SG11202013220SA - Anhydrous sodium thiosulfate and formulations thereof - Google Patents

Anhydrous sodium thiosulfate and formulations thereof

Info

Publication number
SG11202013220SA
SG11202013220SA SG11202013220SA SG11202013220SA SG11202013220SA SG 11202013220S A SG11202013220S A SG 11202013220SA SG 11202013220S A SG11202013220S A SG 11202013220SA SG 11202013220S A SG11202013220S A SG 11202013220SA SG 11202013220S A SG11202013220S A SG 11202013220SA
Authority
SG
Singapore
Prior art keywords
formulations
anhydrous sodium
sodium thiosulfate
thiosulfate
anhydrous
Prior art date
Application number
SG11202013220SA
Inventor
Thomas Lovelace
Joseph Moore
Christopher Lee
Daniel Kirschner
Original Assignee
Fennec Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=69060534&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11202013220S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fennec Pharmaceuticals Inc filed Critical Fennec Pharmaceuticals Inc
Publication of SG11202013220SA publication Critical patent/SG11202013220SA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B17/00Sulfur; Compounds thereof
    • C01B17/64Thiosulfates; Dithionites; Polythionates
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00Crystal-structural characteristics
    • C01P2002/70Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
    • C01P2002/72Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by d-values or two theta-values, e.g. as X-ray diagram

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
SG11202013220SA 2018-07-03 2019-07-01 Anhydrous sodium thiosulfate and formulations thereof SG11202013220SA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862693503P 2018-07-03 2018-07-03
US201862693502P 2018-07-03 2018-07-03
PCT/US2019/040051 WO2020009953A1 (en) 2018-07-03 2019-07-01 Anhydrous sodium thiosulfate and formulations thereof

Publications (1)

Publication Number Publication Date
SG11202013220SA true SG11202013220SA (en) 2021-01-28

Family

ID=69060534

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11202013199UA SG11202013199UA (en) 2018-07-03 2019-07-01 Formulations of anhydrous sodium thiosulfate
SG11202013220SA SG11202013220SA (en) 2018-07-03 2019-07-01 Anhydrous sodium thiosulfate and formulations thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11202013199UA SG11202013199UA (en) 2018-07-03 2019-07-01 Formulations of anhydrous sodium thiosulfate

Country Status (13)

Country Link
US (14) US20200023003A1 (en)
EP (2) EP3818010A4 (en)
JP (2) JP2021530420A (en)
KR (2) KR20210027409A (en)
CN (2) CN112805238A (en)
AU (2) AU2019299217A1 (en)
BR (2) BR112021000021A2 (en)
CA (2) CA3103986A1 (en)
IL (2) IL279857A (en)
MA (2) MA53101A (en)
MX (2) MX2020013734A (en)
SG (2) SG11202013199UA (en)
WO (2) WO2020009954A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7492917B2 (en) 2018-02-09 2024-05-30 デシベル セラピューティクス インコーポレイテッド Hypertonic pharmaceutical compositions containing antiplatinum chemoprotectants - Patent Application 20070223333
BR112021000021A2 (en) 2018-07-03 2021-03-30 Fennec Pharmaceuticals, Inc. ANhydrous SODIUM THYOSULFATE AND FORMULATIONS OF THE SAME
US10813947B1 (en) 2019-05-31 2020-10-27 Decibel Therapeutics, Inc. Methods of otoprotection against platinum-based antineoplastic agents
CN114848597A (en) * 2022-07-11 2022-08-05 北京中科利华医药研究院有限公司 Sodium thiosulfate injection packaged by double-chamber bag and application
CN116062708A (en) * 2022-12-02 2023-05-05 东南大学 Synthetic method of sodium thiosulfate

