SG11202004653TA - Novel bradykinin b2 receptor antagonists - Google Patents
Novel bradykinin b2 receptor antagonistsInfo
- Publication number
- SG11202004653TA SG11202004653TA SG11202004653TA SG11202004653TA SG11202004653TA SG 11202004653T A SG11202004653T A SG 11202004653TA SG 11202004653T A SG11202004653T A SG 11202004653TA SG 11202004653T A SG11202004653T A SG 11202004653TA SG 11202004653T A SG11202004653T A SG 11202004653TA
- Authority
- SG
- Singapore
- Prior art keywords
- receptor antagonists
- novel bradykinin
- bradykinin
- novel
- antagonists
- Prior art date
Links
- 229940123765 Bradykinin B2 receptor antagonist Drugs 0.000 title 1
- 239000003359 bradykinin B2 receptor antagonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17203675 | 2017-11-24 | ||
| PCT/EP2018/082338 WO2019101906A1 (en) | 2017-11-24 | 2018-11-23 | Novel bradykinin b2 receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202004653TA true SG11202004653TA (en) | 2020-06-29 |
Family
ID=60473364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202004653TA SG11202004653TA (en) | 2017-11-24 | 2018-11-23 | Novel bradykinin b2 receptor antagonists |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US10836748B2 (en) |
| EP (2) | EP3998259A1 (en) |
| JP (2) | JP7164619B2 (en) |
| KR (1) | KR102413321B1 (en) |
| CN (1) | CN111433196B (en) |
| AR (1) | AR113839A1 (en) |
| AU (1) | AU2018371186B2 (en) |
| BR (1) | BR112020010298A2 (en) |
| CA (1) | CA3082948A1 (en) |
| CY (1) | CY1125348T1 (en) |
| DK (1) | DK3713928T3 (en) |
| EA (1) | EA202091256A1 (en) |
| ES (1) | ES2908409T3 (en) |
| HR (1) | HRP20220429T1 (en) |
| HU (1) | HUE058217T2 (en) |
| IL (1) | IL274883B2 (en) |
| LT (1) | LT3713928T (en) |
| MA (1) | MA50804B1 (en) |
| MX (1) | MX2020005287A (en) |
| PH (1) | PH12020550683A1 (en) |
| PL (1) | PL3713928T3 (en) |
| PT (1) | PT3713928T (en) |
| RS (1) | RS63087B1 (en) |
| SG (1) | SG11202004653TA (en) |
| SI (1) | SI3713928T1 (en) |
| SM (1) | SMT202200154T1 (en) |
| TW (1) | TWI768156B (en) |
| UY (1) | UY37981A (en) |
| WO (1) | WO2019101906A1 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3713928T (en) | 2017-11-24 | 2022-03-08 | Pharvaris Netherlands B V | Novel bradykinin b2 receptor antagonists |
| UY38706A (en) | 2019-05-23 | 2020-12-31 | Pharvaris Gmbh | CYCLIC ANTAGONISTS OF BRADIQUININ B2 RECEPTOR |
| UY38707A (en) * | 2019-05-23 | 2020-12-31 | Pharvaris Gmbh | NEW CYCLIC ANTAGONISTS OF BRADIQUININ B2 RECEPTOR |
| JP2023549849A (en) | 2020-11-12 | 2023-11-29 | ファルバリス ゲーエムベーハー | Prevention and treatment of angioedema |
| DK4203919T3 (en) | 2021-08-05 | 2024-04-29 | Pharvaris Gmbh | LIPID BASED COMPOSITION FOR ORAL ADMINISTRATION OF BRADYKININ B2 RECEPTOR ANTAGONISTS |
| WO2023012324A1 (en) | 2021-08-05 | 2023-02-09 | Pharvaris Gmbh | Solid form of a bradykinin b2-receptor antagonist |
