SG11202007219PA - Peptide macrocycles against acinetobacter baumannii - Google Patents
Peptide macrocycles against acinetobacter baumanniiInfo
- Publication number
- SG11202007219PA SG11202007219PA SG11202007219PA SG11202007219PA SG11202007219PA SG 11202007219P A SG11202007219P A SG 11202007219PA SG 11202007219P A SG11202007219P A SG 11202007219PA SG 11202007219P A SG11202007219P A SG 11202007219PA SG 11202007219P A SG11202007219P A SG 11202007219PA
- Authority
- SG
- Singapore
- Prior art keywords
- acinetobacter baumannii
- against acinetobacter
- peptide macrocycles
- macrocycles against
- peptide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2018/084131 | 2018-04-23 | ||
| PCT/EP2019/060272 WO2019206853A1 (en) | 2018-04-23 | 2019-04-23 | Peptide macrocycles against acinetobacter baumannii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202007219PA true SG11202007219PA (en) | 2020-08-28 |
Family
ID=66290410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202007219PA SG11202007219PA (en) | 2018-04-23 | 2019-04-23 | Peptide macrocycles against acinetobacter baumannii |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US11819532B2 (en) |
| EP (1) | EP3784262A1 (en) |
| JP (2) | JP7460541B2 (en) |
| KR (1) | KR20210005574A (en) |
| CN (1) | CN111886020B (en) |
| AR (1) | AR114290A1 (en) |
| AU (1) | AU2019260124A1 (en) |
| BR (1) | BR112020021729A2 (en) |
| CA (1) | CA3089688A1 (en) |
| CL (1) | CL2020002695A1 (en) |
| CR (1) | CR20200488A (en) |
| IL (2) | IL278053B1 (en) |
| MA (1) | MA52352A (en) |
| MX (1) | MX2020007633A (en) |
| PE (1) | PE20210855A1 (en) |
| PH (1) | PH12020551762A1 (en) |
| SG (1) | SG11202007219PA (en) |
| UA (1) | UA126943C2 (en) |
| WO (1) | WO2019206853A1 (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY193014A (en) | 2015-10-27 | 2022-09-22 | Hoffmann La Roche | Peptide macrocycles against acinetobacter baumannii |
| US11505573B2 (en) | 2018-03-28 | 2022-11-22 | Hoffmann-La Roche Inc. | Peptide macrocycles against Acinetobacter baumannii |
| LT3784663T (en) | 2018-04-23 | 2023-10-25 | Celgene Corporation | Substituted 4-aminoisoindoline-1,3-dione compounds and their use for treating lymphoma |
| US11819532B2 (en) * | 2018-04-23 | 2023-11-21 | Hoffmann-La Roche Inc. | Peptide macrocycles against Acinetobacter baumannii |
| JP2022525029A (en) | 2019-03-08 | 2022-05-11 | エフ．ホフマン－ラ ロシュ アーゲー | New imidazole-pyrazole derivative |
| WO2021148420A1 (en) | 2020-01-22 | 2021-07-29 | F. Hoffmann-La Roche Ag | Novel heterocyclic compounds |
| CN115485279A (en) | 2020-04-29 | 2022-12-16 | 豪夫迈·罗氏有限公司 | Antibacterial 8-phenylamino-3- (pyrazol-4-yl) imidazo [1,2-a ] pyrazine derivatives |
| CN115667266A (en) | 2020-06-01 | 2023-01-31 | 豪夫迈·罗氏有限公司 | Novel imidazopyrazine derivatives |
| CN115667264A (en) | 2020-06-08 | 2023-01-31 | 豪夫迈·罗氏有限公司 | Novel imidazo-pyrazine derivatives |
| EP4161931A1 (en) | 2020-06-09 | 2023-04-12 | F. Hoffmann-La Roche AG | Novel imidazopyrazine derivatives |
| JP2023538969A (en) | 2020-08-31 | 2023-09-12 | エフ． ホフマン－ラ ロシュ アーゲー | Imidazole-pyrazole derivatives as antibacterial agents |
| WO2022049011A1 (en) | 2020-09-01 | 2022-03-10 | F. Hoffmann-La Roche Ag | Imidazole-pyrazole derivatives with anti-bacterial properties |
| CN116096709A (en) | 2020-09-07 | 2023-05-09 | 豪夫迈·罗氏有限公司 | Novel heterocyclic antibiotics |
| EP4288424A1 (en) | 2021-02-07 | 2023-12-13 | F. Hoffmann-La Roche AG | Novel heteroaryl-substituted imidazole derivatives |
| WO2023280733A1 (en) | 2021-07-06 | 2023-01-12 | F. Hoffmann-La Roche Ag | Quaternary ammonium cation substituted compounds for the treatment of bacterial infections |
