SG11202003949TA - Method for inactivating zika virus and for determining the completeness of inactivation - Google Patents
Method for inactivating zika virus and for determining the completeness of inactivationInfo
- Publication number
- SG11202003949TA SG11202003949TA SG11202003949TA SG11202003949TA SG11202003949TA SG 11202003949T A SG11202003949T A SG 11202003949TA SG 11202003949T A SG11202003949T A SG 11202003949TA SG 11202003949T A SG11202003949T A SG 11202003949TA SG 11202003949T A SG11202003949T A SG 11202003949TA
- Authority
- SG
- Singapore
- Prior art keywords
- completeness
- inactivation
- determining
- zika virus
- inactivating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24071—Demonstrated in vivo effect
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24151—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24161—Methods of inactivation or attenuation
- C12N2770/24163—Methods of inactivation or attenuation by chemical treatment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24161—Methods of inactivation or attenuation
- C12N2770/24164—Methods of inactivation or attenuation by serial passage
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762581500P | 2017-11-03 | 2017-11-03 | |
US201762592995P | 2017-11-30 | 2017-11-30 | |
PCT/US2018/059227 WO2019090233A2 (en) | 2017-11-03 | 2018-11-05 | Method for inactivating zika virus and for determining the completeness of inactivation |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202003949TA true SG11202003949TA (en) | 2020-05-28 |
Family
ID=64427224
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202003796XA SG11202003796XA (en) | 2017-11-03 | 2018-11-05 | Zika vaccines and immunogenic compositions, and methods of using the same |
SG11202003800YA SG11202003800YA (en) | 2017-11-03 | 2018-11-05 | Zika vaccines and immunogenic compositions, and methods of using the same |
SG11202003949TA SG11202003949TA (en) | 2017-11-03 | 2018-11-05 | Method for inactivating zika virus and for determining the completeness of inactivation |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202003796XA SG11202003796XA (en) | 2017-11-03 | 2018-11-05 | Zika vaccines and immunogenic compositions, and methods of using the same |
SG11202003800YA SG11202003800YA (en) | 2017-11-03 | 2018-11-05 | Zika vaccines and immunogenic compositions, and methods of using the same |
Country Status (12)
Country | Link |
---|---|
US (4) | US11648304B2 (en) |
EP (3) | EP3703739A2 (en) |
JP (4) | JP7443232B2 (en) |
KR (3) | KR20200117981A (en) |
CN (3) | CN111615397A (en) |
AU (6) | AU2018359556B2 (en) |
BR (3) | BR112020008693A2 (en) |
CA (3) | CA3081586A1 (en) |
MX (3) | MX2020004367A (en) |
MY (2) | MY194449A (en) |
SG (3) | SG11202003796XA (en) |
WO (3) | WO2019090228A2 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111615397A (en) | 2017-11-03 | 2020-09-01 | 武田疫苗股份有限公司 | Zika vaccine and immunogenic compositions and methods of use thereof |
BR112020009960A2 (en) * | 2017-11-30 | 2020-11-10 | Takeda Vaccines, Inc. | method for inactivating Zika virus and related methods |
US20220211836A1 (en) * | 2019-05-08 | 2022-07-07 | Takeda Vaccines, Inc. | Inactivated virus compositions and zika vaccine formulations |
