SG11202100907TA - Borate of azetidine derivative - Google Patents

Borate of azetidine derivative

Info

Publication number
SG11202100907TA
SG11202100907TA SG11202100907TA SG11202100907TA SG11202100907TA SG 11202100907T A SG11202100907T A SG 11202100907TA SG 11202100907T A SG11202100907T A SG 11202100907TA SG 11202100907T A SG11202100907T A SG 11202100907TA SG 11202100907T A SG11202100907T A SG 11202100907TA
Authority
SG
Singapore
Prior art keywords
borate
azetidine derivative
azetidine
derivative
Prior art date
Application number
SG11202100907TA
Inventor
Jian Xiong
Cheng Xie
Xiongbin Xu
Kevin X Chen
Jian Li
Shuhui Chen
Aiming Zhang
Xiquan Zhang
Xin Tian
Original Assignee
Chia Tai Tianqing Pharmaceutical Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chia Tai Tianqing Pharmaceutical Group Co Ltd filed Critical Chia Tai Tianqing Pharmaceutical Group Co Ltd
Publication of SG11202100907TA publication Critical patent/SG11202100907TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02Boron compounds
    • C07F5/04Esters of boric acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02Boron compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
SG11202100907TA 2018-08-02 2019-08-02 Borate of azetidine derivative SG11202100907TA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201810872672 2018-08-02
CN201810989128 2018-08-28
PCT/CN2019/098990 WO2020025037A1 (en) 2018-08-02 2019-08-02 Borate of azetidine derivative

Publications (1)

Publication Number Publication Date
SG11202100907TA true SG11202100907TA (en) 2021-03-30

Family

ID=69232369

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202100907TA SG11202100907TA (en) 2018-08-02 2019-08-02 Borate of azetidine derivative

Country Status (15)

Country Link
US (1) US11466036B2 (en)
EP (1) EP3831834A4 (en)
JP (1) JP7434273B2 (en)
KR (1) KR20210040109A (en)
CN (2) CN115772188A (en)
AU (1) AU2019315561B2 (en)
BR (1) BR112021001963B1 (en)
CA (1) CA3107925A1 (en)
IL (1) IL280489B1 (en)
MX (1) MX2021001089A (en)
PH (1) PH12021550248A1 (en)
SG (1) SG11202100907TA (en)
TW (1) TWI810344B (en)
WO (1) WO2020025037A1 (en)
ZA (1) ZA202100661B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023198060A1 (en) * 2022-04-12 2023-10-19 正大天晴药业集团股份有限公司 Pharmaceutical combination of proteasome inhibitor and anti-pd-1 antibody

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7468383B2 (en) 2005-02-11 2008-12-23 Cephalon, Inc. Proteasome inhibitors and methods of using the same
MX349769B (en) 2008-06-17 2017-08-11 Millennium Pharm Inc Boronate ester compounds and pharmaceutical compositions thereof.
CN101638414B (en) 2008-07-30 2014-01-08 江苏先声药物研究有限公司 Peptidyl boronic acid, ester compound thereof, preparation method of peptidyl boronic acid and ester compound thereof, and use of peptidyl boronic acid and ester compound thereof
US20140121182A1 (en) 2011-06-22 2014-05-01 Cephalon, Inc. Proteasome inhibitors and processes for their preparation, purification and use
ES2929179T3 (en) 2011-08-30 2022-11-25 Tufts College FAP-activated proteasome inhibitors for the treatment of solid tumors
CN105732683B (en) 2016-03-25 2018-10-16 南京林业大学 The dipeptide boronic acid and its ester type compound, preparation method and its usage of a kind of carboxylic acid and alpha amino acid composition
CN108440583B (en) 2017-01-23 2020-12-04 成都奥璟生物科技有限公司 Boric acid derivative and its medicinal composition
SG11201907945YA (en) * 2017-02-28 2019-09-27 Chia Tai Tianqing Pharmaceutical Group Co Ltd Azetidine derivative

Also Published As

Publication number Publication date
US11466036B2 (en) 2022-10-11
CN115772188A (en) 2023-03-10
EP3831834A1 (en) 2021-06-09
TW202007690A (en) 2020-02-16
BR112021001963A2 (en) 2021-04-27
IL280489B1 (en) 2024-02-01
ZA202100661B (en) 2023-08-30
JP2021531302A (en) 2021-11-18
AU2019315561B2 (en) 2024-01-25
PH12021550248A1 (en) 2021-11-03
WO2020025037A1 (en) 2020-02-06
CN112513052A (en) 2021-03-16
CA3107925A1 (en) 2020-02-06
BR112021001963B1 (en) 2024-02-15
JP7434273B2 (en) 2024-02-20
AU2019315561A1 (en) 2021-02-25
MX2021001089A (en) 2021-05-12
EP3831834A4 (en) 2021-10-27
KR20210040109A (en) 2021-04-12
TWI810344B (en) 2023-08-01
CN112513052B (en) 2022-12-16
US20210163507A1 (en) 2021-06-03
IL280489A (en) 2021-03-25

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