| WO2023285497A1 (en) | 2021-07-15 | 2023-01-19 | F. Hoffmann-La Roche Ag | Imidazole derivatives and their use as antibiotics |
| TW202342493A (en) * | 2022-02-14 | 2023-11-01 | 瑞士商赫孚孟拉羅股份公司 | Process for manufacturing macrocyclic peptides |
| WO2023161316A1 (en) | 2022-02-25 | 2023-08-31 | F. Hoffmann-La Roche Ag | Zwitterionic antibacterial compounds |
| WO2023194418A1 (en) | 2022-04-07 | 2023-10-12 | F. Hoffmann-La Roche Ag | Crystalline forms of a macrocyclic peptide antibiotic |
| WO2024033278A1 (en) | 2022-08-09 | 2024-02-15 | F. Hoffmann-La Roche Ag | Process for manufacturing an antibiotic macrocyclic peptide |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6660832B1 (en) | 1999-08-20 | 2003-12-09 | Isis Pharmaceuticals, Inc. | Macrocyclic compounds and preparation methods thereof |
| DE10226921A1 (en) | 2002-06-17 | 2003-12-24 | Bayer Ag | Antibacterial amide macrocycles |
| DE10234422A1 (en) | 2002-07-29 | 2004-02-12 | Bayer Ag | Antibacterial ester macrocycles |
| JP4791183B2 (en) | 2002-08-23 | 2011-10-12 | スローン−ケッタリング インスティトュート フォア キャンサー リサーチ | Synthesis and use of epothilone, its intermediates and analogues |
| WO2004111077A1 (en) | 2003-06-18 | 2004-12-23 | Tranzyme Pharma Inc. | Macrocyclic antagonists of the motilin receptor |
| US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
| US7491695B2 (en) | 2003-06-18 | 2009-02-17 | Tranzyme Pharma Inc. | Methods of using macrocyclic modulators of the ghrelin receptor |
| EP1498422A1 (en) | 2003-07-17 | 2005-01-19 | Jerini AG | C5a Receptor Antagonists |
| US7550431B2 (en) | 2003-07-31 | 2009-06-23 | Tranzyme Pharma Inc. | Spatially-defined macrocycles incorporating peptide bond surrogates |
| DK1648922T3 (en) | 2003-07-31 | 2011-03-14 | Tranzyme Pharma Inc | Spatially defined macrocyclic compounds useful for drug discovery |
| JP2008502583A (en) | 2003-10-01 | 2008-01-31 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | Antibacterial amide macrocycle |
| EP1737884B1 (en) | 2004-03-19 | 2016-10-19 | The University Of Queensland | Alpha helical mimics, their uses and methods for their production |
| DE102004025731A1 (en) | 2004-05-26 | 2005-12-15 | Bayer Healthcare Ag | Antibacterial amide macrocycles III |
| US20060004185A1 (en) | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| KR20070104355A (en) | 2005-01-17 | 2007-10-25 | 제리니 아게 | C5a receptor antagonists |
| DE102005014245A1 (en) | 2005-03-30 | 2006-10-05 | Aicuris Gmbh & Co. Kg | Antibacterial amide macrocycles V |
| GB0609492D0 (en) | 2006-05-15 | 2006-06-21 | Angeletti P Ist Richerche Bio | Therapeutic agents |
| EP2118091B1 (en) | 2007-02-08 | 2015-04-15 | Janssen Sciences Ireland UC | Pyrimidine substituted macrocyclic hcv inhibitors |
| BRPI0907754A2 (en) | 2008-02-08 | 2015-07-21 | Aileron Therapeutics Inc | Therapeutic peptidomimetic macrocycles |
| US8338565B2 (en) | 2008-08-20 | 2012-12-25 | Ensemble Therapeutics Corporation | Macrocyclic compounds for inhibition of tumor necrosis factor alpha |
| JP2013508409A (en) | 2009-10-23 | 2013-03-07 | トランザイム・ファーマ，インコーポレイテッド | Macrocyclic inhibitors of serine protease enzymes |
| CN102812037A (en) | 2009-10-30 | 2012-12-05 | 特兰齐姆制药公司 | Macrocyclic Ghrelin Receptor Antagonists And Inverse Agonists And Methods Of Using The Same |
| RU2582678C2 (en) | 2010-08-13 | 2016-04-27 | Эйлерон Терапьютикс, Инк. | Peptidomimetic macrocycles |
| AU2012301605A1 (en) | 2011-08-31 | 2014-04-17 | New York University | Thioether-,ether-, and alkylamine-linked hydrogen bond surrogate pertidomimentics |
| JP6450191B2 (en) | 2012-02-15 | 2019-01-09 | エイルロン セラピューティクス，インコーポレイテッド | Peptide mimetic macrocycle |
