SG11202005978RA - Method for preparing tolimidone on large scale - Google Patents

Method for preparing tolimidone on large scale

Info

Publication number
SG11202005978RA
SG11202005978RA SG11202005978RA SG11202005978RA SG11202005978RA SG 11202005978R A SG11202005978R A SG 11202005978RA SG 11202005978R A SG11202005978R A SG 11202005978RA SG 11202005978R A SG11202005978R A SG 11202005978RA SG 11202005978R A SG11202005978R A SG 11202005978RA
Authority
SG
Singapore
Prior art keywords
large scale
tolimidone
preparing
preparing tolimidone
scale
Prior art date
Application number
SG11202005978RA
Inventor
Kwang Ok Lee
Kyung Hwa Lee
Eun Ju Jeong
Original Assignee
Bukwang Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bukwang Pharmaceutical Co Ltd filed Critical Bukwang Pharmaceutical Co Ltd
Publication of SG11202005978RA publication Critical patent/SG11202005978RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SG11202005978RA 2018-01-11 2018-01-11 Method for preparing tolimidone on large scale SG11202005978RA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2018/000530 WO2019139185A1 (en) 2018-01-11 2018-01-11 Method for preparing tolimidone on large scale

Publications (1)

Publication Number Publication Date
SG11202005978RA true SG11202005978RA (en) 2020-07-29

Family

ID=67219718

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202005978RA SG11202005978RA (en) 2018-01-11 2018-01-11 Method for preparing tolimidone on large scale

Country Status (12)

Country Link
US (1) US11254645B2 (en)
EP (1) EP3737669B1 (en)
JP (1) JP7033662B2 (en)
CN (1) CN111587245B (en)
AU (1) AU2018401298B2 (en)
BR (1) BR112020013924A2 (en)
CA (1) CA3087085A1 (en)
IL (1) IL275869B1 (en)
MX (1) MX2020007006A (en)
SG (1) SG11202005978RA (en)
WO (1) WO2019139185A1 (en)
ZA (1) ZA202004851B (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3922345A (en) * 1971-10-29 1975-11-25 Pfizer Pyrimidinones and hydroxy pyrimidines
RU2646475C2 (en) * 2011-12-12 2018-03-05 МЕЛИОР ФАРМАСЬЮТИКАЛЗ Ай, ИНК. Treatment of type i and ii diabetes
KR20160065496A (en) * 2014-12-01 2016-06-09 부광약품 주식회사 Recrystallization method for purification of phenoxy-2(1h)-pyrimidinone analogues
KR101827744B1 (en) * 2016-10-31 2018-02-09 부광약품 주식회사 Method for preparing tolimidone on large scale

Also Published As

Publication number Publication date
CA3087085A1 (en) 2019-07-18
WO2019139185A1 (en) 2019-07-18
EP3737669A4 (en) 2021-09-15
AU2018401298B2 (en) 2024-04-04
AU2018401298A1 (en) 2020-07-16
EP3737669B1 (en) 2023-08-30
CN111587245B (en) 2023-10-31
IL275869B1 (en) 2024-04-01
EP3737669A1 (en) 2020-11-18
JP2021513506A (en) 2021-05-27
US11254645B2 (en) 2022-02-22
JP7033662B2 (en) 2022-03-10
EP3737669C0 (en) 2023-08-30
BR112020013924A2 (en) 2020-12-01
IL275869A (en) 2020-08-31
MX2020007006A (en) 2022-10-03
CN111587245A (en) 2020-08-25
ZA202004851B (en) 2022-04-28
US20210061772A1 (en) 2021-03-04

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