WO2021236845A1 (en) | 2020-05-20 | 2021-11-25 | Takeda Vaccines, Inc. | Method for detection of zika virus specific antibodies |
WO2022076865A1 (en) | 2020-10-09 | 2022-04-14 | Takeda Vaccines, Inc. | Methods for determining complement-fixing antibodies |
CN112980805B (en) * | 2021-02-25 | 2022-11-08 | 中国科学院广州生物医药与健康研究院 | Recombinant Zika virus attenuated strain and preparation method and application thereof |
CN112941201B (en) * | 2021-03-01 | 2022-03-08 | 武汉珈创生物技术股份有限公司 | Mixed primer for multi-cell species identification and cross contamination detection and use method thereof |
WO2023154043A1 (en) | 2022-02-09 | 2023-08-17 | Takeda Vaccines, Inc. | Zika vaccines and immunogenic compositions, and methods of using the same |
KR102619184B1 (en) * | 2022-12-27 | 2023-12-29 | 주식회사 그린백스 | Vaccine composition comprising Zika virus inactivated by Epigallocatechin-3-gallate as an active ingredient |
Family Cites Families (107)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3238190A (en) | 1963-10-23 | 1966-03-01 | Madaus & Co K G Fa Dr | Aescin recovery |
US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
CA1331443C (en) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
US5278302A (en) | 1988-05-26 | 1994-01-11 | University Patents, Inc. | Polynucleotide phosphorodithioates |
DK0382271T3 (en) | 1989-02-04 | 1995-05-01 | Akzo Nobel Nv | Tocoler as adjuvants in vaccines |
HU212924B (en) | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
FR2649012B1 (en) | 1989-07-03 | 1991-10-25 | Seppic Sa | INJECTABLE MULTIPHASIC EMULSIONS |
FR2649013B1 (en) | 1989-07-03 | 1991-10-25 | Seppic Sa | VACCINES AND VECTORS OF FLUID ACTIVE INGREDIENTS CONTAINING METABOLIZABLE OIL |
EP0468520A3 (en) | 1990-07-27 | 1992-07-01 | Mitsui Toatsu Chemicals, Inc. | Immunostimulatory remedies containing palindromic dna sequences |
JP4028593B2 (en) | 1993-03-23 | 2007-12-26 | グラクソスミスクライン・バイオロジカルス・ソシエテ・アノニム | 3-O deacylated monophosphoryl lipid A-containing vaccine composition |
GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
WO1995026204A1 (en) | 1994-03-25 | 1995-10-05 | Isis Pharmaceuticals, Inc. | Immune stimulation by phosphorothioate oligonucleotide analogs |
EP1167379A3 (en) | 1994-07-15 | 2004-09-08 | University Of Iowa Research Foundation | Immunomodulatory oligonucleotides |
US5666153A (en) | 1995-10-03 | 1997-09-09 | Virtual Shopping, Inc. | Retractable teleconferencing apparatus |
DE19612967A1 (en) | 1996-04-01 | 1997-10-02 | Behringwerke Ag | Process for the propagation of influenza viruses in cell culture, and the influenza viruses obtainable by the process |
DE19612966B4 (en) | 1996-04-01 | 2009-12-10 | Novartis Vaccines And Diagnostics Gmbh & Co. Kg | MDCK cells and methods of propagating influenza viruses |
AU3399197A (en) | 1996-06-18 | 1998-01-07 | Alza Corporation | Device for enhancing transdermal agent delivery or sampling |
US5856462A (en) | 1996-09-10 | 1999-01-05 | Hybridon Incorporated | Oligonucleotides having modified CpG dinucleosides |
US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
JP4153999B2 (en) | 1996-12-20 | 2008-09-24 | アルザ・コーポレーション | Compositions and methods for enhancing transdermal agent flow |
