SG11202001401TA - Separation of triple-light chain antibodies using cation exchange chromatography - Google Patents
Separation of triple-light chain antibodies using cation exchange chromatographyInfo
- Publication number
- SG11202001401TA SG11202001401TA SG11202001401TA SG11202001401TA SG11202001401TA SG 11202001401T A SG11202001401T A SG 11202001401TA SG 11202001401T A SG11202001401T A SG 11202001401TA SG 11202001401T A SG11202001401T A SG 11202001401TA SG 11202001401T A SG11202001401T A SG 11202001401TA
- Authority
- SG
- Singapore
- Prior art keywords
- triple
- separation
- light chain
- cation exchange
- exchange chromatography
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762562188P | 2017-09-22 | 2017-09-22 | |
| PCT/US2018/052212 WO2019060718A1 (en) | 2017-09-22 | 2018-09-21 | Separation of triple-light chain antibodies using cation exchange chromatography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202001401TA true SG11202001401TA (en) | 2020-04-29 |
Family
ID=65810610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202001401TA SG11202001401TA (en) | 2017-09-22 | 2018-09-21 | Separation of triple-light chain antibodies using cation exchange chromatography |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20190112359A1 (en) |
| EP (1) | EP3684409A4 (en) |
| JP (2) | JP2020534332A (en) |
| KR (1) | KR20200056396A (en) |
| CN (1) | CN111163804A (en) |
| AU (1) | AU2018338205A1 (en) |
| CA (1) | CA3073414A1 (en) |
| IL (1) | IL272849A (en) |
| MA (1) | MA50195A (en) |
| SG (1) | SG11202001401TA (en) |
| TW (1) | TWI826393B (en) |
| WO (1) | WO2019060718A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014312086B2 (en) | 2013-08-30 | 2020-03-12 | Immunogen, Inc. | Antibodies and assays for detection of folate receptor 1 |
| JP7203497B2 (en) | 2015-06-29 | 2023-01-13 | イミュノジェン・インコーポレーテッド | Anti-CD123 Antibodies, and Conjugates and Derivatives Thereof |
| TW202100557A (en) | 2019-04-29 | 2021-01-01 | 美商免疫遺傳股份有限公司 | Biparatopic fr-alpha antibodies and immunoconjugates |
| KR20220004669A (en) | 2019-04-29 | 2022-01-11 | 이뮤노젠 아이엔씨 | Therapeutic Combinations Comprising Anti-CD123 Immunoconjugates |
| EP4028420A1 (en) | 2019-09-13 | 2022-07-20 | Mythic Therapeutics, Inc. | Antigen-binding protein constructs and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| TWI318983B (en) * | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
| RU2412947C2 (en) | 2004-09-23 | 2011-02-27 | Дженентек, Инк. | Antibodies, constructed on cysteine basis and their conjugates |
| RU2498991C2 (en) * | 2007-10-30 | 2013-11-20 | Дженентек, Инк. | Purification of antibodies with cation-exchange chromatography |
| JP2011509675A (en) | 2008-01-18 | 2011-03-31 | メディミューン，エルエルシー | Cysteine engineered antibodies for site-specific conjugation |
| JP5918129B2 (en) | 2009-06-22 | 2016-05-18 | メディミューン，エルエルシー | Engineered Fc region for site-specific conjugation |
| US9650411B2 (en) * | 2012-08-07 | 2017-05-16 | Kyowa Hakko Kirin Co., Ltd. | Method of purifying protein |
| ES2843546T3 (en) * | 2014-04-18 | 2021-07-19 | The Research Foundation Of The State Univ Of New York | Humanized anti-TF-antigen antibodies |
