SG11202101905YA - Vitamin d pediatric dosage forms, methods of making and using - Google Patents

Vitamin d pediatric dosage forms, methods of making and using

Info

Publication number
SG11202101905YA
SG11202101905YA SG11202101905YA SG11202101905YA SG11202101905YA SG 11202101905Y A SG11202101905Y A SG 11202101905YA SG 11202101905Y A SG11202101905Y A SG 11202101905YA SG 11202101905Y A SG11202101905Y A SG 11202101905YA SG 11202101905Y A SG11202101905Y A SG 11202101905YA
Authority
SG
Singapore
Prior art keywords
vitamin
making
methods
dosage forms
pediatric dosage
Prior art date
Application number
SG11202101905YA
Inventor
Praful Balavant Deshpande
Stephen James Quinlan
Marta Golec
John Gerard O'brien
James Joseph Mcdonald
Reem Elamein Elsiddig
Ken O'shea
Original Assignee
Opko Ireland Global Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opko Ireland Global Holdings Ltd filed Critical Opko Ireland Global Holdings Ltd
Publication of SG11202101905YA publication Critical patent/SG11202101905YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5929,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
SG11202101905YA 2018-08-31 2019-08-30 Vitamin d pediatric dosage forms, methods of making and using SG11202101905YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862725940P 2018-08-31 2018-08-31
PCT/IB2019/057360 WO2020044314A1 (en) 2018-08-31 2019-08-30 Vitamin d pediatric dosage forms, methods of making and using

Publications (1)

Publication Number Publication Date
SG11202101905YA true SG11202101905YA (en) 2021-03-30

Family

ID=68165642

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202101905YA SG11202101905YA (en) 2018-08-31 2019-08-30 Vitamin d pediatric dosage forms, methods of making and using

Country Status (21)

Country Link
US (3) US11000480B2 (en)
EP (1) EP3843706A1 (en)
JP (1) JP2021535155A (en)
KR (1) KR20210054539A (en)
CN (1) CN112912067A (en)
AU (3) AU2019329905B2 (en)
BR (1) BR112021003788A2 (en)
CA (1) CA3110020A1 (en)
CL (2) CL2021000493A1 (en)
CO (1) CO2021003805A2 (en)
CR (1) CR20210158A (en)
DE (1) DE202019005769U1 (en)
EA (1) EA202190633A1 (en)
EC (1) ECSP21021189A (en)
IL (1) IL280937A (en)
MX (1) MX2020011740A (en)
PE (1) PE20211489A1 (en)
PH (1) PH12021550413A1 (en)
SG (1) SG11202101905YA (en)
TW (1) TW202034905A (en)
WO (1) WO2020044314A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220164539A (en) 2020-04-06 2022-12-13 에어젠 파마 엘티디. 25-hydroxyvitamin D for the treatment of SARS-CoV-2 infection
CA3181945A1 (en) 2020-05-31 2021-12-09 Eirgen Pharma Ltd. Hard capsule dosage form and uses thereof
US11672761B2 (en) 2020-11-16 2023-06-13 Orcosa Inc. Rapidly infusing platform and compositions for therapeutic treatment in humans
CN114176164A (en) * 2021-12-17 2022-03-15 广东驱动力生物科技股份有限公司 Water-soluble anti-stress additive for ruminants

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59155309A (en) * 1983-02-22 1984-09-04 Teijin Ltd Active type vitamin d3 composition and its preparation
ES2094290T3 (en) * 1991-04-09 1997-01-16 Takeda Chemical Industries Ltd STABILIZED PREPARATION OF VITAMIN D.
ATE211387T1 (en) * 1992-06-22 2002-01-15 Bone Care Int Inc ORAL 1ALPHA-HYDROXYPREVITAMIN D
US7632518B2 (en) * 2002-01-15 2009-12-15 Dsm Ip Assets B.V. 25-hydroxy vitamin D3 compositions
SI3095447T1 (en) * 2006-02-03 2022-02-28 Opko Renal, Llc Treating vitamin d insufficiency and deficiency with 25-hydroxyvitamin d2 and 25-hydroxyvitamin d3
PL2148661T3 (en) 2007-04-25 2013-07-31 Cytochroma Inc Oral controlled release compositions comprising vitamin d compound and waxy carrier
CN101584683A (en) * 2009-06-12 2009-11-25 沈阳药科大学 Metolazone slow-release capsule and method for preparing same
WO2012047098A1 (en) * 2010-10-04 2012-04-12 Dishman Pharmaceuticals And Chemicals Ltd. Encapsulated fat-soluble vitamin
US9907758B2 (en) * 2012-01-09 2018-03-06 Panjab University Department Of Biotechnology (Dbt) Process for preparing solid lipid sustained release nanoparticles for delivery of vitamins
KR101847947B1 (en) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 Stabilized modified release vitamin d formulation
US20160008377A1 (en) * 2014-07-12 2016-01-14 Aphios Corporation Formulations and compositions of vitamin d analogs for treating and preventing cancer and other diseases
CN114681468A (en) * 2014-08-07 2022-07-01 欧普科爱尔兰环球控股有限公司 Adjunctive therapy with 25-hydroxyvitamin D
CN108420797B (en) * 2018-05-09 2022-05-03 南京海融制药有限公司 Vitamin D analogue preparation and preparation method thereof

Also Published As

Publication number Publication date
MX2020011740A (en) 2021-04-19
AU2021107174A4 (en) 2021-12-09
IL280937A (en) 2021-04-29
JP2021535155A (en) 2021-12-16
AU2021107168A4 (en) 2021-12-09
EP3843706A1 (en) 2021-07-07
US11000480B2 (en) 2021-05-11
US20220000783A1 (en) 2022-01-06
CA3110020A1 (en) 2020-03-05
DE202019005769U1 (en) 2022-01-13
PH12021550413A1 (en) 2021-09-27
PE20211489A1 (en) 2021-08-11
CR20210158A (en) 2021-05-21
US20200338006A1 (en) 2020-10-29
ECSP21021189A (en) 2021-04-29
US20210401752A1 (en) 2021-12-30
BR112021003788A2 (en) 2021-06-08
CL2021000493A1 (en) 2021-07-23
AU2019329905B2 (en) 2024-02-01
WO2020044314A1 (en) 2020-03-05
KR20210054539A (en) 2021-05-13
CN112912067A (en) 2021-06-04
CO2021003805A2 (en) 2021-04-19
CL2023002539A1 (en) 2024-02-23
EA202190633A1 (en) 2021-07-12
AU2019329905A1 (en) 2021-03-18
TW202034905A (en) 2020-10-01

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