SG11202003910VA - ANTI-huTNFR1 THERAPY OF NONALCOHOLIC STEATOHEPATITIS - Google Patents

ANTI-huTNFR1 THERAPY OF NONALCOHOLIC STEATOHEPATITIS

Info

Publication number
SG11202003910VA
SG11202003910VA SG11202003910VA SG11202003910VA SG11202003910VA SG 11202003910V A SG11202003910V A SG 11202003910VA SG 11202003910V A SG11202003910V A SG 11202003910VA SG 11202003910V A SG11202003910V A SG 11202003910VA SG 11202003910V A SG11202003910V A SG 11202003910VA
Authority
SG
Singapore
Prior art keywords
hutnfr1
therapy
nonalcoholic steatohepatitis
nonalcoholic
steatohepatitis
Prior art date
Application number
SG11202003910VA
Inventor
Heike Bantel
Klaus Pfizenmaier
Andreas Herrmann
Original Assignee
Baliopharm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baliopharm Ag filed Critical Baliopharm Ag
Publication of SG11202003910VA publication Critical patent/SG11202003910VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
SG11202003910VA 2017-11-27 2018-11-27 ANTI-huTNFR1 THERAPY OF NONALCOHOLIC STEATOHEPATITIS SG11202003910VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17203853 2017-11-27
PCT/EP2018/082634 WO2019102023A1 (en) 2017-11-27 2018-11-27 ANTI-huTNFR1 THERAPY OF NONALCOHOLIC STEATOHEPATITIS

Publications (1)

Publication Number Publication Date
SG11202003910VA true SG11202003910VA (en) 2020-06-29

Family

ID=60473433

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202003910VA SG11202003910VA (en) 2017-11-27 2018-11-27 ANTI-huTNFR1 THERAPY OF NONALCOHOLIC STEATOHEPATITIS

Country Status (14)

Country Link
US (1) US11028178B2 (en)
EP (1) EP3717068A1 (en)
JP (1) JP7280259B2 (en)
KR (1) KR20200089699A (en)
CN (1) CN111787980A (en)
AU (1) AU2018371232A1 (en)
BR (1) BR112020010632A2 (en)
CA (1) CA3081493A1 (en)
EA (1) EA202091182A1 (en)
IL (1) IL274770A (en)
MX (1) MX2020005445A (en)
SG (1) SG11202003910VA (en)
TW (1) TW201925234A (en)
WO (1) WO2019102023A1 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4006269A1 (en) 1990-02-28 1991-08-29 Max Planck Gesellschaft Antibody which binds to tumour necrosis factor receptors
WO2007058894A2 (en) * 2005-11-10 2007-05-24 The University Of North Carolina At Chapel Hill Splice switching oligomers for tnf superfamily receptors and their use in treatment of disease
EP1972637B1 (en) 2007-03-19 2011-06-29 Universität Stuttgart huTNFR1 selective antagonists
PL2616489T3 (en) 2010-09-16 2017-07-31 Baliopharm Ag Anti-hutnfr1 antibody
CN105121460A (en) * 2013-03-06 2015-12-02 波塔力克斯有限公司 Use of plant cells expressing a TNFalpha polypeptide inhibitor in therapy
SG11201808680RA (en) 2016-04-05 2018-11-29 Univ Stuttgart MONOVALENT INHIBITOR OF huTNFR1 INTERACTION

Also Published As

Publication number Publication date
US20200299396A1 (en) 2020-09-24
IL274770A (en) 2020-07-30
JP7280259B2 (en) 2023-05-23
KR20200089699A (en) 2020-07-27
CN111787980A (en) 2020-10-16
AU2018371232A1 (en) 2020-05-21
TW201925234A (en) 2019-07-01
MX2020005445A (en) 2020-10-28
EP3717068A1 (en) 2020-10-07
BR112020010632A2 (en) 2020-11-10
EA202091182A1 (en) 2020-07-29
US11028178B2 (en) 2021-06-08
CA3081493A1 (en) 2019-05-31
JP2021504379A (en) 2021-02-15
WO2019102023A1 (en) 2019-05-31

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