SG11202007438SA - System and method for fluid flow management in a bioprocessing system - Google Patents

System and method for fluid flow management in a bioprocessing system

Info

Publication number
SG11202007438SA
SG11202007438SA SG11202007438SA SG11202007438SA SG11202007438SA SG 11202007438S A SG11202007438S A SG 11202007438SA SG 11202007438S A SG11202007438S A SG 11202007438SA SG 11202007438S A SG11202007438S A SG 11202007438SA SG 11202007438S A SG11202007438S A SG 11202007438SA
Authority
SG
Singapore
Prior art keywords
fluid flow
flow management
bioprocessing
bioprocessing system
management
Prior art date
Application number
SG11202007438SA
Inventor
Weston Griffin
Alex Corwin
Xiaohua Zhang
Reginald Smith
Zhen Liu
Chengkun Zhang
Vandana Keskar
Brian Michael Davis
Kashan Shaikh
Original Assignee
Global Life Sciences Solutions Usa Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/893,336 external-priority patent/US10889792B2/en
Application filed by Global Life Sciences Solutions Usa Llc filed Critical Global Life Sciences Solutions Usa Llc
Publication of SG11202007438SA publication Critical patent/SG11202007438SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/24—Gas permeable parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
SG11202007438SA 2018-02-09 2019-02-08 System and method for fluid flow management in a bioprocessing system SG11202007438SA (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US15/893,336 US10889792B2 (en) 2018-02-09 2018-02-09 Cell expansion vessel systems and methods
US201862736143P 2018-09-25 2018-09-25
US201862736144P 2018-09-25 2018-09-25
US201862736154P 2018-09-25 2018-09-25
US201862736115P 2018-09-25 2018-09-25
US201862736120P 2018-09-25 2018-09-25
US201862736130P 2018-09-25 2018-09-25
US201862736125P 2018-09-25 2018-09-25
PCT/EP2019/053211 WO2019155032A1 (en) 2018-02-09 2019-02-08 System and method for fluid flow management in a bioprocessing system

Publications (1)

Publication Number Publication Date
SG11202007438SA true SG11202007438SA (en) 2020-09-29

Family

ID=65433651

Family Applications (6)

Application Number Title Priority Date Filing Date
SG11202007425YA SG11202007425YA (en) 2018-02-09 2019-02-08 Bioprocessing apparatus
SG11202007140XA SG11202007140XA (en) 2018-02-09 2019-02-08 Bioprocessing methods for cell therapy
SG11202007435RA SG11202007435RA (en) 2018-02-09 2019-02-08 Disposable kit for bioprocessing
SG11202007430UA SG11202007430UA (en) 2018-02-09 2019-02-08 Bioprocessing vessel
SG11202007438SA SG11202007438SA (en) 2018-02-09 2019-02-08 System and method for fluid flow management in a bioprocessing system
SG11202007439TA SG11202007439TA (en) 2018-02-09 2019-02-08 Systems and methods for bioprocessing

Family Applications Before (4)

Application Number Title Priority Date Filing Date
SG11202007425YA SG11202007425YA (en) 2018-02-09 2019-02-08 Bioprocessing apparatus
SG11202007140XA SG11202007140XA (en) 2018-02-09 2019-02-08 Bioprocessing methods for cell therapy
SG11202007435RA SG11202007435RA (en) 2018-02-09 2019-02-08 Disposable kit for bioprocessing
SG11202007430UA SG11202007430UA (en) 2018-02-09 2019-02-08 Bioprocessing vessel

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11202007439TA SG11202007439TA (en) 2018-02-09 2019-02-08 Systems and methods for bioprocessing

Country Status (10)

Country Link
EP (8) EP3749741A1 (en)
JP (10) JP7322041B2 (en)
KR (6) KR20200120665A (en)
CN (9) CN112041423A (en)
AU (6) AU2019219292A1 (en)
BR (1) BR112020015746A2 (en)
CA (7) CA3090447A1 (en)
MX (1) MX2020008317A (en)
SG (6) SG11202007425YA (en)
WO (8) WO2019155033A1 (en)

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AU2019219241A1 (en) 2020-08-13
RU2020126463A (en) 2022-03-09
WO2019155027A1 (en) 2019-08-15
CN112041420A (en) 2020-12-04
KR20200119277A (en) 2020-10-19
SG11202007430UA (en) 2020-09-29
AU2019219292A1 (en) 2020-08-27
CA3089953A1 (en) 2019-08-15
AU2019219294A1 (en) 2020-08-13
CA3090047A1 (en) 2019-08-15
JP2024024050A (en) 2024-02-21
CA3090447A1 (en) 2019-08-15
SG11202007439TA (en) 2020-09-29
KR20200120665A (en) 2020-10-21
JP7403906B2 (en) 2023-12-25
WO2019155030A1 (en) 2019-08-15
EP3749749A1 (en) 2020-12-16
CN112041423A (en) 2020-12-04
CA3090001A1 (en) 2019-08-15
CA3089925A1 (en) 2019-08-15
CN111936613A (en) 2020-11-13
MX2020008317A (en) 2020-11-24
JP7479693B2 (en) 2024-05-09
KR20200120664A (en) 2020-10-21
EP3749744A1 (en) 2020-12-16
JP2023138556A (en) 2023-10-02
WO2019155033A1 (en) 2019-08-15
WO2019155031A3 (en) 2019-09-26
JP2021513349A (en) 2021-05-27
JP2021512628A (en) 2021-05-20
JP7314151B2 (en) 2023-07-25
JP7322041B2 (en) 2023-08-07
EP3749743A1 (en) 2020-12-16
SG11202007140XA (en) 2020-08-28
SG11202007435RA (en) 2020-09-29
KR20200118835A (en) 2020-10-16
CN111954710A (en) 2020-11-17
CN112055744A (en) 2020-12-08
AU2019219293A1 (en) 2020-08-13
AU2019219291A1 (en) 2020-08-13
CN117821360A (en) 2024-04-05
CN112004921A (en) 2020-11-27
EP3749748A1 (en) 2020-12-16
CN112020552A (en) 2020-12-01
EP3749746A2 (en) 2020-12-16
JP2023133326A (en) 2023-09-22
EP3749741A1 (en) 2020-12-16
WO2019155029A1 (en) 2019-08-15
AU2019219295A1 (en) 2020-08-13
JP2021512633A (en) 2021-05-20
JP2021513350A (en) 2021-05-27
CA3089788A1 (en) 2019-08-15
SG11202007425YA (en) 2020-09-29
KR20200120666A (en) 2020-10-21
EP3749742A1 (en) 2020-12-16
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