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB191512599A (en) * 1915-09-02 1916-09-04 Thomas William Staine Hutchins Improvements in the Process for the Manufacture of Sodium Thiosulphate.
US2635980A (en) * 1950-02-11 1953-04-21 Wm S Merrell Co Stabilized sulfa drug
GB713559A (en) * 1951-12-14 1954-08-11 Kodak Ltd Improvements in the manufacture of the thiosulphates and seleno-sulphates of the alkali metals, calcium and ammonium
US2763531A (en) * 1952-11-29 1956-09-18 Eastman Kodak Co Manufacture of sodium thiosulphate from sodium sulfite and sulfur in presence of cationic surface active organic bromides
DE2851037C2 (en) * 1978-11-25 1980-10-02 Dr. Franz Koehler Chemie, 6146 Alsbach Process for the stabilization of sodium thiosulphate solutions intended for medical purposes
US4778519A (en) 1987-02-24 1988-10-18 Batric Pesic Recovery of precious metals from a thiourea leach
AU2001253919B2 (en) 2000-04-26 2006-12-14 Government Of The United States, D/B/A Department Of Veterans Affairs Administration of a thiol-based chemoprotectant compound
JP5000848B2 (en) * 2002-05-21 2012-08-15 第一三共株式会社 Ghrelin-containing pharmaceutical composition
BRPI0413197A (en) * 2003-08-01 2006-10-03 Amgen Inc eta wercept crystal; method for making an etanercept crystal; composition; use of an etanercept crystal
US20070059382A1 (en) 2005-09-09 2007-03-15 Board Of Regents, Univ. And Comm. College System Of Nevada... Medical treatment of breast cancer with boric acid materials
US20100016450A1 (en) * 2008-07-21 2010-01-21 Otonomy, Inc. Controlled release delivery devices for the treatment of otic disorders
EP2321351B1 (en) * 2008-08-18 2017-11-01 Pfizer Inc. Antibodies to ccr2
DK2451435T4 (en) * 2009-07-08 2022-02-28 Hope Medical Entpr Inc D B A Hope Pharmaceuticals SODIUM THIOSULPHATE CONTAINING PHARMACEUTICAL COMPOSITIONS
WO2013096901A1 (en) * 2011-12-23 2013-06-27 Mersana Therapeutics, Inc. Pharmaceutical formulations for fumagillin derivative-phf conjugates
JP2015516407A (en) * 2012-05-10 2015-06-11 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル Sodium thiosulfate for the treatment of ectopic calcification
JP5478680B2 (en) 2012-08-23 2014-04-23 小林製薬株式会社 Stabilizer for composition containing water-soluble polymer thickener
NL1040254C2 (en) 2013-05-17 2014-11-24 Ablynx Nv Stable formulations of immunoglobulin single variable domains and uses thereof.
BR112016005340A2 (en) 2013-09-16 2017-09-12 Basf Enzymes Llc controlled breakdown enzyme formulations
CA2927393A1 (en) 2013-10-18 2015-04-23 Moderna Therapeutics, Inc. Compositions and methods for tolerizing cellular systems
WO2015085318A2 (en) 2013-12-06 2015-06-11 Moderna Therapeutics, Inc. Targeted adaptive vaccines
PT3134131T (en) 2014-04-23 2022-03-24 Modernatx Inc Nucleic acid vaccines
CN103922292A (en) * 2014-04-29 2014-07-16 辽宁石化职业技术学院 Method for preparing sodium thiosulfate
KR20180080189A (en) * 2015-09-01 2018-07-11 퍼스트 웨이브 바이오, 인코포레이티드 And compositions for treating diseases associated with abnormal inflammatory response
BR112018006471B1 (en) * 2015-10-01 2024-02-27 Senomyx, Inc COMPOUND, COMPOSITION, METHOD OF MODULATING THE MELASTIN MEMBER OF TRANSIENT RECEPTOR POTENTIAL CHANNEL 8 (TRPM8), METHOD OF MODULATING THE FEELING OF REFRESHMENT OF A COMPOSITION, AND METHOD OF INDUCING A FEELING OF REFRESHMENT IN A HUMAN OR ANIMAL
WO2017075335A1 (en) 2015-10-28 2017-05-04 Voyager Therapeutics, Inc. Regulatable expression using adeno-associated virus (aav)
ES2751082T3 (en) 2015-10-30 2020-03-30 Pipeline Therapeutics Inc Dibenzo azepine compounds and their use in the treatment of ear diseases and disorders
US20170087199A1 (en) 2016-02-10 2017-03-30 Senomyx, Inc. Compositions for delivering a cooling sensation
CA3029281A1 (en) * 2016-06-29 2018-01-04 Otonomy, Inc. Triglyceride otic formulations and uses thereof
US20160376263A1 (en) 2016-07-26 2016-12-29 Senomyx, Inc. Bitter taste modifiers including substituted 1-benzyl-3-(1-(isoxazol-4-ylmethyl)-1h-pyrazol-4-yl)imidazolidine-2,4-diones and compositions thereof
CN107963614A (en) * 2016-10-20 2018-04-27 王亚玲 A kind of quick method for preparing high-purity thiosulfuric acid sodium crystal
CN106379867A (en) * 2016-10-21 2017-02-08 金川集团股份有限公司 Method for producing sodium thiosulfate pentahydrate
JP7416622B2 (en) 2017-03-08 2024-01-17 ホープ メディカル エンタープライズ インコーポレイテッド ディー.ビー.エー. ホープ ファーマシューティカルズ Use of sodium thiosulfate during dialysis
MX2019014748A (en) 2017-06-08 2020-08-03 Eye Therapies Llc Low-dose brimonidine combinations and uses thereof.
US10596190B2 (en) 2017-11-29 2020-03-24 Oregon Health & Science University Method for reducing ototoxicity in pediatric patients receiving platinum-based chemotherapy
WO2019210107A1 (en) * 2018-04-25 2019-10-31 Otonomy, Inc. Otic formulations for drug-induced ototoxicity
BR112021000021A2 (en) 2018-07-03 2021-03-30 Fennec Pharmaceuticals, Inc. ANhydrous SODIUM THYOSULFATE AND FORMULATIONS OF THE SAME
US10813947B1 (en) * 2019-05-31 2020-10-27 Decibel Therapeutics, Inc. Methods of otoprotection against platinum-based antineoplastic agents

