SG11202009930PA - Microfluidic method for single cell analysis - Google Patents

Microfluidic method for single cell analysis

Info

Publication number
SG11202009930PA
SG11202009930PA SG11202009930PA SG11202009930PA SG11202009930PA SG 11202009930P A SG11202009930P A SG 11202009930PA SG 11202009930P A SG11202009930P A SG 11202009930PA SG 11202009930P A SG11202009930P A SG 11202009930PA SG 11202009930P A SG11202009930P A SG 11202009930PA
Authority
SG
Singapore
Prior art keywords
single cell
cell analysis
microfluidic method
microfluidic
analysis
Prior art date
Application number
SG11202009930PA
Inventor
Annabelle Gérard
Vera Menrath
Original Assignee
Hifibio Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hifibio Sas filed Critical Hifibio Sas
Publication of SG11202009930PA publication Critical patent/SG11202009930PA/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Measuring Cells (AREA)
SG11202009930PA 2018-04-18 2019-04-18 Microfluidic method for single cell analysis SG11202009930PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18168084.4A EP3556466A1 (en) 2018-04-18 2018-04-18 Microfluidic method for single cell analysis
PCT/EP2019/060210 WO2019202135A1 (en) 2018-04-18 2019-04-18 Microfluidic method for single cell analysis

Publications (1)

Publication Number Publication Date
SG11202009930PA true SG11202009930PA (en) 2020-11-27

Family

ID=62116200

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202009930PA SG11202009930PA (en) 2018-04-18 2019-04-18 Microfluidic method for single cell analysis

Country Status (9)

Country Link
US (2) US11904317B2 (en)
EP (2) EP3556466A1 (en)
JP (1) JP7315581B2 (en)
CN (2) CN115792228A (en)
AU (2) AU2019254674A1 (en)
CA (1) CA3097276C (en)
IL (1) IL278022A (en)
SG (1) SG11202009930PA (en)
WO (1) WO2019202135A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112798785A (en) * 2019-11-13 2021-05-14 中国科学院大连化学物理研究所 Chip capable of realizing cell capture and multi-index biological analysis and application
WO2023019583A1 (en) * 2021-08-20 2023-02-23 深圳华大生命科学研究院 Method for detecting and sorting antigen-specific t-cell receptor with high throughput
CN114062679B (en) * 2021-11-16 2023-09-08 中国科学院上海微系统与信息技术研究所 Single-cell secretion high-flux detection method and system based on droplet microfluidic
CN114062688A (en) * 2021-12-29 2022-02-18 中山大学附属第五医院 CCL8 protein as biomarker of non-obstructive azoospermia and application thereof
CN118556076A (en) * 2022-01-17 2024-08-27 深圳华大生命科学研究院 Method for obtaining nanobody information of specific recognition antigen
WO2023188896A1 (en) * 2022-03-29 2023-10-05 ソニーグループ株式会社 Bioparticle analysis system, information processing device, and bioparticle analysis method
CN117907594A (en) * 2024-03-15 2024-04-19 墨卓生物科技(浙江)有限公司 Method for high-throughput screening and analysis of yeast single cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010042744A1 (en) 2008-10-08 2010-04-15 Universite De Strasbourg Microfluidic devices for reliable on-chip incubation of droplets in delay lines
WO2011112827A2 (en) * 2010-03-12 2011-09-15 The General Hospital Corporation Amplifying rare cell surface markers
WO2013134261A1 (en) 2012-03-05 2013-09-12 President And Fellows Of Harvard College Systems and methods for epigenetic sequencing
FR3027396B1 (en) * 2014-10-15 2016-11-25 Espci Innov METHOD FOR ANALYZING DROP CONTENT AND ASSOCIATED APPARATUS

Also Published As

Publication number Publication date
US20240253045A1 (en) 2024-08-01
WO2019202135A1 (en) 2019-10-24
CN112165989B (en) 2022-12-09
CN115792228A (en) 2023-03-14
EP3556466A1 (en) 2019-10-23
JP2021521456A (en) 2021-08-26
CA3097276C (en) 2023-11-21
CN112165989A (en) 2021-01-01
CA3097276A1 (en) 2019-10-24
IL278022A (en) 2020-11-30
US20210146366A1 (en) 2021-05-20
EP3781315A1 (en) 2021-02-24
JP7315581B2 (en) 2023-07-26
AU2019254674A1 (en) 2020-12-03
AU2023241386A1 (en) 2023-10-26
US11904317B2 (en) 2024-02-20

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