SG11202102653WA - Rotomeric isomers of 4-alkyl-5-heteroaryl-3h-1,2- dithiole-3-thiones - Google Patents

Rotomeric isomers of 4-alkyl-5-heteroaryl-3h-1,2- dithiole-3-thiones

Info

Publication number
SG11202102653WA
SG11202102653WA SG11202102653WA SG11202102653WA SG11202102653WA SG 11202102653W A SG11202102653W A SG 11202102653WA SG 11202102653W A SG11202102653W A SG 11202102653WA SG 11202102653W A SG11202102653W A SG 11202102653WA SG 11202102653W A SG11202102653W A SG 11202102653WA
Authority
SG
Singapore
Prior art keywords
dithiole
thiones
heteroaryl
alkyl
rotomeric
Prior art date
Application number
SG11202102653WA
Inventor
Bomi Framroze
Original Assignee
St Ip Holding Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Ip Holding Ag filed Critical St Ip Holding Ag
Publication of SG11202102653WA publication Critical patent/SG11202102653WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/18Antioxidants, e.g. antiradicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62Three oxygen atoms, e.g. ascorbic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Toxicology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG11202102653WA 2018-09-18 2019-09-17 Rotomeric isomers of 4-alkyl-5-heteroaryl-3h-1,2- dithiole-3-thiones SG11202102653WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862732867P 2018-09-18 2018-09-18
PCT/IB2019/001138 WO2020058767A1 (en) 2018-09-18 2019-09-17 Rotomeric isomers of 4-alkyl-5-heteroaryl-3h-1,2- dithiole-3-thiones

Publications (1)

Publication Number Publication Date
SG11202102653WA true SG11202102653WA (en) 2021-04-29

Family

ID=69024428

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202102653WA SG11202102653WA (en) 2018-09-18 2019-09-17 Rotomeric isomers of 4-alkyl-5-heteroaryl-3h-1,2- dithiole-3-thiones

Country Status (13)

Country Link
US (1) US20210206751A1 (en)
EP (1) EP3853223A1 (en)
JP (1) JP2022501424A (en)
KR (1) KR20210061390A (en)
CN (2) CN113166127A (en)
AU (1) AU2019341666A1 (en)
BR (1) BR112021005010A2 (en)
CA (1) CA3113169A1 (en)
EA (1) EA202190798A1 (en)
IL (1) IL281598A (en)
MX (1) MX2021003123A (en)
SG (1) SG11202102653WA (en)
WO (1) WO2020058767A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202200144A (en) * 2020-03-16 2022-01-01 瑞士商St知識產權控股公司 Rotomeric isomers of 4-alkyl-5-heteroaryl-3h-1,2-dithiole-3-thiones
DE202023001038U1 (en) 2023-05-10 2023-06-16 Rainer Teutenberg Ballistic and acoustically effective clothing for shooting ranges

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3156369A (en) 1962-09-19 1964-11-10 Ethicon Inc Bicameral container
IT1292677B1 (en) 1997-02-28 1999-02-11 Bormioli Metalplast Spa PACKAGING TO KEEP THE PRODUCTS SEPARATE BEFORE USE.
TW200640898A (en) * 2005-02-24 2006-12-01 Solvay Pharm Bv Anethole dithiolethione and other dithiolethiones for the treatment of conditions associated with dysfunction of monoamine neurotransmission
WO2007010560A1 (en) 2005-07-15 2007-01-25 Bormioli Rocco & Figlio S.P.A. A reservoir with a cutter for substances to be mixed with liquids at moment of use, in particular for single-dose containers
WO2007121356A2 (en) * 2006-04-13 2007-10-25 Accu-Break Technologies Method of treatment with predictably breakable pharmaceutical tablets
GB0704718D0 (en) * 2007-03-12 2007-04-18 Prendergast Patrick T Compounds and methods for preventing and treating mucositis
ES2527604T3 (en) 2010-02-16 2015-01-27 Teva Branded Pharmaceutical Products R & D, Inc. An inhalable pharmaceutical composition
RU2019110128A (en) 2012-02-28 2019-05-08 Айсьютика Холдингз Инк. Бви INHALATION PHARMACEUTICAL COMPOSITIONS
AU2014261538A1 (en) 2013-04-29 2015-12-10 Sanofi Sa Inhalable pharmaceutical compositions and the inhaler devices containing them
WO2016207914A2 (en) 2015-06-25 2016-12-29 St Ip Holding Ag Methods for preparing oltipraz
CN105327337A (en) * 2015-10-30 2016-02-17 中国人民解放军96617部队 Anti-radiation anti-caries inflammation-diminishing oral preparation
WO2018047013A1 (en) * 2016-09-12 2018-03-15 St Ip Holding Ag Formulations of 4-methyl-5-(pyrazin-2-yl)-3h-1, 2-dithiole-3-thione, and methods of making and using same
WO2018047002A1 (en) * 2016-09-12 2018-03-15 St Ip Holding Ag Formulations of 4-methyl-5-(pyrazin-2-yl)-3h-1.2-dithiole-3-thione, taste-modified formulations, and methods of making and using same

Also Published As

Publication number Publication date
AU2019341666A1 (en) 2021-05-13
IL281598A (en) 2021-05-31
MX2021003123A (en) 2021-08-11
KR20210061390A (en) 2021-05-27
US20210206751A1 (en) 2021-07-08
JP2022501424A (en) 2022-01-06
CA3113169A1 (en) 2020-03-26
CN113166127A (en) 2021-07-23
EP3853223A1 (en) 2021-07-28
WO2020058767A4 (en) 2020-06-04
EA202190798A1 (en) 2021-09-10
CN113694068A (en) 2021-11-26
WO2020058767A1 (en) 2020-03-26
BR112021005010A2 (en) 2021-06-08

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