SG11202003806WA - Novel compounds for use in treating depression and migraine - Google Patents

Novel compounds for use in treating depression and migraine

Info

Publication number
SG11202003806WA
SG11202003806WA SG11202003806WA SG11202003806WA SG11202003806WA SG 11202003806W A SG11202003806W A SG 11202003806WA SG 11202003806W A SG11202003806W A SG 11202003806WA SG 11202003806W A SG11202003806W A SG 11202003806WA SG 11202003806W A SG11202003806W A SG 11202003806WA
Authority
SG
Singapore
Prior art keywords
migraine
novel compounds
treating depression
depression
treating
Prior art date
Application number
SG11202003806WA
Inventor
Johannes Albertus Maria Smeitink
Julien David Beyrath
Original Assignee
Khondrion Ip B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Khondrion Ip B V filed Critical Khondrion Ip B V
Publication of SG11202003806WA publication Critical patent/SG11202003806WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/452Piperidinium derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202003806WA 2017-11-22 2018-11-22 Novel compounds for use in treating depression and migraine SG11202003806WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17203136 2017-11-22
PCT/EP2018/082143 WO2019101825A1 (en) 2017-11-22 2018-11-22 Novel compounds for use in treating depression and migraine

Publications (1)

Publication Number Publication Date
SG11202003806WA true SG11202003806WA (en) 2020-06-29

Family

ID=60569579

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202003806WA SG11202003806WA (en) 2017-11-22 2018-11-22 Novel compounds for use in treating depression and migraine

Country Status (12)

Country Link
US (2) US11357767B2 (en)
EP (1) EP3713563A1 (en)
JP (1) JP7405484B2 (en)
KR (1) KR20200090816A (en)
CN (1) CN111372582A (en)
AU (1) AU2018371152B2 (en)
BR (1) BR112020010207A2 (en)
CA (1) CA3079481A1 (en)
IL (1) IL274822B2 (en)
SG (1) SG11202003806WA (en)
WO (1) WO2019101825A1 (en)
ZA (1) ZA202002101B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2959243T3 (en) * 2017-04-05 2024-02-22 Khondrion Ip B V New treatment for mitochondrial diseases
US11672787B2 (en) * 2017-11-22 2023-06-13 Khondrion Ip B.V. Compounds as mPGES-1 inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001048784A (en) 1999-08-11 2001-02-20 Takeda Chem Ind Ltd Activator for mitochondrial function
JP5098051B2 (en) 2007-04-05 2012-12-12 Sbiファーマ株式会社 Mitochondrial disorder brain disease therapeutic agent and diagnostic agent
US20090281112A1 (en) * 2008-05-08 2009-11-12 Fabre-Kramer Pharmaceuticals, Inc. Adatanserin and metabolites thereof for treatment of attention deficit disorder, anxiety, depression, sexual dysfunction, and other disorders
US10058612B2 (en) 2011-04-26 2018-08-28 Retrotope, Inc. Impaired energy processing disorders and mitochondrial deficiency
LT2872497T (en) * 2012-07-12 2017-04-25 Khondrion Ip B.V. Chromanyl derivatives for treating mitochondrial disease
MX364547B (en) * 2012-07-12 2019-04-30 Khondrion Ip B V Chromanyl derivatives for treating mitochondrial disease.
US10815211B2 (en) * 2015-10-08 2020-10-27 Khondrion Ip B.V. Compounds for treating mitochondrial disease

Also Published As

Publication number Publication date
US20200289491A1 (en) 2020-09-17
CN111372582A (en) 2020-07-03
AU2018371152A1 (en) 2020-06-04
WO2019101825A1 (en) 2019-05-31
US11357767B2 (en) 2022-06-14
EP3713563A1 (en) 2020-09-30
US20220273636A1 (en) 2022-09-01
ZA202002101B (en) 2021-04-28
IL274822B2 (en) 2024-03-01
KR20200090816A (en) 2020-07-29
IL274822A (en) 2020-07-30
RU2020120239A (en) 2021-12-22
CA3079481A1 (en) 2019-05-31
AU2018371152B2 (en) 2024-02-08
JP2021504305A (en) 2021-02-15
IL274822B1 (en) 2023-11-01
BR112020010207A2 (en) 2020-10-13
JP7405484B2 (en) 2023-12-26

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