SG11202006617RA - Combination therapies for the treatment of hepatocellular carcinoma - Google Patents

Combination therapies for the treatment of hepatocellular carcinoma

Info

Publication number
SG11202006617RA
SG11202006617RA SG11202006617RA SG11202006617RA SG11202006617RA SG 11202006617R A SG11202006617R A SG 11202006617RA SG 11202006617R A SG11202006617R A SG 11202006617RA SG 11202006617R A SG11202006617R A SG 11202006617RA SG 11202006617R A SG11202006617R A SG 11202006617RA
Authority
SG
Singapore
Prior art keywords
treatment
hepatocellular carcinoma
combination therapies
therapies
combination
Prior art date
Application number
SG11202006617RA
Inventor
Anand Selvaraj
Peter Smith
Original Assignee
Eisai R&D Man Co Ltd
Anand Selvaraj
Peter Smith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd, Anand Selvaraj, Peter Smith filed Critical Eisai R&D Man Co Ltd
Publication of SG11202006617RA publication Critical patent/SG11202006617RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
SG11202006617RA 2018-01-10 2019-01-09 Combination therapies for the treatment of hepatocellular carcinoma SG11202006617RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862615848P 2018-01-10 2018-01-10
PCT/US2019/012886 WO2019139977A1 (en) 2018-01-10 2019-01-09 Combination therapies for the treatment of hepatocellular carcinoma

Publications (1)

Publication Number Publication Date
SG11202006617RA true SG11202006617RA (en) 2020-08-28

Family

ID=65411938

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202006617RA SG11202006617RA (en) 2018-01-10 2019-01-09 Combination therapies for the treatment of hepatocellular carcinoma

Country Status (13)

Country Link
US (1) US11833119B2 (en)
EP (1) EP3737377A1 (en)
JP (2) JP7352569B2 (en)
KR (1) KR20200121302A (en)
CN (1) CN111787922A (en)
AU (1) AU2019206480A1 (en)
BR (1) BR112020014112A2 (en)
CA (1) CA3088292A1 (en)
IL (1) IL275981A (en)
MA (1) MA51570A (en)
MX (1) MX2020007375A (en)
SG (1) SG11202006617RA (en)
WO (1) WO2019139977A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117479958A (en) * 2022-05-30 2024-01-30 石药集团中奇制药技术(石家庄)有限公司 Pharmaceutical combination and pharmaceutical composition for the treatment of cancer

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60126997T2 (en) 2000-10-20 2007-10-25 Eisai R&D Management Co., Ltd. NITROGEN-CONTAINING AROMATIC RING COMPOUNDS FOR THE TREATMENT OF TUMORARY DISEASES
RS54033B1 (en) 2003-12-25 2015-10-30 Eisai R&D Management Co. Ltd. Crystal of salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)amino-phenoxy)-7-methoxy-6-quinolinecarboxamide or of solvate thereof and processes for producing these
RU2448708C3 (en) 2006-05-18 2017-09-28 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. ANTI-TUMOR MEANS AGAINST THYROID CANCER CANCER
JP5638244B2 (en) 2007-11-09 2014-12-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 Combination of angiogenesis inhibitors and antitumor platinum complexes
US20140378422A1 (en) 2012-01-31 2014-12-25 Novartis Ag Combination of a RTK inhibitor with an anti-estrogen and use thereof for the treatment of cancer
KR102265952B1 (en) 2013-06-26 2021-06-16 에자이 알앤드디 매니지먼트 가부시키가이샤 Use of eribulin and lenvatinib as combination therapy for treatment of cancer
CN105899490B (en) * 2013-10-18 2019-07-23 卫材R&D管理有限公司 Pyrimidine FGFR4 inhibitor
WO2015144808A1 (en) * 2014-03-26 2015-10-01 Astex Therapeutics Ltd Combinations of an fgfr inhibitor and an igf1r inhibitor
US20160089365A1 (en) * 2014-09-25 2016-03-31 Eisai R&D Management Co., Ltd. Immunostimulatory compound
US10562888B2 (en) 2015-04-14 2020-02-18 Eisai R&D Management Co., Ltd. Crystalline FGFR4 inhibitor compound and uses thereof
CN107304188A (en) * 2016-04-20 2017-10-31 成都融科博海科技有限公司 A kind of deuterated Kinase Selectivity inhibitor and its application
WO2017196854A1 (en) * 2016-05-10 2017-11-16 Eisai R&D Management Co., Ltd. Drug combinations for reducing cell viability and/or cell proliferation

Also Published As

Publication number Publication date
AU2019206480A1 (en) 2020-08-27
WO2019139977A1 (en) 2019-07-18
RU2020126673A3 (en) 2022-04-19
IL275981A (en) 2020-08-31
RU2020126673A (en) 2022-02-10
CA3088292A1 (en) 2019-07-18
JP7352569B2 (en) 2023-09-28
MA51570A (en) 2020-11-18
EP3737377A1 (en) 2020-11-18
US11833119B2 (en) 2023-12-05
JP2023175825A (en) 2023-12-12
KR20200121302A (en) 2020-10-23
JP2021512140A (en) 2021-05-13
MX2020007375A (en) 2020-11-09
US20200360371A1 (en) 2020-11-19
BR112020014112A2 (en) 2020-12-01
CN111787922A (en) 2020-10-16

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