SG11202003984UA - Novel sulfonamide carboxamide compounds - Google Patents

Novel sulfonamide carboxamide compounds

Info

Publication number
SG11202003984UA
SG11202003984UA SG11202003984UA SG11202003984UA SG11202003984UA SG 11202003984U A SG11202003984U A SG 11202003984UA SG 11202003984U A SG11202003984U A SG 11202003984UA SG 11202003984U A SG11202003984U A SG 11202003984UA SG 11202003984U A SG11202003984U A SG 11202003984UA
Authority
SG
Singapore
Prior art keywords
carboxamide compounds
novel sulfonamide
sulfonamide carboxamide
novel
compounds
Prior art date
Application number
SG11202003984UA
Inventor
Matthew Cooper
David Miller
Angus Macleod
Stephen Thom
Stephen St-Gallay
Jonathan Shannon
Ian Strutt
Original Assignee
Inflazome Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1718563.8A external-priority patent/GB201718563D0/en
Priority claimed from GBGB1721727.4A external-priority patent/GB201721727D0/en
Priority claimed from GBGB1721726.6A external-priority patent/GB201721726D0/en
Priority claimed from GBGB1810983.5A external-priority patent/GB201810983D0/en
Priority claimed from GBGB1813281.1A external-priority patent/GB201813281D0/en
Application filed by Inflazome Ltd filed Critical Inflazome Ltd
Publication of SG11202003984UA publication Critical patent/SG11202003984UA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11202003984UA 2017-11-09 2018-11-09 Novel sulfonamide carboxamide compounds SG11202003984UA (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GBGB1718563.8A GB201718563D0 (en) 2017-11-09 2017-11-09 Novel compounds
GBGB1721727.4A GB201721727D0 (en) 2017-12-22 2017-12-22 Novel compounds
GBGB1721726.6A GB201721726D0 (en) 2017-12-22 2017-12-22 Novel compounds
GBGB1810983.5A GB201810983D0 (en) 2018-07-04 2018-07-04 Novel compounds
GBGB1813281.1A GB201813281D0 (en) 2018-08-15 2018-08-15 Novel compounds
PCT/EP2018/080737 WO2019092170A1 (en) 2017-11-09 2018-11-09 Novel sulfonamide carboxamide compounds

Publications (1)

Publication Number Publication Date
SG11202003984UA true SG11202003984UA (en) 2020-05-28

Family

ID=64456934

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202003984UA SG11202003984UA (en) 2017-11-09 2018-11-09 Novel sulfonamide carboxamide compounds

Country Status (16)

