SG11202006838VA - Process of making somatostatin modulators - Google Patents
Process of making somatostatin modulatorsInfo
- Publication number
- SG11202006838VA SG11202006838VA SG11202006838VA SG11202006838VA SG11202006838VA SG 11202006838V A SG11202006838V A SG 11202006838VA SG 11202006838V A SG11202006838V A SG 11202006838VA SG 11202006838V A SG11202006838V A SG 11202006838VA SG 11202006838V A SG11202006838V A SG 11202006838VA
- Authority
- SG
- Singapore
- Prior art keywords
- making
- somatostatin modulators
- modulators
- making somatostatin
- somatostatin
- Prior art date
Links
- 102000005157 Somatostatin Human genes 0.000 title 1
- 108010056088 Somatostatin Proteins 0.000 title 1
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title 1
- 229960000553 somatostatin Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Eye Examination Apparatus (AREA)
- Optical Communication System (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862618538P | 2018-01-17 | 2018-01-17 | |
| PCT/US2019/013844 WO2019143718A1 (en) | 2018-01-17 | 2019-01-16 | Process of making somatostatin modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202006838VA true SG11202006838VA (en) | 2020-08-28 |
Family
ID=67213594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202006838VA SG11202006838VA (en) | 2018-01-17 | 2019-01-16 | Process of making somatostatin modulators |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US10464918B2 (en) |
| EP (2) | EP4092018A1 (en) |
| JP (2) | JP7113900B2 (en) |
| KR (1) | KR102462586B1 (en) |
| CN (1) | CN111868049B (en) |
| AU (1) | AU2019209469B2 (en) |
| CA (1) | CA3088658A1 (en) |
| DK (1) | DK3740475T3 (en) |
| EA (1) | EA202091559A1 (en) |
| ES (1) | ES2923529T3 (en) |
| HR (1) | HRP20220852T1 (en) |
| HU (1) | HUE059184T2 (en) |
| IL (1) | IL276029B2 (en) |
| LT (1) | LT3740475T (en) |
| MA (1) | MA51625B1 (en) |
| MD (1) | MD3740475T2 (en) |
| MX (1) | MX2020007586A (en) |
| PL (1) | PL3740475T3 (en) |
| PT (1) | PT3740475T (en) |
| RS (1) | RS63387B1 (en) |
| SG (1) | SG11202006838VA (en) |
| SI (1) | SI3740475T1 (en) |
| TW (1) | TWI823891B (en) |
| UA (1) | UA127355C2 (en) |
| WO (1) | WO2019143718A1 (en) |
| ZA (1) | ZA202004497B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109715612B (en) | 2016-07-14 | 2022-09-16 | 克林提克斯医药股份有限公司 | Somatostatin modulators and uses thereof |
| WO2019023278A1 (en) | 2017-07-25 | 2019-01-31 | Crinetics Pharmaceuticals, Inc. | Somatostatin modulators and uses thereof |
| HRP20220852T1 (en) | 2018-01-17 | 2022-10-14 | Crinetics Pharmaceuticals, Inc. | Process of making somatostatin modulators |
| MX2023002761A (en) * | 2020-09-09 | 2023-04-03 | Crinetics Pharmaceuticals Inc | Formulations of a somatostatin modulator. |
| CN113214050B (en) * | 2021-05-15 | 2022-07-19 | 宁夏忠同生物科技有限公司 | Method for synthesizing 2,3,5, 6-tetrafluorophenol |
| IL314054A (en) * | 2022-01-11 | 2024-09-01 | Crinetics Pharmaceuticals Inc | Uses of a somatostatin modulator for the treatment of carcinoid syndrome |
| WO2023238112A1 (en) | 2022-06-10 | 2023-12-14 | Assia Chemical Industries Ltd. | Solid state forms of paltusotine and process for preparation thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1035154A (en) | 1910-05-16 | 1912-08-13 | Ernest G Clark | Machine for rectifying perforated music and masters. |
| US1046491A (en) | 1910-08-24 | 1912-12-10 | Alfred Randolph | Gas-engine. |
| FR2802206B1 (en) | 1999-12-14 | 2005-04-22 | Sod Conseils Rech Applic | 4-AMINOPIPERIDINE DERIVATIVES AND THEIR USE AS MEDICINAL PRODUCTS |
| WO2003045920A1 (en) | 2001-11-27 | 2003-06-05 | Merck & Co., Inc. | 4-aminoquinoline compounds |
| PL372295A1 (en) | 2002-02-04 | 2005-07-11 | F.Hoffmann-La Roche Ag | Quinoline derivatives as npy antagonists |
| WO2005024416A1 (en) | 2003-09-05 | 2005-03-17 | Binghe Wang | Water soluble boronic acid fluorescent reporter compounds and methods of use thereof |