| CN103387601B (en) | 2012-05-11 | 2017-01-11 | 南开大学 | Anti-dengue virus (DENV) heterocyclic peptide compounds and preparing methods and uses thereof |
| WO2014048976A1 (en) * | 2012-09-25 | 2014-04-03 | Vaxdyn Sl | Anti-acinetobacter baumannii immunogens |
| WO2014081886A1 (en) | 2012-11-21 | 2014-05-30 | Rqx Pharmaceuticals, Inc. | Macrocyclic broad spectrum antibiotics |
| US9493510B2 (en) | 2013-01-10 | 2016-11-15 | Noliva Therapeutics Llc | Peptidomimetic compounds |
| EP2942389A1 (en) * | 2014-05-05 | 2015-11-11 | Servicio Andaluz De Salud | Vaccine against Acinetobacter baumannii based on lipopolysaccharide-deficient cellular components |
| RU2017101154A (en) | 2014-07-30 | 2018-08-30 | Абак Терапьютикс, С.Л. | Arylhydrazides containing a 2-pyridone moiety as selective antimicrobial agents |
| MY193014A (en) * | 2015-10-27 | 2022-09-22 | Hoffmann La Roche | Peptide macrocycles against acinetobacter baumannii |
| EP3388444A1 (en) | 2017-04-10 | 2018-10-17 | F. Hoffmann-La Roche AG | Anti-bacterial peptide macrocycles and use thereof |
| US11505573B2 (en) | 2018-03-28 | 2022-11-22 | Hoffmann-La Roche Inc. | Peptide macrocycles against Acinetobacter baumannii |
| US11819532B2 (en) * | 2018-04-23 | 2023-11-21 | Hoffmann-La Roche Inc. | Peptide macrocycles against Acinetobacter baumannii |
-
2019
- 2019-04-19 US US16/389,292 patent/US11819532B2/en active Active
- 2019-04-23 CA CA3089688A patent/CA3089688A1/en active Pending
- 2019-04-23 IL IL278053A patent/IL278053B1/en unknown
- 2019-04-23 AU AU2019260124A patent/AU2019260124A1/en active Pending
- 2019-04-23 CN CN201980020627.4A patent/CN111886020B/en active Active
- 2019-04-23 KR KR1020207029322A patent/KR20210005574A/en unknown
- 2019-04-23 UA UAA202007319A patent/UA126943C2/en unknown
- 2019-04-23 AR ARP190101064A patent/AR114290A1/en unknown
- 2019-04-23 SG SG11202007219PA patent/SG11202007219PA/en unknown
- 2019-04-23 IL IL309537A patent/IL309537A/en unknown
- 2019-04-23 WO PCT/EP2019/060272 patent/WO2019206853A1/en unknown
- 2019-04-23 CR CR20200488A patent/CR20200488A/en unknown
- 2019-04-23 MA MA052352A patent/MA52352A/en unknown
- 2019-04-23 MX MX2020007633A patent/MX2020007633A/en unknown
- 2019-04-23 EP EP19719814.6A patent/EP3784262A1/en active Pending
- 2019-04-23 JP JP2020558432A patent/JP7460541B2/en active Active
- 2019-04-23 PE PE2020000996A patent/PE20210855A1/en unknown
- 2019-04-23 BR BR112020021729-8A patent/BR112020021729A2/en unknown
-
2020
- 2020-10-16 CL CL2020002695A patent/CL2020002695A1/en unknown
- 2020-10-23 PH PH12020551762A patent/PH12020551762A1/en unknown
-
2023
- 2023-10-12 US US18/379,626 patent/US20240050516A1/en active Pending
-
2024
- 2024-01-26 JP JP2024010026A patent/JP2024050700A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| UA126943C2 (en) | 2023-02-22 |
| US20190321440A1 (en) | 2019-10-24 |
| CR20200488A (en) | 2021-02-26 |
| KR20210005574A (en) | 2021-01-14 |
| JP2021522210A (en) | 2021-08-30 |
| PE20210855A1 (en) | 2021-05-18 |
| IL278053B1 (en) | 2024-01-01 |
| CA3089688A1 (en) | 2019-10-31 |
| MA52352A (en) | 2021-03-03 |
| EP3784262A1 (en) | 2021-03-03 |
| US11819532B2 (en) | 2023-11-21 |
| MX2020007633A (en) | 2020-09-14 |
| WO2019206853A1 (en) | 2019-10-31 |
| AR114290A1 (en) | 2020-08-12 |
| IL278053A (en) | 2020-11-30 |
| BR112020021729A2 (en) | 2021-01-26 |
| JP2024050700A (en) | 2024-04-10 |
| IL309537A (en) | 2024-02-01 |
| CN111886020B (en) | 2024-04-05 |
| PH12020551762A1 (en) | 2021-06-14 |
| TW201945386A (en) | 2019-12-01 |
| CL2020002695A1 (en) | 2021-02-19 |
| CN111886020A (en) | 2020-11-03 |
| US20240050516A1 (en) | 2024-02-15 |
| JP7460541B2 (en) | 2024-04-02 |
| AU2019260124A1 (en) | 2020-08-06 |
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