AT405939B (en) | 1997-02-24 | 1999-12-27 | Immuno Ag | METHOD FOR INACTIVATING LIPID-ENVIRONED VIRUSES |
US5993412A (en) | 1997-05-19 | 1999-11-30 | Bioject, Inc. | Injection apparatus |
GB9711990D0 (en) | 1997-06-11 | 1997-08-06 | Smithkline Beecham Biolog | Vaccine |
CA2301000C (en) | 1997-08-28 | 2003-07-08 | Cheil Jedang Corporation | An attenuated japanese encephalitis virus adapted to vero cell and a japanese encephalitis vaccine |
GB9718901D0 (en) | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
CA2302554C (en) | 1997-09-05 | 2007-04-10 | Smithkline Beecham Biologicals S.A. | Oil in water emulsions containing saponins |
CA2305785A1 (en) | 1997-10-07 | 1999-04-15 | University Of Maryland Biotechnology Institute | Method for introducing and expressing rna in animal cells |
EP1035867A1 (en) | 1997-12-02 | 2000-09-20 | Powderject Vaccines, Inc. | Transdermal delivery of particulate vaccine compositions |
GB9727262D0 (en) | 1997-12-24 | 1998-02-25 | Smithkline Beecham Biolog | Vaccine |
HUP0101619A3 (en) | 1998-04-09 | 2003-11-28 | Smithkline Beecham Biolog | Adjuvant compositions |
PT1104306E (en) | 1998-08-10 | 2006-05-31 | Antigenics Inc | CPG COMPOSITIONS AND SAPONIN ADJUVANTS AND THEIR METHODS |
NZ511449A (en) | 1998-12-02 | 2004-05-28 | Univ Maryland | Plasmid maintenance system for antigen delivery |
US6492169B1 (en) | 1999-05-18 | 2002-12-10 | Crucell Holland, B.V. | Complementing cell lines |
EP1103610A1 (en) | 1999-11-26 | 2001-05-30 | Introgene B.V. | Production of vaccines from immortalised mammalian cell lines |
US7472098B2 (en) | 2000-02-14 | 2008-12-30 | Ubs Financial Services, Inc. | System and method for execution of trades made pursuant to stock option and purchase plans |
ES2349114T3 (en) | 2000-11-22 | 2010-12-28 | University Of Maryland, Baltimore | USE OF CLYA HEMOLISIN FOR THE EXCRETION OF FUSION PROTEINS. |
GB0326439D0 (en) | 2003-11-13 | 2003-12-17 | Imp College Innovations Ltd | Methods |
MX2007002372A (en) | 2004-08-27 | 2007-05-08 | Panacea Biotec Ltd | Inactivated poliomyelitis vaccine derived from sabin strain of polio virus. |
RS51665B (en) | 2004-09-09 | 2011-10-31 | Novartis Vaccines And Diagnostics Gmbh. | Decreasing potential iatrogenic risks associated with influenza vaccines |
EP1724338A1 (en) | 2005-05-19 | 2006-11-22 | Crucell Holland B.V. | Methods for the production of a whole-inactivated West Nile Virus vaccine |
CN101516395B (en) | 2006-09-01 | 2014-03-26 | 伯哈拉特生物技术国际有限公司 | A vaccine for chikungunya virus infection |
KR20170124619A (en) | 2009-03-27 | 2017-11-10 | 아카데미아 시니카 | Methods and compositions for immunization against virus |
US20100310656A1 (en) | 2009-04-27 | 2010-12-09 | Immunitor USA, Inc. | Immunotherapy and prevention of autoimmune hepatitis |
CN107050445A (en) | 2011-05-26 | 2017-08-18 | 葛兰素史密丝克莱恩生物有限公司 | Inactivated dengue virus vaccine |
SG10201607787RA (en) | 2011-06-17 | 2016-11-29 | Bharat Biotech Int Ltd | Vaccine Composition Comprising An Inactivated Chikungunya Virus Strain |
HUE037325T2 (en) | 2011-12-06 | 2018-08-28 | Valneva Austria Gmbh | Aluminium compounds for use in therapeutics and vaccines |
WO2013132040A2 (en) | 2012-03-08 | 2013-09-12 | Novartis Ag | In vitro potency assay for protein-based meningococcal vaccines |