| JP7203497B2 (en) * | 2015-06-29 | 2023-01-13 | イミュノジェン・インコーポレーテッド | Anti-CD123 Antibodies, and Conjugates and Derivatives Thereof |
| SI3313845T1 (en) | 2015-06-29 | 2021-01-29 | Immunogen, Inc. | Conjugates of cysteine engineered antibodies |
-
2018
- 2018-09-21 CA CA3073414A patent/CA3073414A1/en active Pending
- 2018-09-21 TW TW107133357A patent/TWI826393B/en active
- 2018-09-21 EP EP18859626.6A patent/EP3684409A4/en active Pending
- 2018-09-21 CN CN201880064102.6A patent/CN111163804A/en active Pending
- 2018-09-21 US US16/138,177 patent/US20190112359A1/en active Pending
- 2018-09-21 MA MA050195A patent/MA50195A/en unknown
- 2018-09-21 AU AU2018338205A patent/AU2018338205A1/en active Pending
- 2018-09-21 KR KR1020207009516A patent/KR20200056396A/en not_active Application Discontinuation
- 2018-09-21 WO PCT/US2018/052212 patent/WO2019060718A1/en unknown
- 2018-09-21 SG SG11202001401TA patent/SG11202001401TA/en unknown
- 2018-09-21 JP JP2020516736A patent/JP2020534332A/en active Pending
-
2020
- 2020-02-23 IL IL272849A patent/IL272849A/en unknown
-
2023
- 2023-06-20 JP JP2023100669A patent/JP2023112042A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| TWI826393B (en) | 2023-12-21 |
| MA50195A (en) | 2020-07-29 |
| AU2018338205A1 (en) | 2020-05-07 |
| JP2020534332A (en) | 2020-11-26 |
| US20190112359A1 (en) | 2019-04-18 |
| KR20200056396A (en) | 2020-05-22 |
| IL272849A (en) | 2020-04-30 |
| JP2023112042A (en) | 2023-08-10 |
| RU2020107752A (en) | 2021-10-22 |
| CN111163804A (en) | 2020-05-15 |
| EP3684409A4 (en) | 2021-06-23 |
| WO2019060718A1 (en) | 2019-03-28 |
| RU2020107752A3 (en) | 2022-04-27 |
| CA3073414A1 (en) | 2019-03-28 |
| EP3684409A1 (en) | 2020-07-29 |
| TW201915011A (en) | 2019-04-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1257164A1 (en) | Novel anti-pd-l1 antibodies | |
| IL255727A (en) | Novel anti-pd-l1 antibodies | |
| ZA201900353B (en) | Anti-pd-l1 antibodies | |
| IL262295B1 (en) | Anti-pd-l1 antibodies | |
| HK1246324A1 (en) | Anti-pd-l1 antibodies | |
| IL261188A (en) | Antibodies to tigit | |
| IL257062A (en) | Novel anti-pd-1 antibodies | |
| ZA201803874B (en) | Humanized anti-cd73 antibodies | |
| HK1249114A1 (en) | Monoclonal antibodies against bcma | |
| RS61204B1 (en) | Anti-pd-1 antibodies | |
| EP3433277A4 (en) | Novel anti-pd-l1 antibodies | |
| IL272849A (en) | Separation of triple-light chain antibodies using cation exchange chromatography | |
| HK1258375A1 (en) | Humanized anti-cll-1 antibodies | |
| IL273393A (en) | Novel anti-cd3epsilon antibodies | |
| IL256579A (en) | Humanized antibodies | |
| ZA201901865B (en) | Anti-pd-1 antibodies | |
| IL262776A (en) | Humanized anti-il-1r3 antibodies | |
| HK1250046A1 (en) | Anti-dkk-1-anti-rankl bispecific antibody compounds | |
| PL3371216T3 (en) | Humanized anti-bag3 antibodies | |
| GB201609742D0 (en) | Improvements relating to antibodies | |
| IL253518A0 (en) | Assays for highlypositively charged protein | |
| GB201511196D0 (en) | Monoclonal antibodies | |
| IL272015A (en) | Antibodies to MADCAM |