Country Link
US (1) US20200317637A1 (en)
EP (1) EP3707134A1 (en)
JP (1) JP2021502364A (en)
KR (1) KR20200087759A (en)
CN (1) CN111315733A (en)
AU (1) AU2018363771A1 (en)
BR (1) BR112020008981A2 (en)
CA (1) CA3078195A1 (en)
CL (1) CL2020001212A1 (en)
IL (1) IL273786A (en)
MA (1) MA50567A (en)
MX (1) MX2020004423A (en)
PE (1) PE20210050A1 (en)
RU (1) RU2020115098A (en)
SG (1) SG11202003984UA (en)
WO (1) WO2019092170A1 (en)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018210525B2 (en) 2017-01-23 2022-06-02 Genentech, Inc. Chemical compounds as inhibitors of interleukin-1 activity
BR112019024831A2 (en) 2017-05-24 2020-06-09 The University Of Queensland compound, salt, solvate or prodrug, pharmaceutical composition, method of treating or preventing a disease, method of inhibiting nlrp3
US11370776B2 (en) 2017-07-07 2022-06-28 Inflazome Limited Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors
TW201910316A (en) 2017-08-15 2019-03-16 愛爾蘭商英弗雷佐姆有限公司 Novel compound
US11773058B2 (en) 2017-08-15 2023-10-03 Inflazome Limited Sulfonamide carboxamide compounds
US11518739B2 (en) 2017-08-15 2022-12-06 Inflazome Limited Sulfonamide carboxamide compounds
US11542255B2 (en) 2017-08-15 2023-01-03 Inflazome Limited Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors
EP3668843A1 (en) 2017-08-15 2020-06-24 Inflazome Limited Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors
WO2019166628A1 (en) 2018-03-02 2019-09-06 Inflazome Limited Novel compounds
WO2019166627A1 (en) 2018-03-02 2019-09-06 Inflazome Limited Novel compounds
US11905252B2 (en) 2018-03-02 2024-02-20 Inflazome Limited Compounds
EP3759103A1 (en) 2018-03-02 2021-01-06 Inflazome Limited Novel compounds
CN112437683A (en) 2018-07-20 2021-03-02 豪夫迈·罗氏有限公司 Sulfonylurea compounds useful as inhibitors of interleukin-1 activity
GB201902327D0 (en) 2019-02-20 2019-04-03 Inflazome Ltd Novel compounds
BR112021002770A2 (en) 2018-08-15 2021-05-04 Inflazome Limited innovative sulfonamideurea compounds
GB201819083D0 (en) 2018-11-23 2019-01-09 Inflazome Ltd Novel compounds
GB201905265D0 (en) 2019-04-12 2019-05-29 Inflazome Ltd Inflammasome inhibition
AR119731A1 (en) * 2019-05-17 2022-01-05 Novartis Ag NLRP3 INFLAMASOME INHIBITORS
CN114008030A (en) 2019-06-21 2022-02-01 Ac免疫有限公司 Fused 1, 2-thiazoles and 1, 2-thiazines as NLRP3 modulators
CN114401971A (en) 2019-08-16 2022-04-26 英夫拉索姆有限公司 Macrocyclic sulfonylurea derivatives as NLRP3 inhibitors
JP2022547882A (en) 2019-09-06 2022-11-16 インフレイゾーム リミテッド NLRP3 inhibitor
EP4107153A1 (en) 2020-02-18 2022-12-28 Inflazome Limited Compounds
MX2022013984A (en) 2020-05-08 2023-01-30 Halia Therapeutics Inc Inhibitors of nek7 kinase.
TW202208368A (en) 2020-06-08 2022-03-01 美商哈利亞製藥公司 Inhibitors of nek7 kinase
WO2021255279A1 (en) 2020-06-19 2021-12-23 Ac Immune Sa D i h yd rooxazo le and thiourea derivatives modulating the nlrp3 inflammasome pathway
JP7196363B2 (en) * 2020-11-05 2022-12-26 出光興産株式会社 Compounds, materials for organic electroluminescence devices, organic electroluminescence devices and electronic devices
CN114516878B (en) * 2020-11-20 2024-02-02 上海拓界生物医药科技有限公司 Tricyclic compounds and medical uses thereof
CN117279903A (en) * 2021-02-10 2023-12-22 杭州英创医药科技有限公司 Compounds as NLRP3 inhibitors
EP4363406A1 (en) * 2021-07-02 2024-05-08 Astrazeneca AB Nlrp3 inflammasome inhibitors
IL311784A (en) * 2021-09-29 2024-05-01 Viva Star Biosciences Suzhou Co Ltd Substituted sulfonylurea compounds as inhibitors of interleukin-1 activity
WO2023055427A1 (en) * 2021-09-29 2023-04-06 New York Blood Center, Inc. Small molecule antagonists of pf4
WO2023118521A1 (en) 2021-12-22 2023-06-29 Ac Immune Sa Dihydro-oxazol derivative compounds
WO2023158824A1 (en) * 2022-02-21 2023-08-24 Viva Star Biosciences (Suzhou) Co., Ltd. Novel bicyclic substituted sulfonylurea compounds as inhibitors of interleukin- 1 activity
US20240034735A1 (en) 2022-07-14 2024-02-01 Ac Immune Sa Novel compounds
US20240101563A1 (en) 2022-07-28 2024-03-28 Ac Immune Sa Novel compounds
US20240158394A1 (en) 2022-09-14 2024-05-16 Halia Therapeutics, Inc. Nek7 inhibitors

