SG11202007241WA - Nucleic acid antibody constructs for use against respiratory syncytial virus - Google Patents

Nucleic acid antibody constructs for use against respiratory syncytial virus

Info

Publication number
SG11202007241WA
SG11202007241WA SG11202007241WA SG11202007241WA SG11202007241WA SG 11202007241W A SG11202007241W A SG 11202007241WA SG 11202007241W A SG11202007241W A SG 11202007241WA SG 11202007241W A SG11202007241W A SG 11202007241WA SG 11202007241W A SG11202007241W A SG 11202007241WA
Authority
SG
Singapore
Prior art keywords
nucleic acid
respiratory syncytial
syncytial virus
antibody constructs
use against
Prior art date
Application number
SG11202007241WA
Inventor
David Weiner
Kar Muthumani
Jing Chen
Trevor Smith
Katherine Schultheis
Original Assignee
Wistar Inst
Inovio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wistar Inst, Inovio Pharmaceuticals Inc filed Critical Wistar Inst
Publication of SG11202007241WA publication Critical patent/SG11202007241WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027Paramyxoviridae, e.g. respiratory syncytial virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
SG11202007241WA 2018-01-31 2019-01-31 Nucleic acid antibody constructs for use against respiratory syncytial virus SG11202007241WA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862624320P 2018-01-31 2018-01-31
US201862749580P 2018-10-23 2018-10-23
PCT/US2019/015975 WO2019152600A1 (en) 2018-01-31 2019-01-31 Nucleic acid antibody constructs for use against respiratory syncytial virus

Publications (1)

Publication Number Publication Date
SG11202007241WA true SG11202007241WA (en) 2020-08-28

Family

ID=67478343

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202007241WA SG11202007241WA (en) 2018-01-31 2019-01-31 Nucleic acid antibody constructs for use against respiratory syncytial virus

Country Status (11)

Country Link
US (1) US20210047390A1 (en)
EP (1) EP3746474A4 (en)
JP (1) JP2021512600A (en)
KR (1) KR20200140799A (en)
CN (1) CN111936513A (en)
AU (1) AU2019215006A1 (en)
BR (1) BR112020015588A2 (en)
CA (1) CA3089717A1 (en)
MX (1) MX2020008062A (en)
SG (1) SG11202007241WA (en)
WO (1) WO2019152600A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230111264A (en) * 2016-11-07 2023-07-25 더 위스타 인스티튜트 오브 아나토미 앤드 바이올로지 Dna antibody constructs for use against lyme disease

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0853487T3 (en) * 1995-09-18 2000-10-23 Us Health Neutralizing monoclonal antibodies against respiratory syncytial virus
JP2005524389A (en) * 2001-11-26 2005-08-18 イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー Enhanced electrical gene transfer of nucleic acid molecules into host tissues
GB0306618D0 (en) * 2003-03-22 2003-04-30 Univ Newcastle Antibody
JP5734985B2 (en) * 2009-09-17 2015-06-17 バクスター・ヘルスケヤー・ソシエテ・アノニムBaxter Healthcare SA Stable co-formulations of hyaluronidase and immunoglobulin and methods for their use
US8568726B2 (en) * 2009-10-06 2013-10-29 Medimmune Limited RSV specific binding molecule
NZ718973A (en) * 2010-07-09 2019-01-25 Janssen Vaccines & Prevention Bv Anti-human respiratory syncytial virus (rsv) antibodies and methods of use
TWI659968B (en) * 2013-03-14 2019-05-21 再生元醫藥公司 Human antibodies to respiratory syncytial virus f protein and methods of use thereof
SG11201604719WA (en) * 2013-12-13 2016-07-28 Univ Pennsylvania Dna antibody constructs and method of using same
EP4353316A2 (en) * 2014-01-15 2024-04-17 Medimmune Limited Rsv-specific antibodies and functional parts thereof
CN107847588B (en) * 2015-05-20 2021-12-28 免疫功坊股份有限公司 Molecular construct with targeting and effector moieties and uses thereof
JO3555B1 (en) * 2015-10-29 2020-07-05 Merck Sharp & Dohme Antibody neutralizing human respiratory syncytial virus
EA201892525A1 (en) * 2016-05-05 2019-04-30 Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания DNA ANTIBODY DESIGNS FOR USE AGAINST PSEUDOMONAS AERUGINOSA

Also Published As

Publication number Publication date
EP3746474A1 (en) 2020-12-09
CA3089717A1 (en) 2019-08-08
KR20200140799A (en) 2020-12-16
EP3746474A4 (en) 2021-12-15
BR112020015588A2 (en) 2021-01-05
WO2019152600A1 (en) 2019-08-08
US20210047390A1 (en) 2021-02-18
AU2019215006A1 (en) 2020-09-17
CN111936513A (en) 2020-11-13
MX2020008062A (en) 2020-12-03
JP2021512600A (en) 2021-05-20

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