SG11202011638WA - Fused-cyclic pyrazolone formamide compound and preparation method therefor, pharmaceutical composition and use thereof - Google Patents
Fused-cyclic pyrazolone formamide compound and preparation method therefor, pharmaceutical composition and use thereofInfo
- Publication number
- SG11202011638WA SG11202011638WA SG11202011638WA SG11202011638WA SG11202011638WA SG 11202011638W A SG11202011638W A SG 11202011638WA SG 11202011638W A SG11202011638W A SG 11202011638WA SG 11202011638W A SG11202011638W A SG 11202011638WA SG 11202011638W A SG11202011638W A SG 11202011638WA
- Authority
- SG
- Singapore
- Prior art keywords
- fused
- preparation
- pharmaceutical composition
- method therefor
- formamide compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810491115.3A CN110511218A (en) | 2018-05-21 | 2018-05-21 | A kind of and ring pyrazolone Carbox amide and preparation method thereof, pharmaceutical composition and purposes |
| PCT/CN2019/087867 WO2019223704A1 (en) | 2018-05-21 | 2019-05-21 | Fused-cyclic pyrazolone formamide compound and preparation method therefor, pharmaceutical composition and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202011638WA true SG11202011638WA (en) | 2020-12-30 |
Family
ID=68615979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202011638WA SG11202011638WA (en) | 2018-05-21 | 2019-05-21 | Fused-cyclic pyrazolone formamide compound and preparation method therefor, pharmaceutical composition and use thereof |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20210221807A1 (en) |
| EP (1) | EP3798218A4 (en) |
| JP (1) | JP7339282B2 (en) |
| KR (1) | KR102658011B1 (en) |
| CN (2) | CN110511218A (en) |
| AU (1) | AU2019273337B2 (en) |
| BR (1) | BR112020023870A2 (en) |
| CA (1) | CA3101223A1 (en) |
| EA (1) | EA202092766A1 (en) |
| SG (1) | SG11202011638WA (en) |
| WO (1) | WO2019223704A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190043437A (en) | 2017-10-18 | 2019-04-26 | 씨제이헬스케어 주식회사 | Heterocylic compound as a protein kinase inhibitor |
| CN113683629B (en) * | 2020-05-18 | 2023-07-04 | 北京范恩柯尔生物科技有限公司 | Substituted heteroaryl compounds, compositions and uses thereof |
| WO2024039842A2 (en) * | 2022-08-19 | 2024-02-22 | National Health Research Institutes | Inhibitors of tam receptors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO2787B1 (en) | 2005-04-27 | 2014-03-15 | امجين إنك, | Substituted Amid derivatives & methods of use |
| CA2738583A1 (en) * | 2008-10-01 | 2010-04-08 | Ludwig Institute For Cancer Research | Methods for the treatment of cancer |
| KR100961410B1 (en) * | 2008-10-14 | 2010-06-09 | (주)네오팜 | Heterocyclic compounds as protein kinases inhibitors |
| CN102086211B (en) | 2009-12-08 | 2013-09-11 | 广东东阳光药业有限公司 | Aromatic heterocyclic compounds serving as protein kinase inhibitor |
| JP6051434B2 (en) * | 2011-11-14 | 2016-12-27 | イグニタ、インク． | Uracil derivatives as AXL and c-MET kinase inhibitors |
| CN104974162B (en) | 2014-04-09 | 2018-09-14 | 广东东阳光药业有限公司 | Bicyclic pyrazolone compounds and its application method and purposes |
| WO2016104617A1 (en) | 2014-12-25 | 2016-06-30 | 小野薬品工業株式会社 | Quinoline derivative |
-
2018
- 2018-05-21 CN CN201810491115.3A patent/CN110511218A/en active Pending
-
2019
- 2019-05-21 BR BR112020023870-8A patent/BR112020023870A2/en unknown
- 2019-05-21 KR KR1020207036703A patent/KR102658011B1/en active IP Right Grant
- 2019-05-21 SG SG11202011638WA patent/SG11202011638WA/en unknown
- 2019-05-21 AU AU2019273337A patent/AU2019273337B2/en active Active
- 2019-05-21 EA EA202092766A patent/EA202092766A1/en unknown
- 2019-05-21 US US17/057,199 patent/US20210221807A1/en active Pending