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045573A (en) * 1983-08-22 1985-03-12 Nissan Chem Ind Ltd Pyrazolesulfonylurea derivative, its preparation and selective herbicide containing said derivative
AU578307B2 (en) * 1984-09-17 1988-10-20 E.I. Du Pont De Nemours And Company Herbicidal pyrazolesulfonamides
FI855180A (en) * 1985-01-18 1986-07-19 Nissan Chemical Ind Ltd PYRAZOLESULFONAMIDDERIVAT, FOERFARANDE FOER DESS FRAMSTAELLANDE OCH DET INNEHAOLLANDE OGRAESGIFT.
US4802908A (en) * 1987-01-22 1989-02-07 E. I. Du Pont De Nemours And Company Herbicidal 2-(1H)-pyrazinones
CA2369967A1 (en) * 2001-02-12 2002-08-12 Joseph Anthony Cornicelli Methods of treating nuclear factor-kappa b mediated diseases and disorders
AR052900A1 (en) * 2005-02-11 2007-04-11 Astrazeneca Ab DERIVATIVES OF TIAZOL, A METHOD FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THEIR USE IN THE PREPARATION OF MEDICINES FOR THE TREATMENT OF DISEASES MEDIATED BY ECE-1
JP5688404B2 (en) * 2010-03-05 2015-03-25 協和発酵キリン株式会社 Pyrazolopyrimidine derivatives
CA2975192A1 (en) * 2015-02-16 2016-08-25 The University Of Queensland Sulfonylureas and related compounds and use of same
EP3872070A1 (en) * 2016-04-18 2021-09-01 Novartis AG Compounds and compositions for treating conditions associated with nlrp activity
AU2018210525B2 (en) * 2017-01-23 2022-06-02 Genentech, Inc. Chemical compounds as inhibitors of interleukin-1 activity
BR112019024831A2 (en) * 2017-05-24 2020-06-09 The University Of Queensland compound, salt, solvate or prodrug, pharmaceutical composition, method of treating or preventing a disease, method of inhibiting nlrp3
KR20200041918A (en) * 2017-08-15 2020-04-22 인플라좀 리미티드 Novel sulfonamide carboxamide compounds
TW201910316A (en) * 2017-08-15 2019-03-16 愛爾蘭商英弗雷佐姆有限公司 Novel compound
EP3668843A1 (en) * 2017-08-15 2020-06-24 Inflazome Limited Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors
US11542255B2 (en) * 2017-08-15 2023-01-03 Inflazome Limited Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors
EP3668862A1 (en) * 2017-08-15 2020-06-24 Inflazome Limited Novel sulfonamide carboxamide compounds
EP3707137A1 (en) * 2017-11-09 2020-09-16 Inflazome Limited Novel sulfonamide carboxamide compounds

Also Published As

Publication number Publication date
EP3707134A1 (en) 2020-09-16
BR112020008981A2 (en) 2020-11-17
RU2020115098A (en) 2021-12-10
CA3078195A1 (en) 2019-05-16
RU2020115098A3 (en) 2022-04-22
AU2018363771A1 (en) 2020-05-14
MA50567A (en) 2020-09-16
JP2021502364A (en) 2021-01-28
US20200317637A1 (en) 2020-10-08
CN111315733A (en) 2020-06-19
IL273786A (en) 2020-05-31
PE20210050A1 (en) 2021-01-08
MX2020004423A (en) 2020-08-06
WO2019092170A1 (en) 2019-05-16
KR20200087759A (en) 2020-07-21
CL2020001212A1 (en) 2020-10-30

Similar Documents

Publication Publication Date Title
IL272555A (en) Novel sulfonamide carboxamide compounds
IL273786A (en) Novel sulfonamide carboxamide compounds
IL271716A (en) Novel sulfonamide carboxamide compounds
IL272550A (en) Novel sulfonamide carboxamide compounds
ZA201900609B (en) Sulfonamides as gpr40- and gpr120-agonists
RS62708B1 (en) Novel compounds
GB201720187D0 (en) Novel Compounds
GB201702947D0 (en) Novel compounds
GB201721727D0 (en) Novel compounds
GB201718561D0 (en) Novel compounds
GB201718563D0 (en) Novel compounds
GB201718565D0 (en) Novel compounds
GB201716131D0 (en) Novel compounds
GB201714699D0 (en) Novel compounds
GB201713083D0 (en) Novel compounds
GB201713085D0 (en) Novel compounds
GB201713082D0 (en) Novel compounds
GB201713079D0 (en) Novel Compounds
GB201713076D0 (en) Novel compounds
GB201711682D0 (en) Novel compounds
GB201711549D0 (en) Novel compounds
GB201710942D0 (en) Novel compounds
GB201710331D0 (en) Novel compounds
GB201709919D0 (en) Novel compounds
GB201709824D0 (en) Novel Compounds