SG11202011084YA - Midscale model for organic growth and phasing - Google Patents

Midscale model for organic growth and phasing

Info

Publication number
SG11202011084YA
SG11202011084YA SG11202011084YA SG11202011084YA SG11202011084YA SG 11202011084Y A SG11202011084Y A SG 11202011084YA SG 11202011084Y A SG11202011084Y A SG 11202011084YA SG 11202011084Y A SG11202011084Y A SG 11202011084YA SG 11202011084Y A SG11202011084Y A SG 11202011084YA
Authority
SG
Singapore
Prior art keywords
midscale
phasing
model
organic growth
growth
Prior art date
Application number
SG11202011084YA
Inventor
John Gunst
Jonathan Fortin
Tristan Wilkins
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of SG11202011084YA publication Critical patent/SG11202011084YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/005—Incubators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/26—Inoculator or sampler
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/40—Manifolds; Distribution pieces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/26—Conditioning fluids entering or exiting the reaction vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12—Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M99/00—Subject matter not otherwise provided for in other groups of this subclass

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • General Factory Administration (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Treating Waste Gases (AREA)
SG11202011084YA 2018-06-01 2019-05-13 Midscale model for organic growth and phasing SG11202011084YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862679076P 2018-06-01 2018-06-01
PCT/US2019/031975 WO2019231652A2 (en) 2018-06-01 2019-05-13 Midscale model for organic growth and phasing

Publications (1)

Publication Number Publication Date
SG11202011084YA true SG11202011084YA (en) 2020-12-30

Family

ID=66669110

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202011084YA SG11202011084YA (en) 2018-06-01 2019-05-13 Midscale model for organic growth and phasing

Country Status (7)

Country Link
US (1) US20190367858A1 (en)
EP (1) EP3802771A2 (en)
JP (1) JP2021526372A (en)
KR (1) KR20210018872A (en)
CN (1) CN112204127A (en)
SG (1) SG11202011084YA (en)
WO (1) WO2019231652A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020112990A1 (en) * 2018-11-29 2020-06-04 Fluitec International Filter housings, purification skids and methods of use thereof
US20210197142A1 (en) * 2019-12-31 2021-07-01 Pall Corporation Buffer management system with manifold for bioprocessing system
KR102370142B1 (en) * 2020-03-23 2022-03-04 프레스티지바이오로직스 주식회사 Hybrid System of Culture and Purification Process for the Production of Antibody Pharmaceuticals
WO2022248623A1 (en) * 2021-05-26 2022-12-01 Simabs Nv Integrated continuous bioprocess production platform
CN114181287B (en) * 2021-12-10 2023-09-19 商丘美兰生物工程有限公司 Preparation method of DNA virus vaccine
WO2023167584A1 (en) * 2022-03-01 2023-09-07 Biosanapharma B.V. Continuous manufacturing of a biological substance with process traceability
WO2024006236A1 (en) * 2022-06-28 2024-01-04 Amgen Inc. Flexible facility configurations for therapeutic product manufacturing

