SG11202100561QA - Therapeutic or prophylactic agent for htlv-1-associated myelopathy (ham), and method for treating ham - Google Patents

Therapeutic or prophylactic agent for htlv-1-associated myelopathy (ham), and method for treating ham

Info

Publication number
SG11202100561QA
SG11202100561QA SG11202100561QA SG11202100561QA SG11202100561QA SG 11202100561Q A SG11202100561Q A SG 11202100561QA SG 11202100561Q A SG11202100561Q A SG 11202100561QA SG 11202100561Q A SG11202100561Q A SG 11202100561QA SG 11202100561Q A SG11202100561Q A SG 11202100561QA
Authority
SG
Singapore
Prior art keywords
ham
htlv
therapeutic
prophylactic agent
treating
Prior art date
Application number
SG11202100561QA
Inventor
Kaoru Uchimaru
Makoto Yamagishi
Izumi Ishizaki
Yoshihisa Yamano
Original Assignee
Univ Tokyo
Univ School St Marianna Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tokyo, Univ School St Marianna Medicine filed Critical Univ Tokyo
Publication of SG11202100561QA publication Critical patent/SG11202100561QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74Inducing cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11202100561QA 2018-07-19 2019-07-19 Therapeutic or prophylactic agent for htlv-1-associated myelopathy (ham), and method for treating ham SG11202100561QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018135925 2018-07-19
PCT/JP2019/028431 WO2020017629A1 (en) 2018-07-19 2019-07-19 Agent for treatment or prevention of htlv-1-associated myelopathy (ham), and ham treatment method

Publications (1)

Publication Number Publication Date
SG11202100561QA true SG11202100561QA (en) 2021-02-25

Family

ID=69163691

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202100561QA SG11202100561QA (en) 2018-07-19 2019-07-19 Therapeutic or prophylactic agent for htlv-1-associated myelopathy (ham), and method for treating ham

Country Status (16)

Country Link
US (1) US20210269535A1 (en)
EP (1) EP3824907A4 (en)
JP (2) JP7150286B2 (en)
KR (1) KR20210034055A (en)
CN (4) CN116785439A (en)
AU (1) AU2019306721A1 (en)
BR (1) BR112021000949A2 (en)
CA (1) CA3112511A1 (en)
IL (1) IL280257A (en)
MX (1) MX2021000732A (en)
PE (1) PE20211376A1 (en)
PH (1) PH12021550134A1 (en)
SG (1) SG11202100561QA (en)
TW (2) TW202408577A (en)
WO (1) WO2020017629A1 (en)
ZA (1) ZA202101113B (en)

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1442749A1 (en) * 2003-01-31 2004-08-04 Institut National De La Sante Et De La Recherche Medicale (Inserm) Use of anti-CD100 antibodies for the treatment and the diagnosis of inflammatory disorder affecting the central nervous system
WO2005087268A1 (en) * 2004-03-11 2005-09-22 Bioclues, Inc Axon regeneration promoter
US8962803B2 (en) 2008-02-29 2015-02-24 AbbVie Deutschland GmbH & Co. KG Antibodies against the RGM A protein and uses thereof
CN102131571B (en) 2008-09-02 2014-03-05 东丽电池隔膜株式会社 Microporous polymeric membranes, methods for making such membranes, and use of such membranes as battery separator film
JP5552630B2 (en) 2008-10-24 2014-07-16 学校法人 聖マリアンナ医科大学 Medicament for treating or preventing HTLV-I related myelopathy and method for testing the effect of antibody therapy on patients with HTLV-I related myelopathy
KR20120120193A (en) 2009-12-09 2012-11-01 미쓰비시 타나베 파마 코퍼레이션 T cell activation inhibitor, pharmaceutical composition containing same, and screening method for t cell activation inhibiting substance
DK2665486T3 (en) * 2011-01-18 2020-03-09 Bioniz Llc COMPOSITIONS FOR MODULATING GAMMA-C-CYTOKIN ACTIVITY
JP5963233B2 (en) * 2011-12-07 2016-08-03 学校法人 聖マリアンナ医科大学 Medicament for treating or preventing HTLV-1-related myelopathy and method for confirming therapeutic effect of antibody therapy using said medicament
CA2877848C (en) * 2012-07-06 2021-11-02 St. Marianna University School Of Medicine Therapeutic method and medicament for htlv-1 associated myelopathy (ham)
AU2015314240A1 (en) 2014-09-10 2017-02-09 AbbVie Deutschland GmbH & Co. KG RGMa fragment based diagnostic assay
CN107531791B (en) * 2015-04-28 2021-09-07 田边三菱制药株式会社 RGMa binding proteins and uses thereof
WO2017189963A1 (en) * 2016-04-29 2017-11-02 Voyager Therapeutics, Inc. Compositions for the treatment of disease
US20170349653A1 (en) * 2016-06-01 2017-12-07 Abbvie Inc. Methods for treating spinal cord injury and pain
JP6923215B2 (en) * 2016-08-03 2021-08-18 国立大学法人 鹿児島大学 Anti-HTLV-1 agent, HTLV-1-related myelopathy (HAM / TSP) therapeutic agent

Also Published As

Publication number Publication date
CN112566664B (en) 2023-08-25
ZA202101113B (en) 2022-07-27
TWI825131B (en) 2023-12-11
TW202019482A (en) 2020-06-01
JP2022180487A (en) 2022-12-06
EP3824907A1 (en) 2021-05-26
JP7475011B2 (en) 2024-04-26
KR20210034055A (en) 2021-03-29
WO2020017629A1 (en) 2020-01-23
MX2021000732A (en) 2021-04-28
IL280257A (en) 2021-03-25
CA3112511A1 (en) 2020-01-23
AU2019306721A1 (en) 2021-03-11
TW202408577A (en) 2024-03-01
US20210269535A1 (en) 2021-09-02
BR112021000949A2 (en) 2021-04-27
CN116850291A (en) 2023-10-10
EP3824907A4 (en) 2022-05-04
JPWO2020017629A1 (en) 2021-08-02
CN116942831A (en) 2023-10-27
CN116785439A (en) 2023-09-22
PE20211376A1 (en) 2021-07-27
CN112566664A (en) 2021-03-26
JP7150286B2 (en) 2022-10-11
PH12021550134A1 (en) 2021-09-27

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