WO2013132043A1 (en) | 2012-03-08 | 2013-09-12 | Novartis Ag | Combination vaccines with tlr4 agonists |
US9895437B2 (en) | 2012-04-18 | 2018-02-20 | Valneva Austria Gmbh | Aluminum compounds for use in therapeutics and vaccines |
WO2015059714A1 (en) | 2013-09-14 | 2015-04-30 | Bharat Biotech International Limited | Emergency mode in a hybrid vehicle |
EP3194595A4 (en) | 2014-09-17 | 2018-06-20 | University of Iowa Research Foundation | Viral rna segments as immunomodulatory agents and vaccine components |
PE20171132A1 (en) | 2014-10-07 | 2017-08-09 | Serum Inst Of India Private Ltd | IMPROVED METHODS FOR ENTEROVIRUS INACTIVATION AND ADSORPTION ON COADJUVANTS, AND REDUCED DOSE VACCINE COMPOSITIONS OBTAINED FROM THESE |
AR102547A1 (en) | 2014-11-07 | 2017-03-08 | Takeda Vaccines Inc | VACCINES AGAINST DISEASE OF HANDS, FEET AND MOUTH AND MANUFACTURING METHODS AND THEIR USE |
US10086061B2 (en) | 2015-03-11 | 2018-10-02 | The United States Of America, As Represented By The Secretary Of The Army, On Behalf Of The Walter Reed Army Institute Of Research | Combination purified inactivated vaccine for flaviviruses |
CN108472353A (en) | 2015-06-22 | 2018-08-31 | 哈佛大学校长及研究员协会 | Composition and method for adjusting virus infection |
AU2016291836A1 (en) * | 2015-07-16 | 2018-03-08 | Bharat Biotech International Limited | Vaccine compositions |
US11007260B2 (en) | 2015-07-21 | 2021-05-18 | Modernatx, Inc. | Infectious disease vaccines |
US11111481B2 (en) | 2015-09-30 | 2021-09-07 | Ramot At Tel-Aviv University Ltd. | Attenuated virus mutated at sites of evolutionarily conserved RNA structure |
WO2017070624A1 (en) | 2015-10-22 | 2017-04-27 | Modernatx, Inc. | Tropical disease vaccines |
EP3393507B1 (en) | 2015-12-23 | 2024-02-07 | Valneva Austria GmbH | Zika virus purification |
EP3184119A1 (en) | 2015-12-23 | 2017-06-28 | Themis Bioscience GmbH | Chromatography based purification strategies for measles scaffold based viruses |
US11434259B2 (en) | 2016-01-25 | 2022-09-06 | Iogenetics, Llc | Modified Zika virus NS1 protein with reduced cross-reactive immunogenicity |
SG10201913630YA (en) | 2016-02-17 | 2020-03-30 | Curevac Ag | Zika virus vaccine |
EP3419660A4 (en) | 2016-02-25 | 2019-11-06 | The Trustees Of The University Of Pennsylvania | Novel vaccines against zika virus |
WO2017161151A1 (en) | 2016-03-16 | 2017-09-21 | Novavax, Inc. | Vaccine compositions containing modified zika virus antigens |
CN105749268B (en) | 2016-04-11 | 2020-09-11 | 北京科兴中维生物技术有限公司 | Inactivated Zika virus vaccine |
WO2017181098A2 (en) | 2016-04-15 | 2017-10-19 | Visterra, Inc. | Antibody molecules to zika virus and uses thereof |
WO2017192856A1 (en) | 2016-05-04 | 2017-11-09 | University Of Miami | Zika virus vector for treating zika virus infection |
CA3022603A1 (en) | 2016-05-10 | 2017-11-16 | Najit Technologies, Inc. | Inactivating pathogens and producing highly immunogenic inactivated vaccines using a dual oxidation process |
US11033615B2 (en) | 2016-05-31 | 2021-06-15 | The Government of the United States, As Represented by the Secretary of the Army Fort Detrick, Maryland | Zika virus vaccine and methods of production |
