SG11202007854QA - Gan-cnn for mhc peptide binding prediction - Google Patents

Gan-cnn for mhc peptide binding prediction

Info

Publication number
SG11202007854QA
SG11202007854QA SG11202007854QA SG11202007854QA SG11202007854QA SG 11202007854Q A SG11202007854Q A SG 11202007854QA SG 11202007854Q A SG11202007854Q A SG 11202007854QA SG 11202007854Q A SG11202007854Q A SG 11202007854QA SG 11202007854Q A SG11202007854Q A SG 11202007854QA
Authority
SG
Singapore
Prior art keywords
cnn
gan
peptide binding
mhc peptide
binding prediction
Prior art date
Application number
SG11202007854QA
Inventor
Xingjian Wang
Ying Huang
Wei Wang
Qi Zhao
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of SG11202007854QA publication Critical patent/SG11202007854QA/en

Links

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20Supervised data analysis
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/04Architecture, e.g. interconnection topology
    • G06N3/0464Convolutional networks [CNN, ConvNet]
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/08Learning methods
    • G06N3/094Adversarial learning
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/30Detection of binding sites or motifs
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10Sequence alignment; Homology search
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/30Prediction of properties of chemical compounds, compositions or mixtures
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/40Searching chemical structures or physicochemical data
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/50Molecular design, e.g. of drugs
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/70Machine learning, data mining or chemometrics
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/90Programming languages; Computing architectures; Database systems; Data warehousing
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C60/00Computational materials science, i.e. ICT specially adapted for investigating the physical or chemical properties of materials or phenomena associated with their design, synthesis, processing, characterisation or utilisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C99/00Subject matter not provided for in other groups of this subclass
SG11202007854QA 2018-02-17 2019-02-18 Gan-cnn for mhc peptide binding prediction SG11202007854QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862631710P 2018-02-17 2018-02-17
PCT/US2019/018434 WO2019161342A1 (en) 2018-02-17 2019-02-18 Gan-cnn for mhc peptide binding prediction

Publications (1)

Publication Number Publication Date
SG11202007854QA true SG11202007854QA (en) 2020-09-29

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202007854QA SG11202007854QA (en) 2018-02-17 2019-02-18 Gan-cnn for mhc peptide binding prediction

Country Status (11)

Country Link
US (1) US20190259474A1 (en)
EP (1) EP3753022A1 (en)
JP (2) JP7047115B2 (en)
KR (2) KR20230164757A (en)
CN (1) CN112119464A (en)
AU (2) AU2019221793B2 (en)
CA (1) CA3091480A1 (en)
IL (1) IL276730B1 (en)
MX (1) MX2020008597A (en)
SG (1) SG11202007854QA (en)
WO (1) WO2019161342A1 (en)