| KR20240161689A (en) | 2022-03-25 | 2024-11-12 | 파르바리스 게엠베하 | Solid composition comprising a solubilized bradykinin B2 receptor antagonist |
| TW202345810A (en) | 2022-03-25 | 2023-12-01 | 瑞士商帕法瑞斯有限責任公司 | Solid extended-release composition comprising bradykinin b2-receptor antagonists |
| WO2023180577A1 (en) | 2022-03-25 | 2023-09-28 | Pharvaris Gmbh | Therapeutic uses of bradykinin b2-receptor antagonists |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU680870B2 (en) | 1993-04-28 | 1997-08-14 | Astellas Pharma Inc. | New heterocyclic compounds |
| CA2203659A1 (en) | 1994-10-27 | 1996-05-09 | Teruo Oku | Pyridopyrimidones, quinolines and fused n-heterocycles as bradykinin antagonists |
| FR2737892B1 (en) | 1995-08-17 | 1997-10-24 | Fournier Ind & Sante | NOVEL BENZENESULFONAMIDE COMPOUNDS, PREPARATION METHOD AND THERAPEUTIC USE |
| GB9602029D0 (en) | 1996-02-01 | 1996-04-03 | Fujisawa Pharmaceutical Co | New heterocyclic compounds |
| DE19609827A1 (en) | 1996-03-13 | 1997-09-18 | Hoechst Ag | Aminoalkyl and acylaminoalkyl ethers, processes for their preparation and their use as bradykinin receptor antagonists |
| DE19610784A1 (en) | 1996-03-19 | 1997-09-25 | Hoechst Ag | Fluoroalkyl and fluoroalkoxy-substituted heterocyclic bradykinin antagonists, processes for their preparation and their use |
| DE19612067A1 (en) | 1996-03-27 | 1997-10-02 | Hoechst Ag | Use of bradykinin antagonists for the manufacture of medicaments for the treatment of chronic fibrogenetic liver diseases and acute liver diseases |
| AUPN952696A0 (en) | 1996-04-29 | 1996-05-23 | Fujisawa Pharmaceutical Co., Ltd. | New heterocyclic compounds |
| DE19712960A1 (en) | 1997-03-27 | 1998-10-01 | Hoechst Ag | Benzyloxy-substituted, fused N-heterocycles, processes for their preparation and their use as bradykinin receptor antagonists |
| JP2002517461A (en) | 1998-06-08 | 2002-06-18 | アドバンスド メディスン インコーポレーテッド | Bradykinin antagonist |
| JP3353784B2 (en) | 1998-10-21 | 2002-12-03 | 藤沢薬品工業株式会社 | Glass body of known bradykinin antagonist |
| FR2790260B1 (en) | 1999-02-26 | 2001-05-04 | Fournier Ind & Sante | NOVEL N- (BENZENESULFONAMIDE) COMPOUNDS, METHOD OF PREPARATION AND THERAPEUTIC USE |
| GB9913079D0 (en) | 1999-06-04 | 1999-08-04 | Novartis Ag | Organic compounds |
| WO2001056995A1 (en) | 2000-01-18 | 2001-08-09 | Nuerogen Corporation | Substituted imidazoles as selective modulators of bradykinin b2 receptors |
| CA2364178C (en) | 2000-12-05 | 2006-01-10 | Yasuhiro Katsu | N-benzenesulfonyl l-proline compounds as bradykinin antagonists |
| WO2003087090A2 (en) | 2002-04-10 | 2003-10-23 | Ortho-Mcneil Pharmaceutical,Inc. | Novel heteroaryl alkylamide derivatives useful as bradykinin receptor modulators |
| ITMI20021247A1 (en) | 2002-06-07 | 2003-12-09 | Menarini Ricerche Spa | NON-PEPTID BASIC ANTAGONISTS OF BRADICHININE AND THEIR USE PHARMACEUTICAL INFORMATION |
