SG11202100931QA - Muscle-targeting complexes and uses thereof - Google Patents

Muscle-targeting complexes and uses thereof

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Publication number
SG11202100931QA
SG11202100931QA SG11202100931QA SG11202100931QA SG11202100931QA SG 11202100931Q A SG11202100931Q A SG 11202100931QA SG 11202100931Q A SG11202100931Q A SG 11202100931QA SG 11202100931Q A SG11202100931Q A SG 11202100931QA SG 11202100931Q A SG11202100931Q A SG 11202100931QA
Authority
SG
Singapore
Prior art keywords
muscle
targeting complexes
targeting
complexes
Prior art date
Application number
SG11202100931QA
Inventor
Romesh Subramanian
Mohammed Qatanani
Timothy Weeden
Jason Rhodes
Original Assignee
Dyne Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyne Therapeutics Inc filed Critical Dyne Therapeutics Inc
Publication of SG11202100931QA publication Critical patent/SG11202100931QA/en

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    • A—HUMAN NECESSITIES
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
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SG11202100931QA 2018-08-02 2019-08-02 Muscle-targeting complexes and uses thereof SG11202100931QA (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201862714010P 2018-08-02 2018-08-02
US201862779173P 2018-12-13 2018-12-13
US201962855781P 2019-05-31 2019-05-31
US201962858925P 2019-06-07 2019-06-07
US201962859694P 2019-06-10 2019-06-10
PCT/US2019/044982 WO2020028857A1 (en) 2018-08-02 2019-08-02 Muscle-targeting complexes and uses thereof

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EP (1) EP3829649A4 (en)
JP (1) JP2021533198A (en)
KR (1) KR20210086602A (en)
CN (1) CN112930197A (en)
AU (1) AU2019315593A1 (en)
CA (1) CA3108335A1 (en)
IL (1) IL280536A (en)
MX (1) MX2021001282A (en)
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WO (1) WO2020028857A1 (en)

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MX2020005860A (en) * 2017-12-06 2020-09-09 Avidity Biosciences Inc Compositions and methods of treating muscle atrophy and myotonic dystrophy.
CA3108282A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
WO2020028840A1 (en) * 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating friedreich's ataxia
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
WO2020028864A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
WO2021195469A1 (en) 2020-03-27 2021-09-30 Avidity Biosciences, Inc. Compositions and methods of treating muscle dystrophy
EP4185383A2 (en) * 2020-07-23 2023-05-31 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
WO2022147209A1 (en) * 2020-12-31 2022-07-07 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
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