| EP1773343A4 (en) | 2004-07-13 | 2009-05-13 | Glaxo Group Ltd | Antibacterial agents |
| AU2007309708A1 (en) | 2006-03-13 | 2008-05-02 | Merck Sharp & Dohme Corp. | Somatostatin agonists |
| GB0818241D0 (en) | 2008-10-06 | 2008-11-12 | Cancer Res Technology | Compounds and their use |
| CA2806332C (en) | 2010-07-30 | 2017-11-14 | Oncotherapy Science, Inc. | Quinoline derivatives and melk inhibitors containing the same |
| US9884828B2 (en) | 2011-05-23 | 2018-02-06 | Imago Pharmaceuticals, Inc. | Substituted cinnolines as inhibitors of LRRK2 kinase activity |
| US20140228417A1 (en) * | 2011-10-05 | 2014-08-14 | Mapi Pharma Ltd. | Process and intermediates for the preparation of substituted 2-arylthiazole carboxylic acids |
| EP2871179A4 (en) | 2012-07-03 | 2016-03-16 | Ono Pharmaceutical Co | Compound having agonistic activity on somatostatin receptor, and use thereof for medical purposes |
| AU2013331505A1 (en) | 2012-10-16 | 2015-04-30 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of ROR-gamma-t |
| CA2925651A1 (en) * | 2013-09-30 | 2015-04-02 | Ono Pharmaceutical Co., Ltd. | Compound having somatostatin receptor agonistic activity and pharmaceutical use thereof |
| TWI659021B (en) | 2013-10-10 | 2019-05-11 | 亞瑞克西斯製藥公司 | Inhibitors of kras g12c |
| US10011600B2 (en) | 2014-09-25 | 2018-07-03 | Araxes Pharma Llc | Methods and compositions for inhibition of Ras |
| WO2017003723A1 (en) | 2015-07-01 | 2017-01-05 | Crinetics Pharmaceuticals, Inc. | Somatostatin modulators and uses thereof |
| WO2017003724A1 (en) * | 2015-07-01 | 2017-01-05 | Crinetics Pharmaceuticals, Inc. | Somatostatin modulators and uses thereof |
| CN109715612B (en) | 2016-07-14 | 2022-09-16 | 克林提克斯医药股份有限公司 | Somatostatin modulators and uses thereof |
| HRP20220852T1 (en) | 2018-01-17 | 2022-10-14 | Crinetics Pharmaceuticals, Inc. | Process of making somatostatin modulators |
-
2019
- 2019-01-16 HR HRP20220852TT patent/HRP20220852T1/en unknown
- 2019-01-16 RS RS20220660A patent/RS63387B1/en unknown
- 2019-01-16 CA CA3088658A patent/CA3088658A1/en active Pending
- 2019-01-16 EP EP22168295.8A patent/EP4092018A1/en not_active Withdrawn
- 2019-01-16 SI SI201930277T patent/SI3740475T1/en unknown
- 2019-01-16 US US16/249,729 patent/US10464918B2/en active Active
- 2019-01-16 ES ES19740733T patent/ES2923529T3/en active Active
- 2019-01-16 JP JP2020538675A patent/JP7113900B2/en active Active
- 2019-01-16 PL PL19740733.1T patent/PL3740475T3/en unknown
- 2019-01-16 MA MA51625A patent/MA51625B1/en unknown
- 2019-01-16 KR KR1020207023546A patent/KR102462586B1/en active IP Right Grant
- 2019-01-16 EA EA202091559A patent/EA202091559A1/en unknown
- 2019-01-16 CN CN201980019970.7A patent/CN111868049B/en active Active
- 2019-01-16 PT PT197407331T patent/PT3740475T/en unknown
- 2019-01-16 DK DK19740733.1T patent/DK3740475T3/en active
- 2019-01-16 AU AU2019209469A patent/AU2019209469B2/en active Active
- 2019-01-16 MD MDE20201200T patent/MD3740475T2/en not_active IP Right Cessation
- 2019-01-16 EP EP19740733.1A patent/EP3740475B1/en active Active
- 2019-01-16 WO PCT/US2019/013844 patent/WO2019143718A1/en unknown
- 2019-01-16 IL IL276029A patent/IL276029B2/en unknown
- 2019-01-16 HU HUE19740733A patent/HUE059184T2/en unknown
- 2019-01-16 SG SG11202006838VA patent/SG11202006838VA/en unknown
- 2019-01-16 LT LTEPPCT/US2019/013844T patent/LT3740475T/en unknown
- 2019-01-16 UA UAA202004625A patent/UA127355C2/en unknown
- 2019-01-16 MX MX2020007586A patent/MX2020007586A/en unknown
- 2019-01-17 TW TW108101800A patent/TWI823891B/en active
- 2019-10-03 US US16/592,595 patent/US10889561B2/en active Active
-
2020
- 2020-07-21 ZA ZA2020/04497A patent/ZA202004497B/en unknown
- 2020-12-09 US US17/116,728 patent/US20210087165A1/en not_active Abandoned
-
2022
- 2022-07-26 JP JP2022118926A patent/JP2022166016A/en active Pending
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