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU632065B2 (en) 1988-09-23 1992-12-17 Novartis Vaccines And Diagnostics, Inc. Cell culture medium for enhanced cell growth, culture longevity and product expression
GB9022545D0 (en) 1990-10-17 1990-11-28 Wellcome Found Culture medium
GB2251249B (en) 1990-12-28 1995-06-21 Mogam Biotech Res Inst High-density medium for animal cell culture
DE69842245D1 (en) * 1997-12-24 2011-06-09 Abbott Biologicals Bv Preparation of cells for the production of biologics
CN101076347B (en) * 2004-09-30 2012-09-26 拜耳医药保健有限公司 Devices and methods for integrated continuous manufacturing of biological molecules
EP2280998A1 (en) * 2008-04-23 2011-02-09 Symphogen A/S Methods for manufacturing a polyclonal protein
WO2010069320A2 (en) * 2008-12-19 2010-06-24 Stobbe Tech A/S Biopharmaceutical plant in a column
EP2591349B1 (en) * 2010-07-07 2016-06-08 GE Healthcare Bio-Sciences AB Fluid mixing in a disposable fluid processing system
MX2015010637A (en) * 2013-02-26 2016-07-05 Heliae Dev Llc Modular tubular bioreactor.
RU2768003C2 (en) * 2013-03-08 2022-03-22 Джензим Корпорейшн Integrated continuous production of therapeutic protein-based medicinal agents
EP2994485B1 (en) * 2013-05-06 2018-01-10 Sanofi Continuous multistep process for purifying antibodies
US20150159127A1 (en) * 2013-05-10 2015-06-11 BioCapacity On Demand, LLC Mobile vessel or carrier for the manufacturing production, purification and sterile fill and finish of biologics
WO2015003012A2 (en) * 2013-07-01 2015-01-08 Olivier Berteau Distributed perfusion bioreactor system for continuous culture of biological cells
BR112016008032B1 (en) * 2013-10-14 2022-09-20 G-Con Manufacturing Inc CONNECTION UNIT AND METHOD FOR CONNECTING TWO OR MORE STRUCTURES WITH CONNECTION UNIT
WO2015095809A1 (en) * 2013-12-20 2015-06-25 Biogen Idec Ma Inc. Use of perfusion seed cultures to improve biopharmaceutical fed-batch production capacity and product quality
CN106232798B (en) * 2014-02-21 2019-06-07 生命科技股份有限公司 The system rehydrated for culture medium, method and apparatus
TWI776235B (en) * 2014-06-09 2022-09-01 美商健臻公司 Seed train processes and uses thereof
KR102439718B1 (en) * 2014-07-11 2022-09-02 지-콘 메뉴팩츄어링 인코포레이티드 Modular parts that supply utilities to cleanroom, isolation or containment cubicles, pods, or modules
CN108138101A (en) * 2015-07-29 2018-06-08 藻类研究中心公司 Light emitting diode bioreactor and application method
DE102015220315A1 (en) * 2015-10-19 2017-04-20 Krones Ag Fermentation tank and process
AU2017230823A1 (en) 2016-03-10 2018-09-27 Lonza Ltd Customizable facility
TWI808057B (en) 2016-06-24 2023-07-11 瑞士商隆沙有限公司 Variable diameter bioreactor vessel and system, method of producing a fermentation product using a reduced amount of reactors in a seed stage train and production reactor, and bioproduction facility
KR102480770B1 (en) * 2016-08-02 2022-12-22 론자 리미티드 Customizable facility
DE102017100150B3 (en) * 2017-01-05 2018-03-22 Sartorius Stedim Biotech Gmbh A method and apparatus arrangement for providing a large amount of cell culture medium using disposable components

Also Published As

Publication number Publication date
WO2019231652A2 (en) 2019-12-05
CN112204127A (en) 2021-01-08
WO2019231652A3 (en) 2020-01-09
JP2021526372A (en) 2021-10-07
US20190367858A1 (en) 2019-12-05
KR20210018872A (en) 2021-02-18
EP3802771A2 (en) 2021-04-14

Similar Documents

Publication Publication Date Title
SG11202011084YA (en) Midscale model for organic growth and phasing
EP3281161A4 (en) System and method for digital supply chain traceability
EP3334267A4 (en) Soil loosening and furrower assemblies and a bed renovator therefor
SG11202004615YA (en) A type of organic nanogrids and their nanopolymers as well as their preparation methods
EP3257372A4 (en) Method for cultivating oysters on land
IL285467A (en) Plant growing container and method
EP3504963A4 (en) Virus-resistant tobacco and breeding method therefor
GB2582718B (en) Fish farm
NO20171271A1 (en) Fish Farm
ZA202005805B (en) Natural mosquito repellant
HK1219393A1 (en) A tailor-made horseshoe and its manufacturing method
IL257038B (en) A modular lamp system for insect breeding, use thereof for stimulation of insect reproduction and a method of insect breeding
IL273045A (en) System and method for tree growth management
ZA201805599B (en) Method to reduce microbial bloom in poultry hatchery
EP3630705C0 (en) A method for conversion of poultry manure
GB201502821D0 (en) Structure with seed layer for controlling grain growth and crystallographic orientation
PT3772924T (en) Efficient land-based fish farm
PL3592923T3 (en) Wooden structure suitable as a living or office area and method for the production and placement thereof
PL3195713T3 (en) Method and manure distributor
GB201602503D0 (en) Fish tank and method
PT3772897T (en) Growing space for vertical farming
GB201714618D0 (en) Drag and biofouling growth reducing fabricfor aquaculture
GB201708413D0 (en) Incubator and method for use
GB201712679D0 (en) Hoof support and method
GB201704983D0 (en) Animal model