SG11202102290RA - Herv-k-derived antigens as shared tumor antigens for anti-cancer vaccine - Google Patents

Herv-k-derived antigens as shared tumor antigens for anti-cancer vaccine

Info

Publication number
SG11202102290RA
SG11202102290RA SG11202102290RA SG11202102290RA SG11202102290RA SG 11202102290R A SG11202102290R A SG 11202102290RA SG 11202102290R A SG11202102290R A SG 11202102290RA SG 11202102290R A SG11202102290R A SG 11202102290RA SG 11202102290R A SG11202102290R A SG 11202102290RA
Authority
SG
Singapore
Prior art keywords
antigens
herv
cancer vaccine
shared tumor
derived
Prior art date
Application number
SG11202102290RA
Inventor
Stéphane Depil
Laurie Tonon
Christophe Caux
Paola Bonaventura
Jenny Valladeau
Original Assignee
Centre Leon Berard
Univ Claude Bernard Lyon
Centre Nat Rech Scient
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Leon Berard, Univ Claude Bernard Lyon, Centre Nat Rech Scient, Inst Nat Sante Rech Med filed Critical Centre Leon Berard
Publication of SG11202102290RA publication Critical patent/SG11202102290RA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/80—Vaccine for a specifically defined cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
SG11202102290RA 2018-09-06 2019-09-06 Herv-k-derived antigens as shared tumor antigens for anti-cancer vaccine SG11202102290RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18306173 2018-09-06
PCT/EP2019/073883 WO2020049169A1 (en) 2018-09-06 2019-09-06 Herv-k-derived antigens as shared tumor antigens for anti-cancer vaccine

Publications (1)

Publication Number Publication Date
SG11202102290RA true SG11202102290RA (en) 2021-04-29

Family

ID=63683819

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202102290RA SG11202102290RA (en) 2018-09-06 2019-09-06 Herv-k-derived antigens as shared tumor antigens for anti-cancer vaccine

Country Status (12)

Country Link
US (1) US20210330774A1 (en)
EP (1) EP3846839A1 (en)
JP (1) JP2021536479A (en)
KR (1) KR20210055725A (en)
CN (1) CN112867502A (en)
AU (1) AU2019334676A1 (en)
BR (1) BR112021004244A2 (en)
CA (1) CA3111663A1 (en)
IL (1) IL281253B1 (en)
MX (1) MX2021002519A (en)
SG (1) SG11202102290RA (en)
WO (1) WO2020049169A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202000006973A1 (en) 2020-04-02 2021-10-02 Istituto Naz Tumori Irccs Fondazione G Pascale TUMOR-SPECIFIC HERV ANTIGENS AND THEIR USE IN CANCER IMMUNOTHERAPY
US11791123B2 (en) 2021-04-29 2023-10-17 Electronics And Telecommunications Research Institute X-ray tube
WO2023144231A1 (en) 2022-01-25 2023-08-03 Ervaccine Technologies New method for identifying herv-derived epitopes
WO2023242343A1 (en) 2022-06-15 2023-12-21 Immunoscape Pte. Ltd. Human t cell receptors specific for antigenic peptides derived from mitogen-activated protein kinase 8 interacting protein 2 (mapk8ip2), epstein-barr virus or human endogenous retrovirus, and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554101A (en) 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4866034A (en) 1982-05-26 1989-09-12 Ribi Immunochem Research Inc. Refined detoxified endotoxin
US4797368A (en) 1985-03-15 1989-01-10 The United States Of America As Represented By The Department Of Health And Human Services Adeno-associated virus as eukaryotic expression vector
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
US4950645A (en) 1988-07-08 1990-08-21 Immunotherapeutics, Inc. Composition for macrophage activation
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
US5994136A (en) 1997-12-12 1999-11-30 Cell Genesys, Inc. Method and means for producing high titer, safe, recombinant lentivirus vectors
WO2003106634A2 (en) * 2002-06-13 2003-12-24 Chiron Corporation Vectors for expression of hml-2 polypeptides
AU2003276679A1 (en) * 2002-06-13 2003-12-31 Chiron Corporation Vectors for expression of hml-2 polypeptides
WO2006103562A2 (en) * 2005-03-30 2006-10-05 Centre National De La Recherche Scientifique (Cnrs) Endogenous retrovirus and proteins encoded by env gene as a target for cancer treatment
US20080171061A1 (en) * 2006-07-21 2008-07-17 Douglas Nixon Human endogenous retrovirus polypeptide compositions and methods of use thereof

Also Published As

Publication number Publication date
AU2019334676A1 (en) 2021-04-01
JP2021536479A (en) 2021-12-27
IL281253B1 (en) 2024-03-01
US20210330774A1 (en) 2021-10-28
IL281253A (en) 2021-04-29
MX2021002519A (en) 2021-06-18
CA3111663A1 (en) 2020-03-12
CN112867502A (en) 2021-05-28
WO2020049169A1 (en) 2020-03-12
BR112021004244A2 (en) 2021-05-25
KR20210055725A (en) 2021-05-17
EP3846839A1 (en) 2021-07-14

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