SG11202002475TA - Use of fused heteroaromatic pyrrolidones for treatment and prevention of diseases in animals - Google Patents

Use of fused heteroaromatic pyrrolidones for treatment and prevention of diseases in animals

Info

Publication number
SG11202002475TA
SG11202002475TA SG11202002475TA SG11202002475TA SG11202002475TA SG 11202002475T A SG11202002475T A SG 11202002475TA SG 11202002475T A SG11202002475T A SG 11202002475TA SG 11202002475T A SG11202002475T A SG 11202002475TA SG 11202002475T A SG11202002475T A SG 11202002475TA
Authority
SG
Singapore
Prior art keywords
animals
diseases
prevention
treatment
fused heteroaromatic
Prior art date
Application number
SG11202002475TA
Inventor
Nils Griebenow
Maria Mottier
Gerald Beddies
Jörg Cramer
Ulf Bömer
Iring Heisler
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of SG11202002475TA publication Critical patent/SG11202002475TA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
SG11202002475TA 2017-10-19 2018-10-15 Use of fused heteroaromatic pyrrolidones for treatment and prevention of diseases in animals SG11202002475TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17197344 2017-10-19
PCT/EP2018/078086 WO2019076817A1 (en) 2017-10-19 2018-10-15 Use of fused heteroaromatic pyrrolidones for treatment and prevention of diseases in animals

Publications (1)

Publication Number Publication Date
SG11202002475TA true SG11202002475TA (en) 2020-04-29

Family

ID=60143623

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202002475TA SG11202002475TA (en) 2017-10-19 2018-10-15 Use of fused heteroaromatic pyrrolidones for treatment and prevention of diseases in animals

Country Status (18)

Country Link
US (1) US11077111B2 (en)
EP (1) EP3665171A1 (en)
JP (1) JP2020537678A (en)
KR (1) KR20200073216A (en)
CN (1) CN111194319A (en)
AU (1) AU2018350683A1 (en)
BR (1) BR112020007679A2 (en)
CA (1) CA3079292A1 (en)
CL (1) CL2020001036A1 (en)
DO (1) DOP2020000093A (en)
IL (1) IL273834A (en)
MX (1) MX2020004155A (en)
PH (1) PH12020550444A1 (en)
RU (1) RU2020116178A (en)
SG (1) SG11202002475TA (en)
TW (1) TW201922744A (en)
UY (1) UY37945A (en)
WO (1) WO2019076817A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20180094A1 (en) 2017-10-18 2019-04-18 Hk Inno N Corp Heterocyclic compound as a protein kinase inhibito

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60017898T2 (en) 1999-06-09 2006-01-12 Yamanouchi Pharmaceutical Co., Ltd. NOVEL HETEROCYCLIC CARBOXAMIDE DERIVATIVES
GB9918035D0 (en) 1999-07-30 1999-09-29 Novartis Ag Organic compounds
JP2001302667A (en) 2000-04-28 2001-10-31 Bayer Ag Imidazopyrimidine derivative and triazolopyrimidine derivative
US20030158195A1 (en) 2001-12-21 2003-08-21 Cywin Charles L. 1,6 naphthyridines useful as inhibitors of SYK kinase
TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
EP1605946B1 (en) 2003-03-25 2008-05-28 Vertex Pharmaceuticals Incorporated Thiazoles useful as inhibitors of protein kinases
CN1849318B (en) 2003-07-30 2011-10-12 里格尔药品股份有限公司 Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds
WO2006129100A1 (en) 2005-06-03 2006-12-07 Glaxo Group Limited Novel compounds
US20070203161A1 (en) 2006-02-24 2007-08-30 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the jak pathway
RU2459821C2 (en) 2006-09-07 2012-08-27 Байоджен Айдек Ма Инк. Modulators of interleukin-1 receptor-associated kinase
BR122020010759B1 (en) 2007-03-12 2021-06-29 Ym Biosciences Australia Pty Ltd PHENYL AMINO PYRIMIDINE COMPOUNDS PROTEIN KINASES INHIBITORS, PROCESS FOR THE PREPARATION OF THE COMPOUND, PHARMACEUTICAL COMPOSITION, AND, IMPLANTATION
US7705004B2 (en) 2007-08-17 2010-04-27 Portola Pharmaceuticals, Inc. Protein kinase inhibitors
SG165655A1 (en) 2008-04-16 2010-11-29 Portola Pharm Inc 2, 6-diamino- pyrimidin- 5-yl-carboxamides as syk or JAK kinases inhibitors
JP5705720B2 (en) 2008-04-16 2015-04-22 ポートラ ファーマシューティカルズ, インコーポレイテッド 2,6-Diamino-pyrimidin-5-yl-carboxamide as SYK or JAK kinase inhibitor
SI2716157T1 (en) 2008-12-08 2016-10-28 Gilead Connecticut, Inc., c/o Gilead Sciences, Inc. Imidazopyrazine Syk inhibitors
CN102858767B (en) 2009-12-17 2015-08-19 默沙东公司 As the aminopyrimidine of SYK inhibitor
PT2516434E (en) * 2009-12-23 2015-10-05 Takeda Pharmaceutical Fused heteroaromatic pyrrolidinones as syk inhibitors
US9073892B2 (en) 2010-12-20 2015-07-07 Merck Serono S.A. Indazolyl triazol derivatives
GB201104153D0 (en) 2011-03-11 2011-04-27 Glaxo Group Ltd Novel compounds
WO2012177714A1 (en) * 2011-06-22 2012-12-27 Takeda Pharmaceutical Company Limited Substituted 6-aza-isoindolin-1-one derivatives
TWI735853B (en) 2013-12-23 2021-08-11 美商克洛諾斯生技有限公司 Syk inhibitors
JP6526065B2 (en) * 2014-02-28 2019-06-05 ニンバス ラクシュミ, インコーポレイテッド TYK2 inhibitors and uses thereof
AU2015365580B2 (en) 2014-12-18 2020-04-02 Takeda Pharmaceutical Company Limited Solid state forms of fused heteroaromatic pyrrolidinones
EP3262049B1 (en) * 2015-02-27 2022-07-20 Nimbus Lakshmi, Inc. Tyk2 inhibitors and uses thereof
PT3464266T (en) 2016-06-01 2021-11-23 Bayer Pharma AG Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseases in animals

