Therapeutics, S.A. | Osteogenic Differentiation Of Bone Marrow Stem Cells And Mesenchymal Stem Cells Using A Combination Of Growth Factors |
EP2403550A2 (en) * | 2008-11-24 | 2012-01-11 | BioE LLC | Implantable compositions for repairing osteochondral defects |
EP2766475A1 (en) * | 2011-10-11 | 2014-08-20 | Bone Therapeutics S.A. | Uses of growth and differentiation factor 8 (gdf-8) |
WO2014093836A1 (en) * | 2012-12-13 | 2014-06-19 | University Of Georgia Research Foundation, Inc. | Ossification-inducing composition and methods of use thereof |
JP6446222B2 (en) * | 2014-09-30 | 2018-12-26 | 株式会社ジーシー | Cartilage differentiation culture medium and method for producing cartilage tissue |
CA3079439C (en) * | 2017-10-20 | 2022-08-09 | Bone Therapeutics Sa | Methods for differentiating mesenchymal stem cells |
-
2019
- 2019-09-25 CA CA3112636A patent/CA3112636A1/en active Pending
- 2019-09-25 BE BE20195629A patent/BE1026595B9/en active IP Right Grant
- 2019-09-25 CN CN201980075918.3A patent/CN113056557A/en active Pending
- 2019-09-25 MX MX2021003383A patent/MX2021003383A/en unknown
- 2019-09-25 JP JP2021516816A patent/JP2022501053A/en active Pending
- 2019-09-25 WO PCT/EP2019/075790 patent/WO2020064791A1/en active Application Filing
- 2019-09-25 US US17/278,938 patent/US20210395686A1/en active Pending
- 2019-09-25 BR BR112021005697-1A patent/BR112021005697A2/en unknown
- 2019-09-25 SG SG11202102689UA patent/SG11202102689UA/en unknown
- 2019-09-25 AU AU2019345976A patent/AU2019345976A1/en active Pending
- 2019-09-25 KR KR1020217011782A patent/KR20210074303A/en unknown
- 2019-09-25 EP EP19769366.6A patent/EP3856894B1/en active Active
-
2021
- 2021-03-23 IL IL281751A patent/IL281751A/en unknown
Also Published As
Publication number | Publication date |
---|---|
BE1026595B1 (en) | 2020-10-28 |
JP2022501053A (en) | 2022-01-06 |
IL281751A (en) | 2021-05-31 |
CA3112636A1 (en) | 2020-04-02 |
BE1026595B9 (en) | 2020-11-03 |
CN113056557A (en) | 2021-06-29 |
EP3856894C0 (en) | 2023-08-02 |
KR20210074303A (en) | 2021-06-21 |
EP3856894A1 (en) | 2021-08-04 |
MX2021003383A (en) | 2021-10-26 |
BR112021005697A2 (en) | 2021-06-22 |
BE1026595A1 (en) | 2020-04-01 |
WO2020064791A1 (en) | 2020-04-02 |
EP3856894B1 (en) | 2023-08-02 |
US20210395686A1 (en) | 2021-12-23 |
AU2019345976A1 (en) | 2021-05-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL250340A0 (en) | Media for culturing pluripotent stem cells | |
EP3384007A4 (en) | Improved methods for reprograming non-pluripotent cells into pluripotent stem cells | |
EP3453753A4 (en) | Method for subculturing pluripotent stem cells | |
IL281751A (en) | Methods for differentiating mesenchymal stem cells | |
SG11201706886PA (en) | Cell culture method for mesenchymal stem cells | |
HK1247639A1 (en) | Medium composition for culturing stem cells | |
IL257678A (en) | Methods for stem cell transplantation | |
IL249170A0 (en) | Method for preparing induced pluripotency stem cells from mesenchymal stem cells by using phlorotannin fraction | |
IL279172A (en) | Methods for generating hematopoietic stem cells | |
IL273987B (en) | Methods for differentiating mesenchymal stem cells | |
EP3064574A4 (en) | Method for differentiating pluripotent stem cell induced from mesenchymal stem cell into chondrocyte | |
EP3202896A4 (en) | Method for culturing pluripotent stem cells | |
EP3184627A4 (en) | Culture medium for mesenchymal stem cells | |
PL3436568T3 (en) | Culture medium for pluripotent stem cells | |
EP3385368A4 (en) | Method for producing mesenchymal stem cells | |
EP3508569A4 (en) | Method for obtaining microglia from pluripotent stem cells | |
HK1216260A1 (en) | Method for preparing clinical-grade placental mesenchymal stem cells | |
EP3227682A4 (en) | Method of distinguishing mesenchymal stem cells | |
HK1254737A1 (en) | Stem cell culturing method | |
AU2018903629A0 (en) | Mesenchymal stem cells | |
EP3651779A4 (en) | Methods for generating pluripotent stem cells | |
EP3672590A4 (en) | Methods for inducing hematopoietic stem cell specificity | |
EP3448983A4 (en) | Culture media for multipotent stem cells | |
AU2014903390A0 (en) | A method for culturing mesenchymal stem cells | |
SG10201800796XA (en) | Method of distinguishing mesenchymal stem cells |