SG11202102149SA - Methods of treating mycobacterial infections using tetracycline compounds - Google Patents

Methods of treating mycobacterial infections using tetracycline compounds

Info

Publication number
SG11202102149SA
SG11202102149SA SG11202102149SA SG11202102149SA SG11202102149SA SG 11202102149S A SG11202102149S A SG 11202102149SA SG 11202102149S A SG11202102149S A SG 11202102149SA SG 11202102149S A SG11202102149S A SG 11202102149SA SG 11202102149S A SG11202102149S A SG 11202102149SA
Authority
SG
Singapore
Prior art keywords
methods
tetracycline compounds
mycobacterial infections
treating mycobacterial
treating
Prior art date
Application number
SG11202102149SA
Inventor
Michael Cynamon
Michael Draper
Judith Steenbergen
S Tanaka
Original Assignee
Paratek Pharm Innc
Us Gov Veterans Affairs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paratek Pharm Innc, Us Gov Veterans Affairs filed Critical Paratek Pharm Innc
Publication of SG11202102149SA publication Critical patent/SG11202102149SA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/08Antibacterial agents for leprosy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG11202102149SA 2018-09-04 2019-09-03 Methods of treating mycobacterial infections using tetracycline compounds SG11202102149SA (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862726738P 2018-09-04 2018-09-04
US201862731410P 2018-09-14 2018-09-14
US201862746039P 2018-10-16 2018-10-16
US201862760131P 2018-11-13 2018-11-13
PCT/US2019/049368 WO2020051151A1 (en) 2018-09-04 2019-09-03 Methods of treating mycobacterial infections using tetracycline compounds

Publications (1)

Publication Number Publication Date
SG11202102149SA true SG11202102149SA (en) 2021-04-29

Family

ID=69722600

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202102149SA SG11202102149SA (en) 2018-09-04 2019-09-03 Methods of treating mycobacterial infections using tetracycline compounds

Country Status (13)

Country Link
US (1) US20210346408A1 (en)
EP (1) EP3846805A4 (en)
JP (1) JP7466544B2 (en)
KR (1) KR20210090160A (en)
CN (1) CN113164456A (en)
AU (1) AU2019335203A1 (en)
BR (1) BR112021004057A2 (en)
CA (1) CA3111447A1 (en)
MA (1) MA53564A (en)
MX (1) MX2021002503A (en)
PH (1) PH12021550452A1 (en)
SG (1) SG11202102149SA (en)
WO (1) WO2020051151A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021288202A1 (en) * 2020-06-11 2022-12-08 Paratek Pharmaceuticals Inc. Crystalline forms of omadacycline, methods of synthesis thereof and methods of use thereof
WO2022119899A1 (en) * 2020-12-02 2022-06-09 Shionogi & Co., Ltd. A medicament for treating mycobacterial infection characterized by combining a cytochrome bc1 inhibitor with clarithromycin or azithromycin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1301467T1 (en) * 2000-07-07 2007-02-28 Tufts College 9-substituted minocycline compounds
US20060194773A1 (en) * 2001-07-13 2006-08-31 Paratek Pharmaceuticals, Inc. Tetracyline compounds having target therapeutic activities
PT2271348T (en) * 2008-03-28 2018-04-16 Paratek Pharm Innc Oral tablet formulation of tetracycline compound
SG11201808246SA (en) * 2016-03-24 2018-10-30 Paratek Pharm Innc Methods for treating and preventing c. difficile infection
CN109414445A (en) * 2016-05-02 2019-03-01 帕拉特克药品公司 9- Aminomethyl Minocycline compound and its application method in urethral infection (UTI) treatment
TWI746610B (en) * 2016-08-03 2021-11-21 美商派瑞泰Spv2有限公司 9-aminomethyl minocycline compounds and uses thereof
GB201615693D0 (en) * 2016-09-15 2016-11-02 Combinatorx Infection Ltd Combinations

Also Published As

Publication number Publication date
BR112021004057A2 (en) 2021-05-25
AU2019335203A1 (en) 2021-05-06
JP7466544B2 (en) 2024-04-12
EP3846805A4 (en) 2022-08-24
JP2021536504A (en) 2021-12-27
MA53564A (en) 2021-07-14
CA3111447A1 (en) 2020-03-12
US20210346408A1 (en) 2021-11-11
CN113164456A (en) 2021-07-23
MX2021002503A (en) 2021-06-15
KR20210090160A (en) 2021-07-19
EP3846805A1 (en) 2021-07-14
PH12021550452A1 (en) 2021-12-06
WO2020051151A1 (en) 2020-03-12

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