SG11202010742UA - Liquid depot for non-invasive sustained delivery of agents to the eye - Google Patents
Liquid depot for non-invasive sustained delivery of agents to the eyeInfo
- Publication number
- SG11202010742UA SG11202010742UA SG11202010742UA SG11202010742UA SG11202010742UA SG 11202010742U A SG11202010742U A SG 11202010742UA SG 11202010742U A SG11202010742U A SG 11202010742UA SG 11202010742U A SG11202010742U A SG 11202010742UA SG 11202010742U A SG11202010742U A SG 11202010742UA
- Authority
- SG
- Singapore
- Prior art keywords
- eye
- agents
- sustained delivery
- liquid depot
- invasive
- Prior art date
Links
- 239000007788 liquid Substances 0.000 title 1
- 230000002459 sustained effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862665367P | 2018-05-01 | 2018-05-01 | |
| PCT/US2019/030294 WO2019213330A1 (en) | 2018-05-01 | 2019-05-01 | Liquid depot for non-invasive sustained delivery of agents to the eye |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202010742UA true SG11202010742UA (en) | 2020-11-27 |
Family
ID=68386784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202010742UA SG11202010742UA (en) | 2018-05-01 | 2019-05-01 | Liquid depot for non-invasive sustained delivery of agents to the eye |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11234926B2 (en) |
| EP (1) | EP3787611A4 (en) |
| JP (1) | JP2021523223A (en) |
| KR (1) | KR20210003877A (en) |
| CN (1) | CN112367981B (en) |
| AU (1) | AU2019263302B2 (en) |
| BR (1) | BR112020022087A2 (en) |
| CA (1) | CA3097927A1 (en) |
| MX (1) | MX2020011536A (en) |
| SG (1) | SG11202010742UA (en) |
| WO (1) | WO2019213330A1 (en) |
| ZA (1) | ZA202006573B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019263302B2 (en) * | 2018-05-01 | 2024-06-27 | Chibi, Inc. | Liquid depot for non-invasive sustained delivery of agents to the eye |
| MX2020011535A (en) | 2018-05-01 | 2020-11-24 | Chibi Inc | Eye drop formulation and method for sustained delivery of medicament to the retina. |
| US20220125829A1 (en) * | 2020-10-28 | 2022-04-28 | Hovione Scientia Limited | Methods and compositions for treating meibomian gland dysfunction, dry eye disease, and related disorders |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003513019A (en) * | 1999-09-27 | 2003-04-08 | ソーナス ファーマシューティカルス，インコーポレイテッド | Composition of tocol-soluble therapeutic agent |
| US6331313B1 (en) | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| DE10030378A1 (en) * | 2000-06-21 | 2002-03-14 | Audit Inst For Medical Service | New pharmaceutical composition for topical application of water-insoluble and / or poorly water-soluble active ingredients |
| US8425929B2 (en) | 2004-04-30 | 2013-04-23 | Allergan, Inc. | Sustained release intraocular implants and methods for preventing retinal dysfunction |
| US8119154B2 (en) | 2004-04-30 | 2012-02-21 | Allergan, Inc. | Sustained release intraocular implants and related methods |
| US8236292B2 (en) | 2004-06-04 | 2012-08-07 | Camurus Ab | Liquid depot formulations |
| WO2006039336A2 (en) | 2004-10-01 | 2006-04-13 | Ramscor, Inc. | Conveniently implantable sustained release drug compositions |
| US9993558B2 (en) * | 2004-10-01 | 2018-06-12 | Ramscor, Inc. | Sustained release eye drop formulations |
| US8541413B2 (en) | 2004-10-01 | 2013-09-24 | Ramscor, Inc. | Sustained release eye drop formulations |
| US20080038316A1 (en) | 2004-10-01 | 2008-02-14 | Wong Vernon G | Conveniently implantable sustained release drug compositions |
| DE102005035986B4 (en) * | 2005-07-28 | 2009-10-15 | Bausch & Lomb Incorporated | Sterile drippable multiphase emulsifier-free ophthalmic preparation |
| TWI376239B (en) * | 2006-02-01 | 2012-11-11 | Andrew Xian Chen | Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof |
| US20090082337A1 (en) * | 2007-09-21 | 2009-03-26 | Srini Venkastesh | Compositions Comprising Quinolone and Methods for Treating or Controlling Infections |
| CN102238949A (en) | 2008-10-09 | 2011-11-09 | 拉姆斯科股份有限公司 | Composition and method for treating dry eye syndrome |
| IT1393419B1 (en) * | 2009-03-19 | 2012-04-20 | Medivis S R L | OPHTHALMIC COMPOSITIONS OF OMEGA-3 AND OMEGA-6 POLYSATURATED FATTY ACIDS. |
| IN2012DN06581A (en) * | 2010-03-17 | 2015-10-23 | Novaliq Gmbh | |
| BR112013004570A2 (en) * | 2010-09-03 | 2016-09-06 | Novagali Pharma Sa | water-in-oil emulsion to treat eye disease |
| WO2013058838A2 (en) * | 2011-06-10 | 2013-04-25 | Wong Vernon G | Conveniently injectable or implantable sustained-release antioxidant formulations for therapies of ocular maladies or cancer |
| EP2717914B1 (en) | 2011-06-10 | 2019-10-30 | Ramscor, Inc. | Sustained release formulations for delivery of proteins to the eye and methods of preparing same |
| EP2787975B1 (en) | 2011-12-05 | 2017-10-04 | Camurus AB | Robust controlled-release formulations |
| EP2790673B1 (en) * | 2011-12-16 | 2017-07-05 | Allergan, Inc. | Ophthalmic compositions comprising polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymers (soluplus) |
| JP5661067B2 (en) * | 2012-05-29 | 2015-01-28 | 株式会社ジェイアイエヌ | Eyewear |
| US11224660B2 (en) * | 2014-05-29 | 2022-01-18 | Radius Pharmaceuticals, Inc. | Stable cannabinoid formulations |
| TWI756168B (en) * | 2015-02-02 | 2022-03-01 | 日商參天製藥股份有限公司 | Polyaphrons and palpebral administration thereof |
| JP2016175900A (en) * | 2015-03-18 | 2016-10-06 | 参天製薬株式会社 | Sustained-release pharmaceutical composition |
| US10668011B2 (en) | 2016-06-30 | 2020-06-02 | Durect Corporation | Depot formulations |
| AU2019263302B2 (en) * | 2018-05-01 | 2024-06-27 | Chibi, Inc. | Liquid depot for non-invasive sustained delivery of agents to the eye |
| MX2020011535A (en) | 2018-05-01 | 2020-11-24 | Chibi Inc | Eye drop formulation and method for sustained delivery of medicament to the retina. |
-
2019
- 2019-05-01 AU AU2019263302A patent/AU2019263302B2/en active Active
- 2019-05-01 JP JP2021510274A patent/JP2021523223A/en active Pending
- 2019-05-01 SG SG11202010742UA patent/SG11202010742UA/en unknown
- 2019-05-01 CA CA3097927A patent/CA3097927A1/en active Pending
- 2019-05-01 BR BR112020022087-6A patent/BR112020022087A2/en unknown
- 2019-05-01 MX MX2020011536A patent/MX2020011536A/en unknown
- 2019-05-01 EP EP19795860.6A patent/EP3787611A4/en active Pending
- 2019-05-01 WO PCT/US2019/030294 patent/WO2019213330A1/en unknown
- 2019-05-01 KR KR1020207034068A patent/KR20210003877A/en active Search and Examination
- 2019-05-01 CN CN201980044591.3A patent/CN112367981B/en active Active
-
2020
- 2020-06-23 US US16/909,242 patent/US11234926B2/en active Active
- 2020-10-22 ZA ZA2020/06573A patent/ZA202006573B/en unknown
-
2021
- 2021-12-09 US US17/547,028 patent/US20220168219A1/en active Pending
-
2024
- 2024-04-30 US US18/650,914 patent/US20240285520A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US11234926B2 (en) | 2022-02-01 |
| US20200368152A1 (en) | 2020-11-26 |
| US20240285520A1 (en) | 2024-08-29 |
| WO2019213330A1 (en) | 2019-11-07 |
| AU2019263302A1 (en) | 2020-11-26 |
| CN112367981B (en) | 2024-06-04 |
| CN112367981A (en) | 2021-02-12 |
| EP3787611A1 (en) | 2021-03-10 |
| ZA202006573B (en) | 2023-05-31 |
| MX2020011536A (en) | 2020-11-24 |
| EP3787611A4 (en) | 2022-03-09 |
| US20220168219A1 (en) | 2022-06-02 |
| KR20210003877A (en) | 2021-01-12 |
| BR112020022087A2 (en) | 2021-02-02 |
| JP2021523223A (en) | 2021-09-02 |
| AU2019263302B2 (en) | 2024-06-27 |
| CA3097927A1 (en) | 2019-11-07 |
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