| ITMI20041963A1 (en) | 2004-10-15 | 2005-01-15 | Luso Farmaco Inst | "NON-PEPTIDIAL ANTAGONISTS OF BRADICHININ AND THEIR PHARMACEUTICAL COMPOSITIONS" |
| EP1741444A1 (en) | 2005-07-05 | 2007-01-10 | Jerini AG | Kinin antagonists for treating bladder dysfunction |
| TWI407960B (en) * | 2007-03-23 | 2013-09-11 | Jerini Ag | Small molecule bradykinin b2 receptor modulators |
| AR073304A1 (en) * | 2008-09-22 | 2010-10-28 | Jerini Ag | MODULATORS OF THE BRADIQUININE B2 RECEPTOR OF SMALL MOLECULA |
| RU2015138443A (en) | 2013-03-14 | 2017-04-20 | Шир Хьюман Дженетик Терапис, Инк. | METHODS FOR TREATMENT OF ANGIONEUROTIC Edema Mediated by Bradykinin B2 Receptors |
| PT3713928T (en) | 2017-11-24 | 2022-03-08 | Pharvaris Netherlands B V | Novel bradykinin b2 receptor antagonists |
-
2018
- 2018-11-23 PT PT188189922T patent/PT3713928T/en unknown
- 2018-11-23 BR BR112020010298-9A patent/BR112020010298A2/en unknown
- 2018-11-23 DK DK18818992.2T patent/DK3713928T3/en active
- 2018-11-23 IL IL274883A patent/IL274883B2/en unknown
- 2018-11-23 AR ARP180103444A patent/AR113839A1/en unknown
- 2018-11-23 LT LTEPPCT/EP2018/082338T patent/LT3713928T/en unknown
- 2018-11-23 UY UY0001037981A patent/UY37981A/en active IP Right Grant
- 2018-11-23 PL PL18818992T patent/PL3713928T3/en unknown
- 2018-11-23 SI SI201830628T patent/SI3713928T1/en unknown
- 2018-11-23 EA EA202091256A patent/EA202091256A1/en unknown
- 2018-11-23 EP EP21213719.4A patent/EP3998259A1/en active Pending
- 2018-11-23 JP JP2020545875A patent/JP7164619B2/en active Active
- 2018-11-23 TW TW107141872A patent/TWI768156B/en active
- 2018-11-23 HR HRP20220429TT patent/HRP20220429T1/en unknown
- 2018-11-23 SM SM20220154T patent/SMT202200154T1/en unknown
- 2018-11-23 CA CA3082948A patent/CA3082948A1/en active Pending
- 2018-11-23 AU AU2018371186A patent/AU2018371186B2/en active Active
- 2018-11-23 EP EP18818992.2A patent/EP3713928B1/en active Active
- 2018-11-23 MX MX2020005287A patent/MX2020005287A/en unknown
- 2018-11-23 SG SG11202004653TA patent/SG11202004653TA/en unknown
- 2018-11-23 CN CN201880076162.XA patent/CN111433196B/en active Active
- 2018-11-23 ES ES18818992T patent/ES2908409T3/en active Active
- 2018-11-23 HU HUE18818992A patent/HUE058217T2/en unknown
- 2018-11-23 WO PCT/EP2018/082338 patent/WO2019101906A1/en active IP Right Grant
- 2018-11-23 MA MA50804A patent/MA50804B1/en unknown
- 2018-11-23 KR KR1020207017972A patent/KR102413321B1/en active Active
- 2018-11-23 RS RS20220335A patent/RS63087B1/en unknown
-
2020
- 2020-04-28 US US16/861,131 patent/US10836748B2/en active Active
- 2020-05-21 PH PH12020550683A patent/PH12020550683A1/en unknown
- 2020-09-25 US US17/033,347 patent/US11261173B2/en active Active
-
2022
- 2022-01-18 US US17/578,161 patent/US11820756B2/en active Active
- 2022-04-11 CY CY20221100272T patent/CY1125348T1/en unknown
- 2022-10-20 JP JP2022168473A patent/JP2023002701A/en active Pending
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