WO2017208191A1 (en) | 2016-06-02 | 2017-12-07 | Glaxosmithkline Biologicals Sa | Zika viral antigen constructs |
EP3468593A4 (en) | 2016-06-09 | 2019-12-18 | Beth Israel Deaconess Medical Center, Inc. | Compositions and methods for preventing and treating zika virus infection |
GB201610162D0 (en) | 2016-06-10 | 2016-07-27 | Imp Innovations Ltd And Inst Pasteur | Methods |
BR112018075513A2 (en) | 2016-06-13 | 2019-10-01 | Us Health | nucleic acids encoding Zika virus-like particles and their use in vaccines and Zika virus diagnostic testing |
US10632185B2 (en) | 2016-07-08 | 2020-04-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric west nile/zika viruses and methods of use |
JP7046848B2 (en) | 2016-07-08 | 2022-04-04 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | Genome sequence encoding attenuated mutant Zika virus |
US11834494B2 (en) | 2016-07-26 | 2023-12-05 | Washington University | Antibodies to zika virus and methods of use thereof |
GB201613191D0 (en) | 2016-07-29 | 2016-09-14 | Univ Oxford Innovation Ltd | Zika virus vaccine |
BE1025121B1 (en) | 2016-11-17 | 2018-11-05 | Glaxosmithkline Biologicals Sa | ANTIGENIC CONSTRUCTS OF ZIKA VIRUS |
EP3558353A2 (en) | 2016-12-23 | 2019-10-30 | Expres2ion Biotechnologies ApS | New flavivirus vaccine |
CN108503696B (en) | 2017-02-27 | 2023-05-12 | 中国科学院上海巴斯德研究所 | Zika virus subunit vaccine expressed by yeast cells |
CN108503697B (en) | 2017-02-27 | 2023-03-31 | 中国科学院上海巴斯德研究所 | Zika virus subunit vaccine expressed by drosophila cells |
EP4205760A1 (en) | 2017-03-08 | 2023-07-05 | University of Georgia Research Foundation, Inc. | Methods and compositions related to increased viral production |
US11370830B2 (en) | 2017-04-07 | 2022-06-28 | The Rockefeller University | Neutralizing antibodies that bind to the zika virus domain III envelope region |
US11286502B2 (en) | 2017-06-20 | 2022-03-29 | Texas Tech University System | ZIKA virus like particle (VLP) based vaccine and microneutralization assay |
EP3417943B1 (en) | 2017-06-21 | 2020-02-12 | Eppendorf AG | Centrifuge rotor with seal |
CN107188935B (en) * | 2017-07-20 | 2018-10-02 | 北京健乃喜生物技术有限公司 | A kind of zika virus NS1 antigenic mutants and its application |
WO2019042555A1 (en) | 2017-08-31 | 2019-03-07 | Humabs Biomed Sa | Multispecific antibodies specifically binding to zika virus epitopes and uses thereof |
CN107537029B (en) | 2017-09-14 | 2021-03-19 | 北京科兴生物制品有限公司 | Zika virus and yellow fever virus combined inactivated vaccine |
GB201716254D0 (en) | 2017-10-05 | 2017-11-22 | Univ Leuven Kath | Live-attenuated flaviruses with heterologous antigens |
CN111615397A (en) * | 2017-11-03 | 2020-09-01 | 武田疫苗股份有限公司 | Zika vaccine and immunogenic compositions and methods of use thereof |
BR102017024030A2 (en) | 2017-11-08 | 2019-06-04 | Universidade Federal De São João Del Rei | IMMUNOGENIC RECOMBINANT PROTEIN WITH ZIKA ANTIGENS FOR VACCINE VIRUS AND ITS USES |
US20210054055A1 (en) | 2017-11-21 | 2021-02-25 | The University Of Vermont And State Agricultural College | Highly specific zika neutralizing human antibodies |
BR112020009960A2 (en) | 2017-11-30 | 2020-11-10 | Takeda Vaccines, Inc. | method for inactivating Zika virus and related methods |
