SG11202007485PA - Atr inhibitor and application thereof - Google Patents

Atr inhibitor and application thereof

Info

Publication number
SG11202007485PA
SG11202007485PA SG11202007485PA SG11202007485PA SG11202007485PA SG 11202007485P A SG11202007485P A SG 11202007485PA SG 11202007485P A SG11202007485P A SG 11202007485PA SG 11202007485P A SG11202007485P A SG 11202007485PA SG 11202007485P A SG11202007485P A SG 11202007485PA
Authority
SG
Singapore
Prior art keywords
application
atr inhibitor
atr
inhibitor
Prior art date
Application number
SG11202007485PA
Inventor
Wenyuan Qian
Jian Wang
Jie Li
Jian Li
Shuhui Chen
Original Assignee
Shijiazhuang Sagacity New Drug Development Company Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shijiazhuang Sagacity New Drug Development Company Ltd filed Critical Shijiazhuang Sagacity New Drug Development Company Ltd
Publication of SG11202007485PA publication Critical patent/SG11202007485PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
SG11202007485PA 2018-02-07 2019-02-02 Atr inhibitor and application thereof SG11202007485PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201810124494 2018-02-07
CN201811361512 2018-11-15
PCT/CN2019/074578 WO2019154365A1 (en) 2018-02-07 2019-02-02 Atr inhibitor and application thereof

Publications (1)

Publication Number Publication Date
SG11202007485PA true SG11202007485PA (en) 2020-09-29

Family

ID=67548753

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202007485PA SG11202007485PA (en) 2018-02-07 2019-02-02 Atr inhibitor and application thereof

Country Status (18)

Country Link
US (1) US11434232B2 (en)
EP (1) EP3753937B1 (en)
JP (1) JP7290651B2 (en)
CN (1) CN111712499B (en)
AU (1) AU2019217388C1 (en)
BR (1) BR112020016020A8 (en)
CA (1) CA3090330A1 (en)
DK (1) DK3753937T3 (en)
FI (1) FI3753937T3 (en)
HR (1) HRP20240161T1 (en)
IL (1) IL276489A (en)
LT (1) LT3753937T (en)
PL (1) PL3753937T3 (en)
PT (1) PT3753937T (en)
RS (1) RS65147B1 (en)
SG (1) SG11202007485PA (en)
SI (1) SI3753937T1 (en)
WO (1) WO2019154365A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI778366B (en) * 2019-06-06 2022-09-21 中國商北京泰德製藥股份有限公司 2,4,6-Trisubstituted Pyrimidine Compounds as ATR Kinase Inhibitors
AU2020325416A1 (en) * 2019-08-06 2022-02-03 Wuxi Biocity Biopharmaceutics Co., Ltd. Crystalline form of ATR inhibitor and use thereof
JP2023528289A (en) * 2020-05-20 2023-07-04 北京泰徳製薬股▲フン▼有限公司 2,4,6-Trisubstituted Pyrimidine Compounds as ATR Kinase Inhibitors
US20230212165A1 (en) * 2020-05-29 2023-07-06 Shenzhen Lingfang Biotech Co., Ltd. Fluoropyrrolopyridine compound and application thereof
KR20230043109A (en) * 2020-06-24 2023-03-30 아스트라제네카 유케이 리미티드 Combinations of antibody-drug conjugates and ATR inhibitors
CN116134022A (en) * 2020-07-03 2023-05-16 上海德琪医药科技有限公司 ATR inhibitors and uses thereof
CN116178366A (en) * 2021-11-26 2023-05-30 深圳市瓴方生物医药科技有限公司 Crystal forms of fluoropyridine pyrrole compound and preparation method thereof
WO2023131234A1 (en) * 2022-01-06 2023-07-13 Shanghai Antengene Corporation Limited Crystalline forms of an atr inhibitor
WO2023215133A1 (en) * 2022-05-02 2023-11-09 AcuraStem Incorporated Pikfyve kinase inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009093981A1 (en) * 2008-01-23 2009-07-30 S Bio Pte Ltd Triazine compounds as kinase inhibitors
GB2465405A (en) 2008-11-10 2010-05-19 Univ Basel Triazine, pyrimidine and pyridine analogues and their use in therapy
US20110053923A1 (en) * 2008-12-22 2011-03-03 Astrazeneca Chemical compounds 610
SA111320519B1 (en) 2010-06-11 2014-07-02 Astrazeneca Ab Pyrimidinyl Compounds for Use as ATR Inhibitors
WO2012101654A2 (en) 2011-01-25 2012-08-02 Sphaera Pharma Pvt. Ltd Novel triazine compounds
AR095443A1 (en) 2013-03-15 2015-10-14 Fundación Centro Nac De Investig Oncológicas Carlos Iii HEREROCICLES CONDENSED WITH ACTION ON ATR
TWI700283B (en) 2014-08-04 2020-08-01 德商拜耳製藥公司 2-(morpholin-4-yl)-1,7-naphthyridines
CN111655688B (en) * 2017-09-08 2023-09-29 蓝谷制药有限责任公司 Substituted pyrrolopyridines as ATR inhibitors

Also Published As

Publication number Publication date
AU2019217388A1 (en) 2020-09-03
BR112020016020A2 (en) 2020-12-08
PL3753937T3 (en) 2024-04-02
RS65147B1 (en) 2024-02-29
CN111712499A (en) 2020-09-25
US11434232B2 (en) 2022-09-06
CA3090330A1 (en) 2019-08-15
LT3753937T (en) 2024-02-26
JP2021512908A (en) 2021-05-20
FI3753937T3 (en) 2024-01-31
DK3753937T3 (en) 2024-02-12
BR112020016020A8 (en) 2023-04-25
AU2019217388C1 (en) 2024-03-07
EP3753937A4 (en) 2021-07-07
EP3753937A1 (en) 2020-12-23
AU2019217388B2 (en) 2023-11-09
US20200399260A1 (en) 2020-12-24
CN111712499B (en) 2023-06-02
HRP20240161T1 (en) 2024-04-12
EP3753937B1 (en) 2024-01-10
RU2020128324A3 (en) 2022-03-09
WO2019154365A1 (en) 2019-08-15
PT3753937T (en) 2024-02-06
SI3753937T1 (en) 2024-03-29
RU2020128324A (en) 2022-03-09
IL276489A (en) 2020-09-30
JP7290651B2 (en) 2023-06-13

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