SG11202011648UA - Il-11ra antibodies - Google Patents

Il-11ra antibodies

Info

Publication number
SG11202011648UA
SG11202011648UA SG11202011648UA SG11202011648UA SG11202011648UA SG 11202011648U A SG11202011648U A SG 11202011648UA SG 11202011648U A SG11202011648U A SG 11202011648UA SG 11202011648U A SG11202011648U A SG 11202011648UA SG 11202011648U A SG11202011648U A SG 11202011648UA
Authority
SG
Singapore
Prior art keywords
antibodies
Prior art date
Application number
SG11202011648UA
Inventor
Stuart Alexander Cook
Sebastian Schaefer
Original Assignee
Singapore Health Serv Pte Ltd
Nat Univ Singapore
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Singapore Health Serv Pte Ltd, Nat Univ Singapore, Boehringer Ingelheim Int filed Critical Singapore Health Serv Pte Ltd
Publication of SG11202011648UA publication Critical patent/SG11202011648UA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/6857Antibody fragments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
SG11202011648UA 2018-06-13 2019-06-13 Il-11ra antibodies SG11202011648UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1809700.6A GB201809700D0 (en) 2018-06-13 2018-06-13 IL-11 antibodies
PCT/EP2019/065600 WO2019238884A1 (en) 2018-06-13 2019-06-13 Il-11ra antibodies

Publications (1)

Publication Number Publication Date
SG11202011648UA true SG11202011648UA (en) 2020-12-30

Family

ID=63042296

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202011648UA SG11202011648UA (en) 2018-06-13 2019-06-13 Il-11ra antibodies

Country Status (24)

Country Link
US (1) US11084878B2 (en)
EP (1) EP3806959A1 (en)
JP (1) JP7437325B2 (en)
KR (1) KR20210031645A (en)
CN (1) CN113226471A (en)
AU (1) AU2019286797A1 (en)
BR (1) BR112020025502A2 (en)
CA (1) CA3101401A1 (en)
CL (1) CL2020003218A1 (en)
CO (1) CO2020015376A2 (en)
CR (1) CR20210010A (en)
DO (1) DOP2020000236A (en)
EA (1) EA202092605A1 (en)
EC (1) ECSP21001499A (en)
GB (1) GB201809700D0 (en)
IL (1) IL279352A (en)
JO (1) JOP20200300A1 (en)
MA (1) MA52885A (en)
MX (1) MX2020013468A (en)
PE (1) PE20211500A1 (en)
PH (1) PH12020552229A1 (en)
SG (1) SG11202011648UA (en)
TW (1) TW202016140A (en)
WO (1) WO2019238884A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201522186D0 (en) 2015-12-16 2016-01-27 Singapore Health Services Pte Ltd And Nat University Of Singapore The Treatment of fibrosis
GB201621439D0 (en) 2016-12-16 2017-02-01 Singapore Health Services Pte Ltd And Nat Univ Of Singapore IL-11Ra Antibodies
KR20190096390A (en) 2016-12-16 2019-08-19 싱가포르 헬스 서비시즈 피티이 엘티디 IL-11 antibody
AU2020211695A1 (en) 2019-01-21 2021-09-02 National University Of Singapore Treatment of hepatotoxicity
GB201902419D0 (en) 2019-02-22 2019-04-10 Singapore Health Serv Pte Ltd Treatment of kidney injury
TW202108606A (en) 2019-05-03 2021-03-01 新加坡商新加坡保健服務私人有限公司 Treatment and prevention of metabolic diseases
GB202009292D0 (en) 2020-06-18 2020-08-05 Singapore Health Serv Pte Ltd Treatment and prevention of disease caused by type IV collagen dysfunction
EP3939999A1 (en) * 2020-07-14 2022-01-19 Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Interleukin 11 receptor alpha subunit (il11ra) neutralizing antibodies and uses thereof
GB202017244D0 (en) 2020-10-30 2020-12-16 Nat Univ Singapore Methods to extend health-span and treat age-related diseases
CN117157317A (en) 2021-02-26 2023-12-01 拜耳公司 Inhibitors of IL-11 or IL-11Ra for the treatment of abnormal uterine bleeding
IL309804A (en) * 2021-07-02 2024-02-01 Laekna Therapeutics Shanghai Co Ltd Depletion of activated hepatic stellate cells (hscs) and uses thereof
WO2023006765A1 (en) 2021-07-26 2023-02-02 Boehringer Ingelheim International Gmbh Treatment and prevention of alcoholic liver disease
CN113735975B (en) * 2021-09-07 2022-08-12 广东东阳光药业有限公司 anti-IL-11R antibody and application thereof
WO2023111196A1 (en) 2021-12-16 2023-06-22 Singapore Health Services Pte. Ltd. Treatment and prevention of glomerular disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1598364A1 (en) * 2004-05-21 2005-11-23 AGIRx Limited Chimerical soluble hyper IL-11 receptor and use thereof
WO2014121325A1 (en) * 2013-02-07 2014-08-14 Csl Limited Il-11r binding proteins and uses thereof
US10308719B2 (en) * 2015-01-26 2019-06-04 The University Of Chicago IL13Rα2 binding agents and use thereof in cancer treatment
GB201522186D0 (en) 2015-12-16 2016-01-27 Singapore Health Services Pte Ltd And Nat University Of Singapore The Treatment of fibrosis
GB201621439D0 (en) * 2016-12-16 2017-02-01 Singapore Health Services Pte Ltd And Nat Univ Of Singapore IL-11Ra Antibodies

Also Published As

Publication number Publication date
CN113226471A (en) 2021-08-06
EA202092605A1 (en) 2021-06-01
US20190389957A1 (en) 2019-12-26
AU2019286797A1 (en) 2021-01-28
JP7437325B2 (en) 2024-02-22
BR112020025502A2 (en) 2021-03-16
MX2020013468A (en) 2021-04-13
KR20210031645A (en) 2021-03-22
CL2020003218A1 (en) 2021-07-30
ECSP21001499A (en) 2021-03-31
MA52885A (en) 2021-04-21
GB201809700D0 (en) 2018-08-01
WO2019238884A1 (en) 2019-12-19
JOP20200300A1 (en) 2020-11-22
DOP2020000236A (en) 2021-10-31
PH12020552229A1 (en) 2021-06-28
IL279352A (en) 2021-01-31
TW202016140A (en) 2020-05-01
US11084878B2 (en) 2021-08-10
EP3806959A1 (en) 2021-04-21
CA3101401A1 (en) 2019-12-19
JP2021527086A (en) 2021-10-11
CO2020015376A2 (en) 2021-04-19
PE20211500A1 (en) 2021-08-11
US20200377605A9 (en) 2020-12-03
CR20210010A (en) 2021-06-01

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