CN108187036A (en) | 2017-12-08 | 2018-06-22 | 北京科兴中维生物技术有限公司 | A kind of zika virus combines inactivated vaccine with encephalitis B virus |
CN108210921A (en) | 2017-12-29 | 2018-06-29 | 广州恩宝生物医药科技有限公司 | A kind of zika virus vaccine and preparation method thereof |
WO2019162465A1 (en) | 2018-02-22 | 2019-08-29 | Nano4 Global, Lda | Method for detecting flaviviridae |
WO2019172982A1 (en) | 2018-03-08 | 2019-09-12 | Codagenix Inc. | Attenuated flaviviruses |
CN112292148A (en) | 2018-03-29 | 2021-01-29 | 埃默杰克斯疫苗控股有限公司 | Vaccine composition |
KR102075581B1 (en) | 2018-04-27 | 2020-02-10 | 가톨릭대학교 산학협력단 | Adjuvant comprising nucleic acid molecule inserted viral expression regulation sequence and phamraceutical composition having the adjuvant |
KR102253190B1 (en) | 2018-07-18 | 2021-05-18 | (주)진매트릭스 | A ZIKA virus Mutant and a vaccine composition comprising the same |
JP7320601B2 (en) | 2018-09-11 | 2023-08-03 | 上▲海▼市公共▲衛▼生▲臨▼床中心 | Broad-spectrum anti-influenza vaccine immunogen and its use |
EP3870208A4 (en) | 2018-10-26 | 2022-10-26 | New York Blood Center, Inc. | Zika virus immunogenic compositions |
JP7463366B2 (en) | 2018-11-20 | 2024-04-08 | タケダ ワクチン,インコーポレイテッド | Novel anti-Zika virus antibodies and uses thereof |
US20220211836A1 (en) | 2019-05-08 | 2022-07-07 | Takeda Vaccines, Inc. | Inactivated virus compositions and zika vaccine formulations |
WO2021262659A1 (en) | 2020-06-22 | 2021-12-30 | University Of Connecticut | Flavivirus signal peptides, vaccine constructs, and methods therefor |
-
2018
- 2018-11-05 CN CN201880071672.8A patent/CN111615397A/en active Pending
- 2018-11-05 BR BR112020008693-2A patent/BR112020008693A2/en unknown
- 2018-11-05 US US16/761,368 patent/US11648304B2/en active Active
- 2018-11-05 KR KR1020207015981A patent/KR20200117981A/en unknown
- 2018-11-05 KR KR1020207015983A patent/KR20200085302A/en active Search and Examination
- 2018-11-05 MX MX2020004367A patent/MX2020004367A/en unknown
- 2018-11-05 EP EP18807501.4A patent/EP3703739A2/en active Pending
- 2018-11-05 WO PCT/US2018/059219 patent/WO2019090228A2/en unknown
- 2018-11-05 SG SG11202003796XA patent/SG11202003796XA/en unknown
- 2018-11-05 CA CA3081586A patent/CA3081586A1/en active Pending
- 2018-11-05 MX MX2020004542A patent/MX2020004542A/en unknown
- 2018-11-05 MX MX2020004543A patent/MX2020004543A/en unknown
- 2018-11-05 CA CA3081581A patent/CA3081581A1/en active Pending
- 2018-11-05 WO PCT/US2018/059233 patent/WO2019090238A1/en unknown
- 2018-11-05 BR BR112020008652-5A patent/BR112020008652A2/en unknown
- 2018-11-05 EP EP18815389.4A patent/EP3703740A2/en active Pending
- 2018-11-05 CN CN201880071279.9A patent/CN111526885A/en active Pending
- 2018-11-05 CA CA3081578A patent/CA3081578A1/en active Pending
- 2018-11-05 AU AU2018359556A patent/AU2018359556B2/en active Active
- 2018-11-05 JP JP2020524599A patent/JP7443232B2/en active Active
- 2018-11-05 MY MYPI2020002167A patent/MY194449A/en unknown
- 2018-11-05 MY MYPI2020002164A patent/MY193736A/en unknown
- 2018-11-05 BR BR112020008665-7A patent/BR112020008665A2/en unknown
- 2018-11-05 JP JP2020524598A patent/JP2021502350A/en active Pending
- 2018-11-05 KR KR1020207015982A patent/KR20200083571A/en not_active Application Discontinuation
