SG11202012278XA - Cell culture system and cell culture method - Google Patents

Cell culture system and cell culture method

Info

Publication number
SG11202012278XA
SG11202012278XA SG11202012278XA SG11202012278XA SG11202012278XA SG 11202012278X A SG11202012278X A SG 11202012278XA SG 11202012278X A SG11202012278X A SG 11202012278XA SG 11202012278X A SG11202012278X A SG 11202012278XA SG 11202012278X A SG11202012278X A SG 11202012278XA
Authority
SG
Singapore
Prior art keywords
cell culture
culture system
culture method
cell
culture
Prior art date
Application number
SG11202012278XA
Inventor
Ryosuke Ikeda
Yoshiyuki Iso
Koichi Kamekura
Takato Mizunuma
Original Assignee
Ihi Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ihi Corp filed Critical Ihi Corp
Publication of SG11202012278XA publication Critical patent/SG11202012278XA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12—Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
SG11202012278XA 2018-06-13 2019-06-13 Cell culture system and cell culture method SG11202012278XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018112890A JP7087704B2 (en) 2018-06-13 2018-06-13 Cell culture system and cell culture method
PCT/JP2019/023482 WO2019240222A1 (en) 2018-06-13 2019-06-13 Cell culturing system and cell culturing method

Publications (1)

Publication Number Publication Date
SG11202012278XA true SG11202012278XA (en) 2021-01-28

Family

ID=68841959

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202012278XA SG11202012278XA (en) 2018-06-13 2019-06-13 Cell culture system and cell culture method

Country Status (7)

Country Link
US (1) US20210087512A1 (en)
EP (1) EP3808833A4 (en)
JP (1) JP7087704B2 (en)
KR (1) KR102567418B1 (en)
CN (1) CN112262209A (en)
SG (1) SG11202012278XA (en)
WO (1) WO2019240222A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3907276A4 (en) * 2020-03-11 2022-03-30 Showa Denko Materials Co., Ltd. Cell recovery device, cell recovery method, cell separation system, and cell separation method
CN111592985B (en) * 2020-04-28 2024-02-06 郑州伊美诺生物技术有限公司 Continuous culture device and method for hybridoma cells
JP2023003462A (en) 2021-06-24 2023-01-17 横河電機株式会社 Liquid processing device for use in cell culture process
JP2023003954A (en) * 2021-06-25 2023-01-17 東洋製罐グループホールディングス株式会社 Cell culture method, cell culture kit, and cell culture system

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4146476B2 (en) * 2006-05-26 2008-09-10 シャープ株式会社 Biological reactor
US8931644B2 (en) * 2006-11-30 2015-01-13 Palo Alto Research Center Incorporated Method and apparatus for splitting fluid flow in a membraneless particle separation system
JP4910909B2 (en) * 2007-06-26 2012-04-04 株式会社日立プラントテクノロジー Microreactor system
FR2931080B1 (en) * 2008-05-13 2010-07-30 Commissariat Energie Atomique METHOD AND DEVICE FOR EXTRACTING A LIQUID PHASE FROM A SUSPENSION
JP5881135B2 (en) * 2008-09-30 2016-03-09 東レ株式会社 Chemical production method and continuous culture apparatus
US8208138B2 (en) * 2009-09-24 2012-06-26 University Of Cincinnati Spiral microchannel particle separators, straight microchannel particle separators, and continuous particle separator and detector systems
CA2861270C (en) 2012-01-18 2021-08-03 Bayer Healthcare Llc Perfusion bioreactor systems comprising a cell aggregate trap and methods of operating the same
JP6265508B2 (en) * 2012-09-21 2018-01-24 マサチューセッツ インスティテュート オブ テクノロジー Microfluidic device and use thereof
JP6311014B2 (en) 2013-06-14 2018-04-11 パロ・アルト・リサーチ・センター・インコーポレーテッドＰａｌｏ Ａｌｔｏ Ｒｅｓｅａｒｃｈ Ｃｅｎｔｅｒ Ｉｎｃｏｒｐｏｒａｔｅｄ Hydrodynamic separation using high aspect ratio channels
US20160312168A1 (en) 2013-12-30 2016-10-27 Ge Healthcare Bio-Sciences Corp. Apparatus for cell cultivation
EP3194560A4 (en) * 2014-09-17 2018-06-06 Massachusetts Institute of Technology Microfluidic system and method for perfusion bioreactor cell retention
CN113663749B (en) * 2016-07-21 2023-06-20 新加坡科技研究局 Apparatus for outer wall focusing for high volume fraction particle microfiltration and method of making same
WO2018067915A1 (en) * 2016-10-07 2018-04-12 Massachusetts Institute Of Technology Particle isolation/enrichment using continuous closed-loop micro-fluidics

Also Published As

Publication number Publication date
EP3808833A1 (en) 2021-04-21
WO2019240222A1 (en) 2019-12-19
JP2019213497A (en) 2019-12-19
KR102567418B1 (en) 2023-08-14
EP3808833A4 (en) 2021-07-28
US20210087512A1 (en) 2021-03-25
KR20210021021A (en) 2021-02-24
JP7087704B2 (en) 2022-06-21
CN112262209A (en) 2021-01-22

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