SG11202007172YA - Methods of treating subjects having diabetes with chronic kidney disease - Google Patents

Methods of treating subjects having diabetes with chronic kidney disease

Info

Publication number
SG11202007172YA
SG11202007172YA SG11202007172YA SG11202007172YA SG11202007172YA SG 11202007172Y A SG11202007172Y A SG 11202007172YA SG 11202007172Y A SG11202007172Y A SG 11202007172YA SG 11202007172Y A SG11202007172Y A SG 11202007172YA SG 11202007172Y A SG11202007172Y A SG 11202007172YA
Authority
SG
Singapore
Prior art keywords
diabetes
methods
kidney disease
chronic kidney
treating subjects
Prior art date
Application number
SG11202007172YA
Inventor
Bill Symonds
Steve Piscitelli
Karen Segal
Ruby Holder
Sophie Bozec
Sebastien Bolze
Pascale Fouqueray
Christophe Arbet-Engels
Julie Dubourg
Paul Strumph
Brandon Dale Swift
Margaret Smith Fletcher
Original Assignee
Metavant Sciences Gmbh
Poxel Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metavant Sciences Gmbh, Poxel Sa filed Critical Metavant Sciences Gmbh
Publication of SG11202007172YA publication Critical patent/SG11202007172YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
SG11202007172YA 2018-06-06 2019-06-06 Methods of treating subjects having diabetes with chronic kidney disease SG11202007172YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862681391P 2018-06-06 2018-06-06
PCT/US2019/035789 WO2019236844A1 (en) 2018-06-06 2019-06-06 Methods of treating subjects having diabetes with chronic kidney disease

Publications (1)

Publication Number Publication Date
SG11202007172YA true SG11202007172YA (en) 2020-08-28

Family

ID=67253960

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202007172YA SG11202007172YA (en) 2018-06-06 2019-06-06 Methods of treating subjects having diabetes with chronic kidney disease

Country Status (15)

Country Link
US (2) US11266652B2 (en)
EP (1) EP3801542B1 (en)
JP (1) JP2021529728A (en)
KR (1) KR20200130281A (en)
CN (1) CN111918655A (en)
AU (1) AU2019282727A1 (en)
BR (1) BR112020024643A2 (en)
CA (1) CA3102412A1 (en)
ES (1) ES2929994T3 (en)
IL (1) IL279174A (en)
MX (1) MX2020013210A (en)
PH (1) PH12020551159A1 (en)
SG (1) SG11202007172YA (en)
TW (1) TW202015696A (en)
WO (1) WO2019236844A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201924689A (en) 2017-10-02 2019-07-01 法商波瑟爾公司 Methods of treating heart failure with preserved ejection fraction
EP3801542B1 (en) 2018-06-06 2022-08-10 Poxel SA Methods of treating subjects having diabetes with chronic kidney disease
KR20210003786A (en) 2018-06-14 2021-01-12 폭셀 Film-coated tablet containing a triazine derivative for use in the treatment of diabetes
WO2021222231A1 (en) * 2020-04-27 2021-11-04 The Research Institute At Nationwide Children's Hospital PPARγ AGONISTS FOR TREATMENT OF KIDNEY DISEASE

Family Cites Families (28)

