SG11202100269VA - Compounds for use in the treatment of fascioliasis - Google Patents

Compounds for use in the treatment of fascioliasis

Info

Publication number
SG11202100269VA
SG11202100269VA SG11202100269VA SG11202100269VA SG11202100269VA SG 11202100269V A SG11202100269V A SG 11202100269VA SG 11202100269V A SG11202100269V A SG 11202100269VA SG 11202100269V A SG11202100269V A SG 11202100269VA SG 11202100269V A SG11202100269V A SG 11202100269VA
Authority
SG
Singapore
Prior art keywords
fascioliasis
compounds
treatment
Prior art date
Application number
SG11202100269VA
Inventor
John Mark Francis Gardner
Andrew Simon Bell
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SG11202100269VA publication Critical patent/SG11202100269VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • A61P33/12Schistosomicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11202100269VA 2018-07-17 2019-07-16 Compounds for use in the treatment of fascioliasis SG11202100269VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1811695.4A GB201811695D0 (en) 2018-07-17 2018-07-17 Compounds for use in the treatment of fascioliasis
PCT/EP2019/069134 WO2020016235A1 (en) 2018-07-17 2019-07-16 Compounds for use in the treatment of fascioliasis

Publications (1)

Publication Number Publication Date
SG11202100269VA true SG11202100269VA (en) 2021-02-25

Family

ID=63273364

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202100269VA SG11202100269VA (en) 2018-07-17 2019-07-16 Compounds for use in the treatment of fascioliasis

Country Status (11)

Country Link
US (1) US20210230169A1 (en)
EP (1) EP3823728A1 (en)
JP (1) JP7449270B2 (en)
KR (1) KR20210032407A (en)
CN (1) CN112512636B (en)
AU (1) AU2019304487B2 (en)
BR (1) BR112021000576A2 (en)
GB (1) GB201811695D0 (en)
PH (1) PH12021550093A1 (en)
SG (1) SG11202100269VA (en)
WO (1) WO2020016235A1 (en)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH590862A5 (en) * 1974-02-26 1977-08-31 Ciba Geigy Ag Isothiocyanato-substd. (2)-phenyl-imidazo (1,2-a)-pyridines prodn. - from corresp. amine and thiocarbonic acid derivs., useful as anthelmintics
WO2007096764A2 (en) 2006-02-27 2007-08-30 Glenmark Pharmaceuticals S.A. Bicyclic heteroaryl derivatives as cannabinoid receptor modulators
US7875613B2 (en) * 2006-10-30 2011-01-25 Hybrigenics Sa Tetracyclic inhibitors of cysteine proteases, the pharmaceutical compositions thereof and their therapeutic applications
US8895745B2 (en) * 2006-12-22 2014-11-25 Astex Therapeutics Limited Bicyclic heterocyclic compounds as FGFR inhibitors
WO2009133127A1 (en) * 2008-04-30 2009-11-05 Merck Serono S.A. Fused bicyclic compounds and use thereof as pi3k inhibitors
US8975265B2 (en) * 2010-07-12 2015-03-10 Bayer Intellectual Property Gmbh Substituted imidazo[1,2-a]pyrimidines and —pyridines
JP5822944B2 (en) 2010-12-17 2015-11-25 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH Disubstituted imidazopyrazines for use as MPS-1 and TKK inhibitors in the treatment of hyperproliferative disorders
BR112014026184B1 (en) * 2012-04-20 2019-04-24 Merial, Inc. PARASITICIDIC COMPOSITIONS UNDERSTANDING BENZIMIDAZOLE DERIVATIVES, METHODS AND THEIR USES
JP2016500073A (en) 2012-11-19 2016-01-07 ノバルティス アーゲー Compounds and compositions for the treatment of parasitic diseases
CN105164124B (en) 2012-11-19 2017-03-15 诺华股份有限公司 For treating compound and the compositionss of parasitic disease
AU2013372386B2 (en) * 2013-01-10 2018-04-19 Merck Patent Gmbh Piperidinylcarbazole as antimalarial
CA2953843C (en) * 2014-07-04 2023-03-14 Merck Patent Gmbh Azepanyl-derivatives and pharmaceutical compositions comprising the same with antiparasitic activity
WO2016097759A1 (en) 2014-12-19 2016-06-23 Aberystwyth University Anthelmintic compounds
EP3270694A4 (en) 2015-02-17 2018-09-05 Neupharma, Inc. Certain chemical entities, compositions, and methods
CR20190101A (en) * 2016-09-02 2019-07-04 Ironwood Pharmaceuticals Inc Fused bicyclic sgc stimulators
GB201700692D0 (en) 2017-01-16 2017-03-01 Salvensis Novel compounds and their use in the treatment of schistosomiasis

Also Published As

Publication number Publication date
GB201811695D0 (en) 2018-08-29
US20210230169A1 (en) 2021-07-29
BR112021000576A2 (en) 2021-04-06
JP7449270B2 (en) 2024-03-13
KR20210032407A (en) 2021-03-24
EP3823728A1 (en) 2021-05-26
CN112512636A (en) 2021-03-16
AU2019304487B2 (en) 2024-05-02
AU2019304487A1 (en) 2021-03-11
JP2021530509A (en) 2021-11-11
PH12021550093A1 (en) 2021-09-27
WO2020016235A1 (en) 2020-01-23
CN112512636B (en) 2024-06-18

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