SG11202008804UA - Pharmaceutical compositions having high drug loadings of medium chain triglycerides and methods related thereto - Google Patents

Pharmaceutical compositions having high drug loadings of medium chain triglycerides and methods related thereto

Info

Publication number
SG11202008804UA
SG11202008804UA SG11202008804UA SG11202008804UA SG11202008804UA SG 11202008804U A SG11202008804U A SG 11202008804UA SG 11202008804U A SG11202008804U A SG 11202008804UA SG 11202008804U A SG11202008804U A SG 11202008804UA SG 11202008804U A SG11202008804U A SG 11202008804UA
Authority
SG
Singapore
Prior art keywords
pharmaceutical compositions
medium chain
chain triglycerides
methods related
high drug
Prior art date
Application number
SG11202008804UA
Inventor
Taryn Boivin
Devon B Dubose
Samuel T Henderson
Christi Lynn Hostetler
David K Lyon
Craig A Sather
Matthew J Shaffer
Original Assignee
Cerecin Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerecin Inc filed Critical Cerecin Inc
Publication of SG11202008804UA publication Critical patent/SG11202008804UA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1664Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
SG11202008804UA 2018-03-15 2019-03-15 Pharmaceutical compositions having high drug loadings of medium chain triglycerides and methods related thereto SG11202008804UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862643479P 2018-03-15 2018-03-15
PCT/US2019/022478 WO2019178482A1 (en) 2018-03-15 2019-03-15 Pharmaceutical compositions having high drug loadings of medium chain triglycerides and methods related thereto

Publications (1)

Publication Number Publication Date
SG11202008804UA true SG11202008804UA (en) 2020-10-29

Family

ID=67908469

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202008804UA SG11202008804UA (en) 2018-03-15 2019-03-15 Pharmaceutical compositions having high drug loadings of medium chain triglycerides and methods related thereto

Country Status (14)

Country Link
US (1) US20210186915A1 (en)
EP (1) EP3765002A4 (en)
JP (2) JP2021518355A (en)
KR (1) KR20200132950A (en)
CN (1) CN112566629B (en)
AU (1) AU2019236238A1 (en)
BR (1) BR112020018765A2 (en)
CA (1) CA3093703A1 (en)
EA (1) EA202092092A1 (en)
IL (1) IL277251A (en)
PH (1) PH12020551470A1 (en)
SG (1) SG11202008804UA (en)
WO (1) WO2019178482A1 (en)
ZA (1) ZA202005701B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018170235A1 (en) 2017-03-15 2018-09-20 Accera, Inc. Pharmaceutical compositions having high drug loadings of medium chain triglycerides and methods related thereto

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2775441B1 (en) * 1998-02-27 2000-04-28 Serobiologiques Lab Sa MATRIX FOR THE PREPARATION OF MICROPARTICLES OR NANOPARTICLES, PROCESS FOR PRODUCING SUCH PARTICLES AND PARTICLES OBTAINED
TR200103188T2 (en) * 1999-05-07 2002-04-22 Pharmasol Gmbh Lipid particles based on liquid and solid lipid mixtures.
US20080009467A1 (en) * 2000-05-01 2008-01-10 Accera, Inc. Combinations of medium chain triglycerides and therapeutic agents for the treatment and prevention of alzheimers disease and other diseases resulting from reduced neuronal metabolism
US20020006959A1 (en) * 2000-05-01 2002-01-17 Henderson Samuel T. Use of medium chain triglycerides for the treatment and prevention of Alzheimer's Disease and other diseases resulting from reduced Neuronal Metabolism
JP6619744B2 (en) * 2014-02-11 2019-12-11 ファーネクストPharnext Combination of baclofen, acamprosate, and medium chain triglycerides for the treatment of neurological disorders
SG11201700530PA (en) * 2014-07-23 2017-02-27 Food Science Inst Foundation Agent for improving brain function and agent for preventing or treating cognitive impairment
US20190070124A1 (en) * 2016-03-04 2019-03-07 Sharon Anavi-Goffer Compositions of cb2 receptor selective agonists for treatment of mental disorders

Also Published As

Publication number Publication date
EA202092092A1 (en) 2021-02-15
JP2021518355A (en) 2021-08-02
IL277251A (en) 2020-10-29
EP3765002A1 (en) 2021-01-20
CA3093703A1 (en) 2019-09-19
BR112020018765A2 (en) 2020-12-29
EP3765002A4 (en) 2021-12-15
KR20200132950A (en) 2020-11-25
JP2024045146A (en) 2024-04-02
WO2019178482A1 (en) 2019-09-19
PH12020551470A1 (en) 2021-09-01
US20210186915A1 (en) 2021-06-24
ZA202005701B (en) 2022-07-27
CN112566629A (en) 2021-03-26
CN112566629B (en) 2023-11-17
AU2019236238A1 (en) 2020-10-08

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