- 2018-11-05 US US16/761,329 patent/US11730802B2/en active Active
- 2018-11-05 CN CN201880070383.6A patent/CN111511395A/en active Pending
- 2018-11-05 AU AU2018359558A patent/AU2018359558C1/en active Active
- 2018-11-05 SG SG11202003800YA patent/SG11202003800YA/en unknown
- 2018-11-05 EP EP18815390.2A patent/EP3703741A1/en active Pending
- 2018-11-05 AU AU2018359660A patent/AU2018359660B2/en active Active
- 2018-11-05 WO PCT/US2018/059227 patent/WO2019090233A2/en unknown
- 2018-11-05 SG SG11202003949TA patent/SG11202003949TA/en unknown
- 2018-11-05 JP JP2020544571A patent/JP7295124B2/en active Active
- 2018-11-05 US US16/761,340 patent/US11478541B2/en active Active
-
2022
- 2022-02-18 AU AU2022201109A patent/AU2022201109B9/en active Active
- 2022-05-20 AU AU2022203422A patent/AU2022203422B2/en active Active
- 2022-07-26 AU AU2022209239A patent/AU2022209239B2/en active Active
-
2023
- 2023-06-16 US US18/336,439 patent/US20230414743A1/en active Pending
- 2023-09-08 JP JP2023146339A patent/JP2023175761A/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG11202003949TA (en) | Method for inactivating zika virus and for determining the completeness of inactivation | |
HK1249058A1 (en) | Compounds and methods for the enhanced degradation of targeted proteins | |
IL258533B (en) | Acoustic orthopedic tracking system and methods | |
IL247309A0 (en) | Compositions for the inactivation of virus replication and methods of making and using the same | |
IL247358B (en) | Device and method for continuous virus inactivation | |
HK1231402A1 (en) | Methods for the treatment of hepatitis b and hepatitis d virus infections b d | |
EP3206608A4 (en) | Systems and methods for intermedullary bone fixation | |
SG11202003975WA (en) | Method for inactivating zika virus and related methods | |
SG10201908584SA (en) | Fixed Dose Combinations And Formulations Comprising ETC1002 And One Or More Statins And Methods Of Treating Or Reducing The Risk Of Cardiovascular Disease | |
IL249400A0 (en) | Orthopedic splints and methods therefor | |
HK1253377A1 (en) | Programmable vaccine system for oncolytic viruses and application of the same | |
IL270989A (en) | Oncolytic virus and method | |
HK1252343A1 (en) | Compositions and methods for the treatment of viral infection | |
ZA201801164B (en) | Method and device for disinfecting inner surfaces of freezers and the like | |
EP3630175A4 (en) | Methods and devices for the treatment of food allergies | |
HK1253557A1 (en) | Methods of purification and/or viral inactivation | |
EP3731879A4 (en) | Plasma sterilization and drying system and methods | |
IL272779A (en) | Methods of inactivating viral contaminants | |
ZA202001060B (en) | Nodes and methods for handling paging | |
IL274161A (en) | Systems and methods for treating hyper-igm syndrome | |
EP3569687A4 (en) | Virus inactivation kit and virus inactivation device | |
ZA201705499B (en) | Method for cooking and sterilization | |
PL3284351T3 (en) | Method of pasteurizing and/or sterilising particulate material | |
GB201813832D0 (en) | Centrifugal fan and method for cleaning thereof | |
IL273229A (en) | Methods of inactivation of viruses using n-methylglucamide and its derivatives |