Also Published As

Publication number Publication date
US20230158145A1 (en) 2023-05-25
US11964018B2 (en) 2024-04-23
EP3817751A1 (en) 2021-05-12
JP2021530462A (en) 2021-11-11
US20200009255A1 (en) 2020-01-09
SG11202013199UA (en) 2021-01-28
WO2020009954A1 (en) 2020-01-09
WO2020009953A1 (en) 2020-01-09
US20240165237A1 (en) 2024-05-23
US11992530B2 (en) 2024-05-28
US10792363B2 (en) 2020-10-06
US20240042036A1 (en) 2024-02-08
EP3818010A1 (en) 2021-05-12
US20210015923A1 (en) 2021-01-21
US11617793B2 (en) 2023-04-04
AU2019299216A1 (en) 2021-01-07
KR20210027409A (en) 2021-03-10
US20230094842A1 (en) 2023-03-30
MX2020013734A (en) 2021-05-27
US11291728B2 (en) 2022-04-05
IL279856A (en) 2021-03-01
EP3818010A4 (en) 2022-08-17
JP2021530420A (en) 2021-11-11
US20200023003A1 (en) 2020-01-23
BR112021000021A2 (en) 2021-03-30
CA3103986A1 (en) 2020-01-09
CN112805238A (en) 2021-05-14
US20220378915A1 (en) 2022-12-01
IL279857A (en) 2021-03-01
BR112021000022A2 (en) 2021-03-30
US20220323586A1 (en) 2022-10-13
MX2020013733A (en) 2021-05-27
US20230201349A1 (en) 2023-06-29
MA53102A (en) 2022-05-11
CN112805014A (en) 2021-05-14
US20230201351A1 (en) 2023-06-29
KR20210027410A (en) 2021-03-10
MA53101A (en) 2021-05-12
US11510984B2 (en) 2022-11-29
US20220160875A1 (en) 2022-05-26
US11998604B2 (en) 2024-06-04
AU2019299217A1 (en) 2021-01-14
EP3817751A4 (en) 2022-05-11
US20230201350A1 (en) 2023-06-29
US20230094886A1 (en) 2023-03-30
CA3103982A1 (en) 2020-01-09

Similar Documents

Publication Publication Date Title
IL279857A (en) Anhydrous sodium thiosulfate and formulations thereof
GB2559774B (en) Oral cannabinoid formulations
IL280135A (en) Elagolix sodium compositions and processes
PL3818050T3 (en) Substituted thiophenecarboxamides and analogues as antibacterials agents
IL295119B1 (en) Intradialytic use of sodium thiosulfate
IL261777A (en) Palatable compositions including sodium phenylbutyrate and uses thereof
ZA202005143B (en) Oral formulations and uses thereof
GB201809976D0 (en) Novel formulations
IL277791A (en) Hsp90-targeting conjugates and formulations thereof
ZA202000490B (en) Novel secnidazole soft gelatin capsule formulations and uses thereof
SG11202007976WA (en) Formulations containing mucin-affecting proteases
IL283450A (en) Capsule formulations
SG11202011823SA (en) Activator-nucleator formulations
GB201819028D0 (en) Butanol-based formulations
HUE054988T2 (en) Oral thyroid therapeutic agent
GB201804545D0 (en) Formulations
GB201803201D0 (en) Formulations