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US3287366A (en) 1963-12-24 1966-11-22 American Cyanamid Co Novel 1, 2-dihydro-s-triazines
JPS4864088A (en) 1971-12-13 1973-09-05
JPS5414986B2 (en) 1973-10-02 1979-06-11
IL136339A0 (en) 1997-12-12 2001-05-20 Abbott Lab Triazine angiogenesis inhibitors
FR2804113B1 (en) * 2000-01-26 2004-06-18 Lipha ANIMATED DIHYDRO-1,3,5-TRIAZINE DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS
FR2853650B1 (en) 2003-04-10 2006-07-07 Merck Sante Sas AMINE DEDOUBLING PROCESS USEFUL FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH INSULINO-RESISTANCE SYNDROME
WO2005070905A1 (en) 2004-01-20 2005-08-04 Merck & Co., Inc. Antidiabetic oxazolidinediones and thiazolidinediones
FR2896159B1 (en) 2006-01-13 2008-09-12 Merck Sante Soc Par Actions Si COMBINATION OF TRIAZINE DERIVATIVES AND INSULIN SENSITIZING AGENTS.
FR2896161B1 (en) 2006-01-13 2008-04-04 Merck Sante Soc Par Actions Si USE OF TRIAZINE DERIVATIVES FOR MANUFACTURING A MEDICAMENT HAVING A HEALING OR ANGIOGENIC EFFECT.
FR2896157B1 (en) 2006-01-13 2008-09-12 Merck Sante Soc Par Actions Si COMBINATION OF TRIAZINE DERIVATIVES AND INSULIN SECRETION STIMULATION AGENTS.
WO2008069222A1 (en) 2006-12-05 2008-06-12 Semiconductor Energy Laboratory Co., Ltd. Plasma display panel and field emission display
DE102007054416A1 (en) 2007-11-13 2009-05-14 Studiengesellschaft Kohle Mbh Process for the preparation of 3,6-dihydro-1,3,5-triazine derivatives for the treatment of diseases associated with insulin resistance syndrome
DE102008007314A1 (en) 2008-02-02 2009-08-06 Merck Patent Gmbh Process for the preparation of 3,6-dihydro-1,3,5-triazine derivatives
AU2009275963B2 (en) 2008-07-29 2014-07-10 Poxel Process of isolating enantiomer components from enantiomer mixtures by particle-size-controlled crystallization
WO2010066901A2 (en) 2008-12-12 2010-06-17 Poxel Tetrahydrotriazine compounds for treating diseases associated with ampk activity
ES2530223T3 (en) 2008-12-12 2015-02-27 Poxel S.A.S. Combination of insulin with triazine derivatives and their use to treat diabetes
WO2010109015A1 (en) 2009-03-26 2010-09-30 Poxel Process for enantiomeric separation of racemic dihydro-1,3,5 triazines via preferential crystallization
FR2948027A1 (en) 2009-07-17 2011-01-21 Merck Sante Sas DIHYDRO-1,3,5-TRIAZINE AMINO DERIVATIVES FOR THEIR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ISCHEMIA AND / OR REPERFUSION
TWI436768B (en) 2010-06-09 2014-05-11 Poxel Treatment of type 2 diabetes
ES2577930T3 (en) 2010-06-09 2016-07-19 Poxel Triazine derivatives to delay the onset of type 1 diabetes
PL2646422T3 (en) 2010-12-01 2015-12-31 Poxel Separation of triazine derivatives enantiomers using tartaric acid
US9211263B2 (en) * 2012-01-06 2015-12-15 Elcelyx Therapeutics, Inc. Compositions and methods of treating metabolic disorders
AU2013207329B2 (en) * 2012-01-06 2017-10-26 Anji Pharmaceuticals Inc. Compositions and methods for treating metabolic disorders
CA2812519A1 (en) * 2013-04-05 2014-10-05 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
WO2016077126A1 (en) 2014-11-10 2016-05-19 Merck Sharp & Dohme Corp. Sglt-2 inhibitors for treating metabolic disorders in patients with renal impairment or chronic kidney disease
CN105990398B (en) 2015-02-16 2019-01-11 上海和辉光电有限公司 Organic light emitting diode display and its manufacturing method
TW201924689A (en) 2017-10-02 2019-07-01 法商波瑟爾公司 Methods of treating heart failure with preserved ejection fraction
EP3801542B1 (en) 2018-06-06 2022-08-10 Poxel SA Methods of treating subjects having diabetes with chronic kidney disease

Also Published As

Publication number Publication date
CN111918655A (en) 2020-11-10
JP2021529728A (en) 2021-11-04
TW202015696A (en) 2020-05-01
US11266652B2 (en) 2022-03-08
US20200215072A1 (en) 2020-07-09
WO2019236844A1 (en) 2019-12-12
MX2020013210A (en) 2021-02-26
US20220387437A1 (en) 2022-12-08
PH12020551159A1 (en) 2021-06-07
CA3102412A1 (en) 2019-12-12
EP3801542A1 (en) 2021-04-14
IL279174A (en) 2021-01-31
AU2019282727A1 (en) 2020-11-26
KR20200130281A (en) 2020-11-18
ES2929994T3 (en) 2022-12-05
EP3801542B1 (en) 2022-08-10
BR112020024643A2 (en) 2021-03-02

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