SG11202011455SA - Codon optimization - Google Patents

Codon optimization

Info

Publication number
SG11202011455SA
SG11202011455SA SG11202011455SA SG11202011455SA SG11202011455SA SG 11202011455S A SG11202011455S A SG 11202011455SA SG 11202011455S A SG11202011455S A SG 11202011455SA SG 11202011455S A SG11202011455S A SG 11202011455SA SG 11202011455S A SG11202011455S A SG 11202011455SA
Authority
SG
Singapore
Prior art keywords
codon optimization
codon
optimization
Prior art date
Application number
SG11202011455SA
Inventor
Long Fan
Original Assignee
Nanjing Genscript Biotech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing Genscript Biotech Co Ltd filed Critical Nanjing Genscript Biotech Co Ltd
Publication of SG11202011455SA publication Critical patent/SG11202011455SA/en

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Databases & Information Systems (AREA)
  • Bioethics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Evolutionary Computation (AREA)
  • Public Health (AREA)
  • Software Systems (AREA)
  • Chemical & Material Sciences (AREA)
  • Data Mining & Analysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Artificial Intelligence (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
SG11202011455SA 2018-07-30 2019-07-30 Codon optimization SG11202011455SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2018097745 2018-07-30
PCT/CN2019/098258 WO2020024917A1 (en) 2018-07-30 2019-07-30 Codon optimization

Publications (1)

Publication Number Publication Date
SG11202011455SA true SG11202011455SA (en) 2020-12-30

Family

ID=69232314

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202011455SA SG11202011455SA (en) 2018-07-30 2019-07-30 Codon optimization

Country Status (8)

Country Link
US (1) US20210366574A1 (en)
EP (1) EP3830830A4 (en)
JP (1) JP2021532439A (en)
KR (1) KR20210037611A (en)
CN (1) CN112513989B (en)
SG (1) SG11202011455SA (en)
TW (1) TWI802728B (en)
WO (1) WO2020024917A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3177907A1 (en) * 2020-05-07 2021-11-11 Translate Bio, Inc. Generation of optimized nucleotide sequences
CN112735525B (en) * 2021-01-18 2023-12-26 苏州科锐迈德生物医药科技有限公司 mRNA sequence optimization method and device based on divide-and-conquer method
WO2022221576A1 (en) * 2021-04-14 2022-10-20 Opentrons LabWorks Inc. Methods for codon optimization and uses thereof
WO2023242343A1 (en) 2022-06-15 2023-12-21 Immunoscape Pte. Ltd. Human t cell receptors specific for antigenic peptides derived from mitogen-activated protein kinase 8 interacting protein 2 (mapk8ip2), epstein-barr virus or human endogenous retrovirus, and uses thereof
DE102022118459A1 (en) 2022-07-22 2024-01-25 Proteolutions UG (haftungsbeschränkt) METHOD FOR OPTIMIZING A NUCLEOTIDE SEQUENCE FOR EXPRESSING AN AMINO ACID SEQUENCE IN A TARGET ORGANISM
WO2024067780A1 (en) * 2022-09-30 2024-04-04 南京金斯瑞生物科技有限公司 Codon optimization for reducing immunogenicity of exogenous nucleic acids
CN116072231B (en) * 2022-10-17 2024-02-13 中国医学科学院病原生物学研究所 Method for optimally designing mRNA vaccine based on codon of amino acid sequence
CN115440300B (en) * 2022-11-07 2023-01-20 深圳市瑞吉生物科技有限公司 Codon sequence optimization method and device, computer equipment and storage medium
CN116168764B (en) * 2023-04-25 2023-06-30 深圳新合睿恩生物医疗科技有限公司 Method, device and equipment for optimizing 5' untranslated region sequence of messenger ribonucleic acid

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1987150T3 (en) * 2006-02-21 2011-10-31 Chromagenics Bv Selection of host cells expressing protein at high levels
WO2008000632A1 (en) * 2006-06-29 2008-01-03 Dsm Ip Assets B.V. A method for achieving improved polypeptide expression
US8326547B2 (en) * 2009-10-07 2012-12-04 Nanjingjinsirui Science & Technology Biology Corp. Method of sequence optimization for improved recombinant protein expression using a particle swarm optimization algorithm
CN102864141A (en) * 2012-09-13 2013-01-09 成都生物制品研究所有限责任公司 Method for constructing big-volume synonymous code bank and optimizing gene template
US20140244228A1 (en) * 2012-09-19 2014-08-28 Agency For Science, Technology And Research Codon optimization of a synthetic gene(s) for protein expression
EP4105337A1 (en) * 2014-09-09 2022-12-21 The Broad Institute, Inc. A droplet-based method and apparatus for composite single-cell nucleic acid analysis
US20170362627A1 (en) * 2014-11-10 2017-12-21 Modernatx, Inc. Multiparametric nucleic acid optimization
EP3050962A1 (en) * 2015-01-28 2016-08-03 Institut Pasteur RNA virus attenuation by alteration of mutational robustness and sequence space
WO2018104385A1 (en) * 2016-12-07 2018-06-14 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Codon optimization
CN106834313B (en) * 2017-02-21 2020-10-02 中国科学院亚热带农业生态研究所 Artificially optimized and synthesized Pat#Genes and recombinant vectors and methods for altering crop resistance
CN108363905B (en) * 2018-02-07 2019-03-08 南京晓庄学院 A kind of CodonPlant system and its remodeling method for the transformation of plant foreign gene

Also Published As

Publication number Publication date
CN112513989B (en) 2022-03-22
TWI802728B (en) 2023-05-21
EP3830830A1 (en) 2021-06-09
CN112513989A (en) 2021-03-16
EP3830830A4 (en) 2022-05-11
TW202008379A (en) 2020-02-16
WO2020024917A1 (en) 2020-02-06
KR20210037611A (en) 2021-04-06
US20210366574A1 (en) 2021-11-25
JP2021532439A (en) 2021-11-25

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