SG11202010125VA - Anti-complement component antibodies and methods of use - Google Patents

Anti-complement component antibodies and methods of use

Info

Publication number
SG11202010125VA
SG11202010125VA SG11202010125VA SG11202010125VA SG11202010125VA SG 11202010125V A SG11202010125V A SG 11202010125VA SG 11202010125V A SG11202010125V A SG 11202010125VA SG 11202010125V A SG11202010125V A SG 11202010125VA SG 11202010125V A SG11202010125V A SG 11202010125VA
Authority
SG
Singapore
Prior art keywords
methods
complement component
component antibodies
antibodies
complement
Prior art date
Application number
SG11202010125VA
Inventor
Taku Fukuzawa
Kenta Haraya
Wei Shiong Adrian Ho
Noriyuki Takahashi
Masaru Muraoka
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of SG11202010125VA publication Critical patent/SG11202010125VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
SG11202010125VA 2018-04-13 2019-04-12 Anti-complement component antibodies and methods of use SG11202010125VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018077527 2018-04-13
JP2018188770 2018-10-04
PCT/JP2019/015919 WO2019198807A1 (en) 2018-04-13 2019-04-12 Anti-complement component antibodies and methods of use

Publications (1)

Publication Number Publication Date
SG11202010125VA true SG11202010125VA (en) 2020-11-27

Family

ID=68164028

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202010125VA SG11202010125VA (en) 2018-04-13 2019-04-12 Anti-complement component antibodies and methods of use

Country Status (16)

Country Link
US (1) US20210198347A1 (en)
EP (1) EP3774892A4 (en)
JP (2) JP7333789B2 (en)
KR (1) KR20200143459A (en)
CN (1) CN112313249A (en)
AU (1) AU2019250403A1 (en)
BR (1) BR112020018357A2 (en)
CA (1) CA3094312A1 (en)
CL (2) CL2020002610A1 (en)
CR (1) CR20200542A (en)
IL (1) IL277827A (en)
MA (1) MA52248A (en)
MX (1) MX2020010528A (en)
PE (1) PE20201447A1 (en)
SG (1) SG11202010125VA (en)
WO (1) WO2019198807A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6774164B2 (en) 2012-08-24 2020-10-21 中外製薬株式会社 Mouse FcγRII specific Fc antibody
EP3783017A1 (en) 2013-04-02 2021-02-24 Chugai Seiyaku Kabushiki Kaisha Fc region variant
AU2020275348A1 (en) * 2019-05-15 2021-12-09 Chugai Seiyaku Kabushiki Kaisha An antigen-binding molecule, a pharmaceutical composition, and a method
AU2020368745A1 (en) * 2019-10-16 2022-04-21 Chugai Seiyaku Kabushiki Kaisha An antibody, a pharmaceutical composition, and a method
JP2023536904A (en) * 2020-08-06 2023-08-30 バイオベラティブ・ユーエスエイ・インコーポレイテッド Inflammatory Cytokines and Fatigue in Subjects With Complement-Mediated Disease
WO2022103871A1 (en) * 2020-11-10 2022-05-19 Wyomingv Immune, Inc. Therapeutic compositions for the treatment of covid-19
AR125344A1 (en) 2021-04-15 2023-07-05 Chugai Pharmaceutical Co Ltd ANTI-C1S ANTIBODY
US11958899B2 (en) 2021-07-13 2024-04-16 Mabwell Therapeutics Inc. Anti-C1s antibodies and uses thereof
CN117327732A (en) * 2022-12-31 2024-01-02 义翘神州(泰州)科技有限公司 Expression plasmid combination, expression host cell and expression method for fully self-cleaving recombinant C1s protein

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ602884A (en) 2008-04-11 2014-08-29 Chugai Pharmaceutical Co Ltd Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
HUP0900319A2 (en) * 2009-05-25 2011-01-28 Eotvos Lorand Tudomanyegyetem New peptides, method of producing therof and use thereof
TWI667346B (en) * 2010-03-30 2019-08-01 中外製藥股份有限公司 Antibodies with modified affinity to fcrn that promote antigen clearance
CA3214532A1 (en) * 2012-06-18 2013-12-27 Omeros Corporation Compositions and methods of inhibiting masp-1 and/or masp-2 and/or masp-3 for the treatment of various diseases and disorders
US20160053023A1 (en) * 2013-04-09 2016-02-25 Annexon, Inc. Methods of treatment for neuromyelitis optica
EP2997045A4 (en) * 2013-05-15 2016-11-23 Annexon Inc Anti-complement factor c1s antibodies and uses thereof
KR102626877B1 (en) * 2014-11-05 2024-01-19 애넥슨, 인코포레이티드 Humanized Anti-Complement Factor C1Q Antibodies and Uses Thereof
BR112017021289A2 (en) * 2015-04-06 2018-06-26 Bioverativ Usa Inc humanized anti-c1s antibodies and methods of use
CN108779171B (en) * 2015-11-24 2022-07-05 安尼艾克松股份有限公司 FAB fragment of anti-complement factor C1Q and application thereof

Also Published As

Publication number Publication date
JP2021521206A (en) 2021-08-26
AU2019250403A1 (en) 2020-11-19
JP7333789B2 (en) 2023-08-25
MA52248A (en) 2021-02-17
BR112020018357A2 (en) 2020-12-29
PE20201447A1 (en) 2020-12-10
CL2020002610A1 (en) 2021-02-12
EP3774892A1 (en) 2021-02-17
IL277827A (en) 2020-11-30
CA3094312A1 (en) 2019-10-17
CL2023001793A1 (en) 2023-12-15
MX2020010528A (en) 2020-11-06
US20210198347A1 (en) 2021-07-01
CN112313249A (en) 2021-02-02
WO2019198807A1 (en) 2019-10-17
EP3774892A4 (en) 2022-02-16
JP2023154049A (en) 2023-10-18
CR20200542A (en) 2021-01-18
KR20200143459A (en) 2020-12-23

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