- 2019-05-21 WO PCT/CN2019/087867 patent/WO2019223704A1/en unknown
- 2019-05-21 CA CA3101223A patent/CA3101223A1/en active Pending
- 2019-05-21 CN CN201980034774.7A patent/CN112236430B/en active Active
- 2019-05-21 JP JP2020565414A patent/JP7339282B2/en active Active
- 2019-05-21 EP EP19806732.4A patent/EP3798218A4/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN112236430B (en) | 2023-02-17 |
| EP3798218A1 (en) | 2021-03-31 |
| KR20210011988A (en) | 2021-02-02 |
| AU2019273337A1 (en) | 2021-01-21 |
| KR102658011B1 (en) | 2024-04-17 |
| CN112236430A (en) | 2021-01-15 |
| US20210221807A1 (en) | 2021-07-22 |
| JP7339282B2 (en) | 2023-09-05 |
| AU2019273337B2 (en) | 2022-02-17 |
| WO2019223704A1 (en) | 2019-11-28 |
| EA202092766A1 (en) | 2021-07-08 |
| CN110511218A (en) | 2019-11-29 |
| EP3798218A4 (en) | 2022-03-02 |
| BR112020023870A2 (en) | 2021-02-09 |
| JP2021524471A (en) | 2021-09-13 |
| CA3101223A1 (en) | 2019-11-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG11202105850YA (en) | Diphenyl-like compound, intermediate thereof, preparation method therefor, pharmaceutical composition thereof and uses thereof | |
| ZA202001447B (en) | M-diamide compound and preparation method therefor and use thereof | |
| IL288104A (en) | Heterocyclic compounds, preparation methods and uses thereof | |
| EP3539963A4 (en) | Nitrogen-containing heterocyclic compound, preparation method, intermediate, pharmaceutical composition and use | |
| SG11202106706TA (en) | Heterocyclic compound intermediate, preparation method therefor and application thereof | |
| EP3835296A4 (en) | Ketoamide compound and preparation method, pharmaceutical composition, and use thereof | |
| PL3453707T3 (en) | Benzazepine derivative, preparation method, pharmaceutical composition and use thereof | |
| HUE049952T2 (en) | Pyrazolone compound or salt thereof, preparation method therefor, herbicide composition and use thereof | |
| EP3424928A4 (en) | Nitrogenous heterocyclic compound, preparation method, intermediate, composition and use | |
| PT3580208T (en) | Novel heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same | |
| IL272446A (en) | Substituted penta- fused hexa-heterocyclic compounds, preparation method therefor, drug combination and use thereof | |
| EP3556761A4 (en) | Pyrrolo-aromatic heterocyclic compound, preparation method therefor, and medical use thereof | |
| EP3715342A4 (en) | Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof | |
| SG11202011638WA (en) | Fused-cyclic pyrazolone formamide compound and preparation method therefor, pharmaceutical composition and use thereof | |
| IL285378A (en) | Heterocyclic compound, pharmaceutical composition comprising same, preparation method therefor, and use thereof | |
| EP3789384A4 (en) | Formamide compound, preparation method therefor and application thereof | |
| GB201904104D0 (en) | Composition, method and use | |
| IL282817A (en) | Novel compound, preparation method and application thereof | |
| EP3741759A4 (en) | Heterocyclic compound, preparation method and use thereof in medicine | |
| SG11202008531RA (en) | Oxazino-quinazoline and Oxazino-quinoline Type Compound, Preparation Method and Uses Thereof | |
| PL3750893T3 (en) | Dioxazoline compound, preparation method therefor, and uses thereof | |
| EP3564215A4 (en) | Polyhydroxyphthalazinone compound, preparation method therefor and use thereof | |
| IL276410A (en) | Pyrazole compounds and preparation thereof | |
| EP4071170A4 (en) | Pharmaceutical composition, preparation method therefor and use thereof | |
| EP3666767A4 (en) | Pyridazinone compound, method for preparation thereof, pharmaceutical composition thereof, and use thereof |