Also Published As

Publication number Publication date
US20200261461A1 (en) 2020-08-20
WO2019076817A1 (en) 2019-04-25
MX2020004155A (en) 2020-08-03
CA3079292A1 (en) 2019-04-25
JP2020537678A (en) 2020-12-24
CN111194319A (en) 2020-05-22
AU2018350683A1 (en) 2020-04-02
EP3665171A1 (en) 2020-06-17
KR20200073216A (en) 2020-06-23
RU2020116178A (en) 2021-11-19
BR112020007679A2 (en) 2020-10-20
TW201922744A (en) 2019-06-16
US11077111B2 (en) 2021-08-03
UY37945A (en) 2019-05-31
CL2020001036A1 (en) 2020-10-23
PH12020550444A1 (en) 2021-04-26
IL273834A (en) 2020-05-31
DOP2020000093A (en) 2020-09-30

Similar Documents

Publication Publication Date Title
HK1258588A1 (en) Compounds and formulations for treating ophthalmic diseases
IL246564A (en) 3-aryl-1-heterocyclyl-pyrazolo[3,4-d]pyrimidine derivatives and use thereof in the treatment of diseases
ZA201908165B (en) Compounds for the prevention and treatment of diseases and the use thereof
IL263132B (en) Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseases in animals
IL265955A (en) Therapeutic compounds and methods of use thereof
IL274578A (en) Compounds and pharmaceutical compositions thereof for use in the treatment of fibrotic diseases
SG10201402819WA (en) Composition for prevention and treatment of joint pain and the method of preparation thereof
ZA201804950B (en) Indolinones compounds and their use in the treatment of fibrotic diseases
IL264069A (en) Trpa1 antagonists for treatment of dry eye, ocular pain and inflammation
IL264407A (en) Novel application of gzd824 and pharmaceutically acceptable salts thereof in treating diseases
GB201617064D0 (en) Compounds and their therapeutic use
HK1257236A1 (en) Medicine for preventing and treating hyperlipemia diseases and use of the medicine
GB201715194D0 (en) Compounds and their therapeutic use
HK1257585A1 (en) Medicine for preventing and treating skin fibrosis and use of the medicine
GB201519557D0 (en) Compounds for use in the treatment of telomere related diseases and/or telomere related medical conditions
IL272495A (en) Compounds and pharmaceutical compositions thereof for use in the treatment of fibrotic diseases
IL273834A (en) Use of fused heteroaromatic pyrrolidones for treatment and prevention of diseases in animals
HUE045532T2 (en) Preventive and/or therapeutic agent for immune diseases
HUE056301T2 (en) Salt of substituted urea derivative and use thereof in medicine
PL3515409T3 (en) Complex and compositions for the treatment of ophthalmic and dermatological diseases
EP3377062C0 (en) Aminonaphthoquinone compounds for treatment and/or prevention of fibrosis diseases
IL259383A (en) Compound for use in the prevention and treatment of neurodegenerative diseases
RS65201B1 (en) Indoline derivatives for treatment and/or prevention of fibrosis diseases
EP3272349A4 (en) Therapeutic and/or prophylactic agent for lewy body diseases
GB201410869D0 (en) Novel pharmaceutical formulations and their use in the treatment of periodontal disease