SG11202007414XA - Osimertinib for use in the treatment of non-small cell lung cancer - Google Patents
Osimertinib for use in the treatment of non-small cell lung cancerInfo
- Publication number
- SG11202007414XA SG11202007414XA SG11202007414XA SG11202007414XA SG11202007414XA SG 11202007414X A SG11202007414X A SG 11202007414XA SG 11202007414X A SG11202007414X A SG 11202007414XA SG 11202007414X A SG11202007414X A SG 11202007414XA SG 11202007414X A SG11202007414X A SG 11202007414XA
- Authority
- SG
- Singapore
- Prior art keywords
- osimertinib
- treatment
- lung cancer
- small cell
- cell lung
- Prior art date
Links
- 208000002154 non-small cell lung carcinoma Diseases 0.000 title 1
- DUYJMQONPNNFPI-UHFFFAOYSA-N osimertinib Chemical compound COC1=CC(N(C)CCN(C)C)=C(NC(=O)C=C)C=C1NC1=NC=CC(C=2C3=CC=CC=C3N(C)C=2)=N1 DUYJMQONPNNFPI-UHFFFAOYSA-N 0.000 title 1
- 229960003278 osimertinib Drugs 0.000 title 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862629166P | 2018-02-12 | 2018-02-12 | |
| PCT/EP2019/053311 WO2019155059A1 (en) | 2018-02-12 | 2019-02-11 | Osimertinib for use in the treatment of non-small cell lung cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202007414XA true SG11202007414XA (en) | 2020-09-29 |
Family
ID=65443828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202007414XA SG11202007414XA (en) | 2018-02-12 | 2019-02-11 | Osimertinib for use in the treatment of non-small cell lung cancer |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US20200368231A1 (en) |
| EP (1) | EP3752153A1 (en) |
| JP (2) | JP2021513517A (en) |
| KR (1) | KR20200119243A (en) |
| CN (2) | CN111683663A (en) |
| AU (2) | AU2019219304A1 (en) |
| BR (1) | BR112020015507A2 (en) |
| CA (1) | CA3090010A1 (en) |
| EA (1) | EA202091841A1 (en) |
| IL (1) | IL276406A (en) |
| MA (1) | MA51823A (en) |
| MX (1) | MX2020008395A (en) |
| SG (1) | SG11202007414XA (en) |
| TW (1) | TW201941773A (en) |
| WO (1) | WO2019155059A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110433296A (en) * | 2019-08-16 | 2019-11-12 | 哈尔滨医科大学 | It is a kind of19F-MR/ fluorescence multi-mode molecular imaging and the diagnosis and treatment integration nano-probe and preparation method and application for carrying medicine |
| US20230056604A1 (en) * | 2020-01-20 | 2023-02-23 | Astrazeneca Ab | Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of cancer |
| WO2022120197A1 (en) * | 2020-12-03 | 2022-06-09 | Emory University | Combinations of epidermal growth factor receptor inhibitors and sterol regulatory element-binding protein inhibitors for uses in cancer therapies |
| CN114917231A (en) * | 2022-05-27 | 2022-08-19 | 杭州师范大学 | Application of beta-elemene and oxitinib medicine composition in preparing anti-lung cancer medicine |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2900230T3 (en) | 2011-07-27 | 2022-03-16 | Astrazeneca Ab | 2-(2,4,5-anilino substituted)pyrimidine compounds |
| GB201400034D0 (en) | 2014-01-02 | 2014-02-19 | Astrazeneca Ab | Pharmaceutical Compositions comprising AZD9291 |
| AU2015313811A1 (en) * | 2014-09-08 | 2017-04-06 | Yeda Research And Development Co. Ltd. | Compositions and methods for treating cancer resistant to a tyrosine kinase inhibitor (TKI) |
| EP3453392A4 (en) * | 2016-05-17 | 2020-03-04 | Japanese Foundation For Cancer Research | Therapeutic agent for lung cancer that has acquired egfr-tki resistance |
-
2019
- 2019-02-11 MA MA051823A patent/MA51823A/en unknown
- 2019-02-11 CA CA3090010A patent/CA3090010A1/en active Pending
- 2019-02-11 KR KR1020207022313A patent/KR20200119243A/en active Search and Examination
- 2019-02-11 SG SG11202007414XA patent/SG11202007414XA/en unknown
- 2019-02-11 MX MX2020008395A patent/MX2020008395A/en unknown
- 2019-02-11 BR BR112020015507-1A patent/BR112020015507A2/en unknown
- 2019-02-11 EP EP19705720.1A patent/EP3752153A1/en active Pending
- 2019-02-11 EA EA202091841A patent/EA202091841A1/en unknown
- 2019-02-11 TW TW108104348A patent/TW201941773A/en unknown
- 2019-02-11 WO PCT/EP2019/053311 patent/WO2019155059A1/en unknown
- 2019-02-11 CN CN201980012384.XA patent/CN111683663A/en active Pending
- 2019-02-11 CN CN202310971255.1A patent/CN116870008A/en active Pending
- 2019-02-11 US US16/968,912 patent/US20200368231A1/en not_active Abandoned
- 2019-02-11 AU AU2019219304A patent/AU2019219304A1/en not_active Abandoned
- 2019-02-11 JP JP2020541872A patent/JP2021513517A/en active Pending
-
2020
- 2020-07-30 IL IL276406A patent/IL276406A/en unknown
-
2021
- 2021-10-27 US US17/512,153 patent/US20220184076A1/en not_active Abandoned
-
2022
- 2022-05-05 AU AU2022203007A patent/AU2022203007A1/en active Pending
-
2023
- 2023-03-28 US US18/191,219 patent/US20230226059A1/en not_active Abandoned
- 2023-05-26 JP JP2023087054A patent/JP2023116537A/en active Pending
-
2024
- 2024-01-16 US US18/413,349 patent/US20240156815A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20200368231A1 (en) | 2020-11-26 |
| EP3752153A1 (en) | 2020-12-23 |
| IL276406A (en) | 2020-09-30 |
| CN116870008A (en) | 2023-10-13 |
| MX2020008395A (en) | 2020-09-21 |
| BR112020015507A2 (en) | 2021-01-26 |
| AU2019219304A1 (en) | 2020-09-24 |
| JP2023116537A (en) | 2023-08-22 |
| US20230226059A1 (en) | 2023-07-20 |
| CN111683663A (en) | 2020-09-18 |
| WO2019155059A1 (en) | 2019-08-15 |
| AU2022203007A1 (en) | 2022-05-26 |
| CA3090010A1 (en) | 2019-08-15 |
| TW201941773A (en) | 2019-11-01 |
| US20220184076A1 (en) | 2022-06-16 |
| US20240156815A1 (en) | 2024-05-16 |
| MA51823A (en) | 2021-05-19 |
| KR20200119243A (en) | 2020-10-19 |
| EA202091841A1 (en) | 2020-10-28 |
| JP2021513517A (en) | 2021-05-27 |
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