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US11704573B2 (en) * 2019-03-25 2023-07-18 Here Global B.V. Method, apparatus, and computer program product for identifying and compensating content contributors
US20200379814A1 (en) * 2019-05-29 2020-12-03 Advanced Micro Devices, Inc. Computer resource scheduling using generative adversarial networks
KR20220019778A (en) * 2019-06-12 2022-02-17 퀀텀-에스아이 인코포레이티드 Techniques and related systems and methods for protein identification using machine learning
CN110598786B (en) * 2019-09-09 2022-01-07 京东方科技集团股份有限公司 Neural network training method, semantic classification method and semantic classification device
CN110875790A (en) * 2019-11-19 2020-03-10 上海大学 Wireless channel modeling implementation method based on generation countermeasure network
US20210150270A1 (en) * 2019-11-19 2021-05-20 International Business Machines Corporation Mathematical function defined natural language annotation
JP2023501126A (en) * 2019-11-22 2023-01-18 エフ.ホフマン-ラ ロシュ アーゲー Multi-instance learner for tissue image classification
AU2020403134B2 (en) * 2019-12-12 2024-01-04 Just-Evotec Biologics, Inc. Generating protein sequences using machine learning techniques based on template protein sequences
CN111063391B (en) * 2019-12-20 2023-04-25 海南大学 Non-culturable microorganism screening system based on generation type countermeasure network principle
CN111402113B (en) * 2020-03-09 2021-10-15 北京字节跳动网络技术有限公司 Image processing method, image processing device, electronic equipment and computer readable medium
EP4128248A1 (en) * 2020-03-23 2023-02-08 Genentech, Inc. Estimating pharmacokinetic parameters using deep learning
US20210295173A1 (en) * 2020-03-23 2021-09-23 Samsung Electronics Co., Ltd. Method and apparatus for data-free network quantization and compression with adversarial knowledge distillation
US10885387B1 (en) * 2020-08-04 2021-01-05 SUPERB Al CO., LTD. Methods for training auto-labeling device and performing auto-labeling by using hybrid classification and devices using the same
US10902291B1 (en) * 2020-08-04 2021-01-26 Superb Ai Co., Ltd. Methods for training auto labeling device and performing auto labeling related to segmentation while performing automatic verification by using uncertainty scores and devices using the same
US20230253067A1 (en) * 2020-08-28 2023-08-10 Just-Evotec Biologics, Inc. Implementing a generative machine learning architecture to produce training data for a classification model
CN112597705B (en) * 2020-12-28 2022-05-24 哈尔滨工业大学 Multi-feature health factor fusion method based on SCVNN
CN112309497B (en) * 2020-12-28 2021-04-02 武汉金开瑞生物工程有限公司 Method and device for predicting protein structure based on Cycle-GAN
KR102519341B1 (en) * 2021-03-18 2023-04-06 재단법인한국조선해양기자재연구원 Early detection system for uneven tire wear by real-time noise analysis and method thereof
US20220328127A1 (en) * 2021-04-05 2022-10-13 Nec Laboratories America, Inc. Peptide based vaccine generation system with dual projection generative adversarial networks
US20220319635A1 (en) * 2021-04-05 2022-10-06 Nec Laboratories America, Inc. Generating minority-class examples for training data
US20230083313A1 (en) * 2021-09-13 2023-03-16 Nec Laboratories America, Inc. Peptide search system for immunotherapy
KR102507111B1 (en) * 2022-03-29 2023-03-07 주식회사 네오젠티씨 Apparatus and method for determining reliability of immunopeptidome information

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US8121797B2 (en) * 2007-01-12 2012-02-21 Microsoft Corporation T-cell epitope prediction
US9805305B2 (en) * 2015-08-07 2017-10-31 Yahoo Holdings, Inc. Boosted deep convolutional neural networks (CNNs)
US11291532B2 (en) 2016-07-27 2022-04-05 James R. Glidewell Dental Ceramics, Inc. Dental CAD automation using deep learning
CN106845471A (en) * 2017-02-20 2017-06-13 深圳市唯特视科技有限公司 A kind of vision significance Forecasting Methodology based on generation confrontation network
CN107590518A (en) 2017-08-14 2018-01-16 华南理工大学 A kind of confrontation network training method of multiple features study

Also Published As

Publication number Publication date
MX2020008597A (en) 2020-12-11
JP7459159B2 (en) 2024-04-01
KR20230164757A (en) 2023-12-04
US20190259474A1 (en) 2019-08-22
WO2019161342A1 (en) 2019-08-22
JP2022101551A (en) 2022-07-06
EP3753022A1 (en) 2020-12-23
JP7047115B2 (en) 2022-04-04
AU2019221793B2 (en) 2022-09-15
IL276730A (en) 2020-09-30
RU2020130420A (en) 2022-03-17
KR20200125948A (en) 2020-11-05
KR102607567B1 (en) 2023-12-01
JP2021514086A (en) 2021-06-03
AU2019221793A1 (en) 2020-09-17
CN112119464A (en) 2020-12-22
AU2022221568A1 (en) 2022-09-22
IL276730B1 (en) 2024-04-01
RU2020130420A3 (en) 2022-03-17
CA3091480A1 (en) 2019-08-22

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