SG11202002118XA - Method for developing organ that lacks specific functional cell - Google Patents

Method for developing organ that lacks specific functional cell

Info

Publication number
SG11202002118XA
SG11202002118XA SG11202002118XA SG11202002118XA SG11202002118XA SG 11202002118X A SG11202002118X A SG 11202002118XA SG 11202002118X A SG11202002118X A SG 11202002118XA SG 11202002118X A SG11202002118X A SG 11202002118XA SG 11202002118X A SG11202002118X A SG 11202002118XA
Authority
SG
Singapore
Prior art keywords
specific functional
functional cell
lacks specific
developing organ
organ
Prior art date
Application number
SG11202002118XA
Inventor
Hiroshi Nagashima
Hitomi Matsunari
Kazuaki Nakano
Koki Hasegawa
Original Assignee
Univ Meiji
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Meiji filed Critical Univ Meiji
Publication of SG11202002118XA publication Critical patent/SG11202002118XA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8778—Swine embryos
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/10—Animals modified by protein administration, for non-therapeutic purpose
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/12—Animals modified by administration of exogenous cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A01K2217/054—Animals comprising random inserted nucleic acids (transgenic) inducing loss of function
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/108—Swine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/02—Animal zootechnically ameliorated
    • A01K2267/025—Animal producing cells or organs for transplantation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11202002118XA 2017-09-19 2018-09-18 Method for developing organ that lacks specific functional cell SG11202002118XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017178552 2017-09-19
PCT/JP2018/034390 WO2019059158A1 (en) 2017-09-19 2018-09-18 Method for developing organ lacking specific functional cell

Publications (1)

Publication Number Publication Date
SG11202002118XA true SG11202002118XA (en) 2020-04-29

Family

ID=65655803

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202002118XA SG11202002118XA (en) 2017-09-19 2018-09-18 Method for developing organ that lacks specific functional cell

Country Status (6)

Country Link
US (2) US11172657B2 (en)
EP (1) EP3685661A4 (en)
JP (2) JP6479246B1 (en)
SG (1) SG11202002118XA (en)
TW (1) TW201920655A (en)
WO (1) WO2019059158A1 (en)

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL106368A0 (en) 1992-07-24 1993-11-15 Univ Pennsylvania Non-native liver generation in an animal with impaired native liver function,by cell implantation
US6071697A (en) 1992-08-03 2000-06-06 Max-Planck Gesellschaft Zur Forderung Der Wissenschaften E.V. Method for testing the differentiation status in pancreatic cells of a mammal
EP0700297B1 (en) 1993-05-24 2002-07-31 Ximerex, Inc. Surrogate tolerogenesis for the development of tolerance to xenografts
JP3631765B2 (en) 1996-12-31 2005-03-23 マックス プランク ゲゼルシャフト ツール フェルデルング デル ヴィーセンシャフテン エーファウ A novel method for testing the differentiation status of mammalian pancreatic cells
CA2325721A1 (en) 1998-03-30 1999-10-07 Research Development Foundation Corticotropin releasing factor receptor 1-deficient mice
DK1162995T3 (en) * 1999-03-17 2003-06-23 Solvay Pharm Gmbh Enzymes for the treatment of type I diabetes mellitus
US6525242B1 (en) 1999-11-02 2003-02-25 The University Of Connecticut Propagation of human hepatocytes in non-human mammals
US7628988B2 (en) 2002-06-27 2009-12-08 The General Hospital Corporation Methods and compositions for treating type 1 diabetes
PL1928519T3 (en) * 2005-08-26 2012-08-31 Univ Minnesota Decellularization and recellularization of organs and tissues
EP1878342A1 (en) * 2006-07-13 2008-01-16 Institut Pasteur Immunodeficient mice transgenic for HLA class I and HLA class II molecules and their uses
CN101679950A (en) * 2007-02-22 2010-03-24 国立大学法人东京大学 Organ regeneration method utilizing blastocyst complementation
WO2009104794A1 (en) 2008-02-22 2009-08-27 国立大学法人 東京大学 Method for producing founder animal for reproducing animals having lethal phenotype caused by gene modification
US20110258715A1 (en) * 2008-08-22 2011-10-20 The University Of Tokyo ORGAN REGENERATION METHOD UTILIZING iPS CELL AND BLASTOCYST COMPLEMENTATION
KR20180036810A (en) 2009-08-14 2018-04-09 레비비코르 인코포레이션 Multi-transgenic pigs for diabetes treatment
US20110218191A1 (en) * 2010-03-03 2011-09-08 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the long term-treatment of kidney disorders in cats
JP5841322B2 (en) * 2010-04-22 2016-01-13 オレゴン ヘルス アンド サイエンス ユニバーシティ Fumaryl acetoacetate hydrolase (FAH) deficient pig and use thereof
JP6530342B2 (en) 2016-03-30 2019-06-12 株式会社日立製作所 Elevator equipment
WO2018139502A1 (en) * 2017-01-25 2018-08-02 国立大学法人 東京大学 Finding and treatment of inflammation after birth in chimeric animal

Also Published As

Publication number Publication date
US20200165633A1 (en) 2020-05-28
WO2019059158A1 (en) 2019-03-28
EP3685661A1 (en) 2020-07-29
TW201920655A (en) 2019-06-01
JP2019062929A (en) 2019-04-25
JP6479246B1 (en) 2019-03-06
EP3685661A4 (en) 2021-05-19
US11172657B2 (en) 2021-11-16
JP2019054790A (en) 2019-04-11
US20220022433A1 (en) 2022-01-27

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