SG11202003391XA - Method for assessing the risk of cutaneous adverse drug reactions induced by anti-epileptic drug lamotrigine, detection reagent thereof and use thereof - Google Patents
Method for assessing the risk of cutaneous adverse drug reactions induced by anti-epileptic drug lamotrigine, detection reagent thereof and use thereofInfo
- Publication number
- SG11202003391XA SG11202003391XA SG11202003391XA SG11202003391XA SG11202003391XA SG 11202003391X A SG11202003391X A SG 11202003391XA SG 11202003391X A SG11202003391X A SG 11202003391XA SG 11202003391X A SG11202003391X A SG 11202003391XA SG 11202003391X A SG11202003391X A SG 11202003391XA
- Authority
- SG
- Singapore
- Prior art keywords
- assessing
- risk
- detection reagent
- lamotrigine
- reactions induced
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2017/107933 WO2019080077A1 (en) | 2017-10-27 | 2017-10-27 | Method for assessing the risk of cutaneous adverse drug reactions caused by anti-epileptic drug lamotrigine, detection reagent thereof and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202003391XA true SG11202003391XA (en) | 2020-05-28 |
Family
ID=66247078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202003391XA SG11202003391XA (en) | 2017-10-27 | 2017-10-27 | Method for assessing the risk of cutaneous adverse drug reactions induced by anti-epileptic drug lamotrigine, detection reagent thereof and use thereof |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20200318189A1 (en) |
| JP (2) | JP2021500083A (en) |
| KR (1) | KR20200077555A (en) |
| CN (1) | CN111278990A (en) |
| SG (1) | SG11202003391XA (en) |
| WO (1) | WO2019080077A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114588162B (en) * | 2022-03-30 | 2023-10-27 | 中国人民解放军空军军医大学 | Use of lamotrigine for the treatment of autism haptic abnormalities |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004012741A1 (en) * | 2002-07-29 | 2004-02-12 | Glaxo Group Limited | Sustained release formulations comprising lamotrigine |
| US7470513B2 (en) * | 2003-11-10 | 2008-12-30 | Academia Sinica | Risk assessment for adverse drug reactions |
| CN103827312B (en) * | 2011-06-23 | 2016-06-15 | 长庚医疗财团法人基隆长庚纪念医院 | Assessment antiepileptic drug Phenytoin Sodium Salt causes the method for adverse drug reaction risk |
| CN105963311A (en) * | 2016-07-13 | 2016-09-28 | 欧阳冬生 | Application of composition of ginsenoside C-K and lamotrigine in preparation of anti-epilepsy medicines |
| CN106191300A (en) * | 2016-09-22 | 2016-12-07 | 中南大学湘雅三医院 | The biomarker of prediction child patient severe drug skin adverse reaction and application |
-
2017
- 2017-10-27 CN CN201780096270.9A patent/CN111278990A/en active Pending
- 2017-10-27 SG SG11202003391XA patent/SG11202003391XA/en unknown
- 2017-10-27 JP JP2020543661A patent/JP2021500083A/en active Pending
- 2017-10-27 US US16/759,151 patent/US20200318189A1/en not_active Abandoned
- 2017-10-27 WO PCT/CN2017/107933 patent/WO2019080077A1/en active Application Filing
- 2017-10-27 KR KR1020207014822A patent/KR20200077555A/en not_active Application Discontinuation
-
2022
- 2022-03-24 JP JP2022048589A patent/JP2022084843A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN111278990A (en) | 2020-06-12 |
| JP2021500083A (en) | 2021-01-07 |
| US20200318189A1 (en) | 2020-10-08 |
| JP2022084843A (en) | 2022-06-07 |
| KR20200077555A (en) | 2020-06-30 |
| WO2019080077A1 (en) | 2019-05-02 |
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| SG11202003391XA (en) | Method for assessing the risk of cutaneous adverse drug reactions induced by anti-epileptic drug lamotrigine, detection reagent thereof and use thereof |