SG11202101821TA - a2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS FOR THE TREATMENT OF SLEEP APNEA - Google Patents

a2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS FOR THE TREATMENT OF SLEEP APNEA

Info

Publication number
SG11202101821TA
SG11202101821TA SG11202101821TA SG11202101821TA SG11202101821TA SG 11202101821T A SG11202101821T A SG 11202101821TA SG 11202101821T A SG11202101821T A SG 11202101821TA SG 11202101821T A SG11202101821T A SG 11202101821TA SG 11202101821T A SG11202101821T A SG 11202101821TA
Authority
SG
Singapore
Prior art keywords
antagonists
alpha
treatment
sleep apnea
adrenoceptor subtype
Prior art date
Application number
SG11202101821TA
Inventor
Martina Delbeck
Michael Hahn
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SG11202101821TA publication Critical patent/SG11202101821TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
SG11202101821TA 2018-09-25 2019-09-19 a2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS FOR THE TREATMENT OF SLEEP APNEA SG11202101821TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18196686 2018-09-25
PCT/EP2019/075102 WO2020064479A1 (en) 2018-09-25 2019-09-19 α2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS FOR THE TREATMENT OF SLEEP APNEA

Publications (1)

Publication Number Publication Date
SG11202101821TA true SG11202101821TA (en) 2021-03-30

Family

ID=63685606

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202101821TA SG11202101821TA (en) 2018-09-25 2019-09-19 a2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS FOR THE TREATMENT OF SLEEP APNEA

Country Status (18)

Country Link
US (1) US20210338662A1 (en)
EP (1) EP3856183A1 (en)
JP (1) JP2022502374A (en)
KR (1) KR20210065948A (en)
CN (1) CN112714647A (en)
AU (1) AU2019350264A1 (en)
BR (1) BR112021003340A2 (en)
CA (1) CA3113700A1 (en)
CL (1) CL2021000707A1 (en)
EA (1) EA202190842A1 (en)
IL (1) IL281645A (en)
JO (1) JOP20210059A1 (en)
MA (1) MA53711A (en)
MX (1) MX2021003428A (en)
SG (1) SG11202101821TA (en)
TW (1) TW202034920A (en)
UA (1) UA128095C2 (en)
WO (1) WO2020064479A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020225185A1 (en) * 2019-05-09 2020-11-12 Bayer Aktiengesellschaft COMBINATION OF AN α2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS WITH A TASK1/3 CHANNEL BLOCKER FOR THE TREATMENT OF SLEEP APNEA
WO2023118098A1 (en) * 2021-12-22 2023-06-29 Bayer Aktiengesellschaft COMBINATION OF AN α2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS WITH A MUSCARINIC RECEPTOR ANTAGONIST FOR THE TREATMENT OF SLEEP APNEA
WO2023131638A1 (en) * 2022-01-07 2023-07-13 Bayer Aktiengesellschaft 2,3-dihydrobenzo [b][1, 4]dioxin-2-ylmethyl)piperazin-1-yl derivates for the treatment of sleep apnea
WO2023249924A1 (en) * 2022-06-21 2023-12-28 Apnimed, Inc. (Delaware) Methods of treating sleep apnea with a combination of a cannabinoid and a carbonic anhydrase inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7103449A (en) * 1971-03-15 1972-09-19
TW201024282A (en) 2008-11-20 2010-07-01 Orion Corp New pharmaceutical compounds
US20180235934A1 (en) * 2015-08-18 2018-08-23 Massachusetts Institute Of Technology Noradrenergic drug treatment of obstructive sleep apnea

Also Published As

Publication number Publication date
CN112714647A (en) 2021-04-27
MA53711A (en) 2021-12-29
MX2021003428A (en) 2021-06-15
BR112021003340A2 (en) 2021-05-11
AU2019350264A1 (en) 2021-03-25
EP3856183A1 (en) 2021-08-04
CL2021000707A1 (en) 2021-08-20
US20210338662A1 (en) 2021-11-04
IL281645A (en) 2021-05-31
EA202190842A1 (en) 2021-07-02
CA3113700A1 (en) 2020-04-02
KR20210065948A (en) 2021-06-04
JOP20210059A1 (en) 2023-01-30
WO2020064479A1 (en) 2020-04-02
TW202034920A (en) 2020-10-01
JP2022502374A (en) 2022-01-11
UA128095C2 (en) 2024-04-03

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