SG11202007927WA - Anti-cd73 antibodies and methods of use thereof - Google Patents

Anti-cd73 antibodies and methods of use thereof

Info

Publication number
SG11202007927WA
SG11202007927WA SG11202007927WA SG11202007927WA SG11202007927WA SG 11202007927W A SG11202007927W A SG 11202007927WA SG 11202007927W A SG11202007927W A SG 11202007927WA SG 11202007927W A SG11202007927W A SG 11202007927WA SG 11202007927W A SG11202007927W A SG 11202007927WA
Authority
SG
Singapore
Prior art keywords
antibodies
methods
Prior art date
Application number
SG11202007927WA
Inventor
Nicholas Stuart Wilson
Jeremy Dale Waight
Shawn Michael Jennings
Olga Ignatovich
Emmanuel Cyrille Pascal Briend
Benjamin Maxime Morin
Oliver Schon
Spencer Campbell
Original Assignee
Agenus Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agenus Inc filed Critical Agenus Inc
Publication of SG11202007927WA publication Critical patent/SG11202007927WA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202007927WA 2018-03-09 2019-03-08 Anti-cd73 antibodies and methods of use thereof SG11202007927WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862640850P 2018-03-09 2018-03-09
PCT/US2019/021313 WO2019173692A2 (en) 2018-03-09 2019-03-08 Anti-cd73 antibodies and methods of use thereof

Publications (1)

Publication Number Publication Date
SG11202007927WA true SG11202007927WA (en) 2020-09-29

Family

ID=65904555

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202007927WA SG11202007927WA (en) 2018-03-09 2019-03-08 Anti-cd73 antibodies and methods of use thereof

Country Status (19)

Country Link
US (2) US11692042B2 (en)
EP (1) EP3762421A2 (en)
JP (2) JP7319992B2 (en)
KR (1) KR20200130403A (en)
CN (1) CN112074535A (en)
AR (1) AR114275A1 (en)
AU (2) AU2019231791B2 (en)
BR (1) BR112020017382A2 (en)
CA (1) CA3093468A1 (en)
CL (1) CL2020002314A1 (en)
CR (1) CR20200392A (en)
EA (1) EA202091710A1 (en)
IL (1) IL276731A (en)
MX (1) MX2020009394A (en)
PE (1) PE20210628A1 (en)
PH (1) PH12020551317A1 (en)
SG (1) SG11202007927WA (en)
TW (1) TWI823906B (en)
WO (1) WO2019173692A2 (en)

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WO2019173692A3 (en) 2019-11-14
AU2019231791A1 (en) 2020-09-03
TWI823906B (en) 2023-12-01
WO2019173692A2 (en) 2019-09-12
JP7319992B2 (en) 2023-08-02
EP3762421A2 (en) 2021-01-13
CL2020002314A1 (en) 2021-03-05
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US20230416397A1 (en) 2023-12-28
EA202091710A1 (en) 2021-02-16
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CN112074535A (en) 2020-12-11
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BR112020017382A2 (en) 2021-01-26
AU2022259823A1 (en) 2022-12-01
US20190352418A1 (en) 2019-11-21
KR20200130403A (en) 2020-11-18
IL276731A (en) 2020-09-30
AR114275A1 (en) 2020-08-12
CR20200392A (en) 2020-11-17
JP2021515559A (en) 2021-06-24
US11692042B2 (en) 2023-07-04
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TW201945391A (en) 2019-12-01
AU2019231791B2 (en) 2022-08-11

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