SG11202008519RA - Heterocyclic compound and use thereof - Google Patents

Heterocyclic compound and use thereof

Info

Publication number
SG11202008519RA
SG11202008519RA SG11202008519RA SG11202008519RA SG11202008519RA SG 11202008519R A SG11202008519R A SG 11202008519RA SG 11202008519R A SG11202008519R A SG 11202008519RA SG 11202008519R A SG11202008519R A SG 11202008519RA SG 11202008519R A SG11202008519R A SG 11202008519RA
Authority
SG
Singapore
Prior art keywords
heterocyclic compound
heterocyclic
compound
Prior art date
Application number
SG11202008519RA
Inventor
Yuya Oguro
Shigemitsu Matsumoto
Takeshi Wakabayashi
Norihito Tokunaga
Taku Kamei
Mitsuhiro Ito
Satoshi Mikami
Masaki Seto
Shinji Morimoto
Shinji Nakamura
Sachie Takashima
Masataka Murakami
Masaki Daini
Makoto Kamata
Minoru Nakamura
Yasufumi Wada
Hiroyuki Kakei
Kazuaki Takami
Taisuke Tawaraishi
Jumpei Aida
Kouichi Iwanaga
Satoshi Yamamoto
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of SG11202008519RA publication Critical patent/SG11202008519RA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41881,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/5025Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833Encapsulating processes; Filling of capsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11202008519RA 2018-03-28 2019-03-27 Heterocyclic compound and use thereof SG11202008519RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018062939 2018-03-28
PCT/JP2019/014901 WO2019189945A1 (en) 2018-03-28 2019-03-27 Heterocyclic compound and use thereof

Publications (1)

Publication Number Publication Date
SG11202008519RA true SG11202008519RA (en) 2020-10-29

Family

ID=66397395

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202008519RA SG11202008519RA (en) 2018-03-28 2019-03-27 Heterocyclic compound and use thereof

Country Status (16)

Country Link
US (2) US10807987B2 (en)
EP (1) EP3774800A1 (en)
JP (1) JP7279067B2 (en)
KR (1) KR20200136957A (en)
CN (1) CN111936495A (en)
AR (1) AR115020A1 (en)
AU (1) AU2019241765B2 (en)
BR (1) BR112020018238A2 (en)
CA (1) CA3100133A1 (en)
EA (1) EA202092294A1 (en)
IL (1) IL276912A (en)
MA (1) MA52214A (en)
MX (1) MX2020010148A (en)
SG (1) SG11202008519RA (en)
TW (1) TW202003519A (en)
WO (1) WO2019189945A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3660003B1 (en) 2017-07-28 2024-01-24 Takeda Pharmaceutical Company Limited Heterocyclic compound
MX2020010148A (en) * 2018-03-28 2020-12-07 Takeda Pharmaceuticals Co Heterocyclic compound and use thereof.
JP2021050161A (en) 2019-09-25 2021-04-01 武田薬品工業株式会社 Heterocyclic compound and use thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492382A1 (en) * 1980-10-22 1982-04-23 Synthelabo IMIDAZO (1,2-A) PYRIDINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF
US5252563A (en) * 1991-12-19 1993-10-12 G. D. Searle & Company 5,6,7,8-tetrahydro-imidazo[1,2-a]pyrimidine compounds for treatment of neurotoxic injury
JP3439551B2 (en) * 1994-11-08 2003-08-25 富士写真フイルム株式会社 Silver halide photographic materials
ATE218583T1 (en) 1995-03-14 2002-06-15 Praecis Pharm Inc COMPOUNDS WITH AGGREGATION-MODULATING EFFECTS ON AMYLOID PROTEIN
EP1586584A1 (en) 1996-08-27 2005-10-19 Praecis Pharmaceuticals Incorporated Modulators of beta-amyloid peptide aggregation comprising D-amino acids
US6331640B1 (en) 1998-10-13 2001-12-18 Hoffmann-La Roche Inc. Diaminopropionic acid derivatives
US6545127B1 (en) 1999-06-28 2003-04-08 Oklahoma Medical Research Foundation Catalytically active recombinant memapsin and methods of use thereof
WO2002080928A1 (en) * 2001-04-03 2002-10-17 Merck & Co., Inc. N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists
JP2004161716A (en) * 2002-11-15 2004-06-10 Takeda Chem Ind Ltd Jnk inhibitor
WO2004089366A1 (en) * 2003-04-10 2004-10-21 Pfizer Japan, Inc. Bicyclic compounds as nr2b receptor antagonists
JP2009507795A (en) 2005-08-31 2009-02-26 スミスクライン ビーチャム コーポレーション Compound
SG173584A1 (en) * 2009-02-06 2011-09-29 Elan Pharm Inc Inhibitors of jun n-terminal kinase
US8404859B2 (en) 2011-03-16 2013-03-26 Hoffmann-La Roche Inc. Thiazole and thiophene compounds
CA2832291C (en) * 2011-04-05 2015-12-01 Pfizer Limited Pyrrolo[2,3-d)pyrimidine tropomyosin-related kinase inhibitors
FR2998892B1 (en) 2012-12-04 2015-01-02 Pf Medicament AMINOCYCLOBUTANE DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR USE AS MEDICAMENTS
WO2014172044A1 (en) 2013-03-15 2014-10-23 Epizyme, Inc. Substituted benzene compounds
US9243001B2 (en) 2013-03-15 2016-01-26 Epizyme, Inc. Substituted benzene compounds
WO2016104434A1 (en) 2014-12-24 2016-06-30 武田薬品工業株式会社 Heterocyclic compound
JP6827757B2 (en) 2016-10-11 2021-02-10 鬼怒川ゴム工業株式会社 Weather strip mounting clip
EP3660003B1 (en) 2017-07-28 2024-01-24 Takeda Pharmaceutical Company Limited Heterocyclic compound
MX2020010148A (en) * 2018-03-28 2020-12-07 Takeda Pharmaceuticals Co Heterocyclic compound and use thereof.
WO2020153414A1 (en) 2019-01-24 2020-07-30 武田薬品工業株式会社 Heterocyclic compound and use thereof
WO2020196828A1 (en) 2019-03-28 2020-10-01 武田薬品工業株式会社 Nitrogen-containing heterocyclic compound

Also Published As

Publication number Publication date
IL276912A (en) 2020-10-29
MX2020010148A (en) 2020-12-07
WO2019189945A8 (en) 2020-10-15
EA202092294A1 (en) 2021-01-15
US11702419B2 (en) 2023-07-18
AU2019241765A8 (en) 2021-02-18
US10807987B2 (en) 2020-10-20
US20210332053A1 (en) 2021-10-28
AU2019241765A1 (en) 2020-11-12
AU2019241765B2 (en) 2022-07-07
WO2019189945A1 (en) 2019-10-03
MA52214A (en) 2021-04-21
CA3100133A1 (en) 2019-10-03
EP3774800A1 (en) 2021-02-17
AR115020A1 (en) 2020-11-18
US20190300536A1 (en) 2019-10-03
BR112020018238A2 (en) 2020-12-29
JP2021519294A (en) 2021-08-10
TW202003519A (en) 2020-01-16
KR20200136957A (en) 2020-12-08
JP7279067B2 (en) 2023-05-22
CN111936495A (en) 2020-11-13

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